Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jose L Ortega Roldan"'
Autor:
Jose L Ortega Roldan, Salvador Casares, Malene Ringkjøbing Jensen, Nayra Cárdenes, Jerónimo Bravo, Martin Blackledge, Ana I Azuaga, Nico A J van Nuland
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73018 (2013)
SH3 domains constitute a new type of ubiquitin-binding domains. We previously showed that the third SH3 domain (SH3-C) of CD2AP binds ubiquitin in an alternative orientation. We have determined the structure of the complex between first CD2AP SH3 dom
Externí odkaz:
https://doaj.org/article/f0dfce6381094a71b4f4d8cd64cd8eef
Autor:
Fisayo Olotu, Encarnacion Medina-Carmona, Angela Serrano-Sanchez, Felipe Ossa, Abdelaziz El-Hamdaoui, Özlem Tastan Bishop, Jose L. Ortega-Roldan, Vahitha B. Abdul-Salam
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 688-701 (2023)
The use of computer-aided methods have continued to propel accelerated drug discovery across various disease models, interestingly allowing the specific inhibition of pathogenic targets. Chloride Intracellular Channel Protein 4 (CLIC4) is a novel cla
Externí odkaz:
https://doaj.org/article/6eee98be897b4998ba4e965cd2a5c06a
Autor:
Silvia Anselmi, Alexandra T. P. Carvalho, Angela Serrano-Sanchez, Jose L. Ortega-Roldan, Jill Caswell, Iman Omar, Gustavo Perez-Ortiz, Sarah M. Barry, Thomas S. Moody, Daniele Castagnolo
Publikováno v:
ACS Catalysis. 13:4742-4751
Autor:
Fisayo Olotu, Encarnacion Medina-Carmona, Angela Serrano-Sanchez, Felipe Ossa, Abdelaziz El-Hamdaoui, Özlem Tastan Bishop, Jose L. Ortega-Roldan, Vahitha B. Abdul-Salam
Supplementary data associated with this article can be found in the online version at doi:10.1016/j.csbj.2022.12.040.
Acknowledgment We would like to thank the Center for High-Performance Computing, Cape Town, South Africa for providing computat
Acknowledgment We would like to thank the Center for High-Performance Computing, Cape Town, South Africa for providing computat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7854f354b368eb2db4da2344c0230c96
https://hdl.handle.net/10481/80036
https://hdl.handle.net/10481/80036
Autor:
Angela Serrano-Sanchez, Joseph Cassar, Lisa J. White, Precious I. A. Popoola, Jennifer R. Hiscock, Jose L. Ortega-Roldan
Quantifying small molecule uptake across a biological membrane in any cell system is crucial for the development of efficacious and selective drugs. However, obtaining such data is not trivial, especially in bacterial systems. Herein, we present an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cca827e8f9eab73deb41ef280db4c852
https://doi.org/10.1101/2022.10.01.510446
https://doi.org/10.1101/2022.10.01.510446
Autor:
Jessica E. Boles, Charlotte Bennett, Jennifer Baker, Kira L. F. Hilton, Hiral A. Kotak, Ewan R. Clark, Yifan Long, Lisa J. White, Hin Yuk Lai, Charlotte K. Hind, J. Mark Sutton, Michelle D. Garrett, Anne Cheasty, Jose L. Ortega-Roldan, Mark Charles, Cally J. E. Haynes, Jennifer R. Hiscock
The rise of antimicrobial resistance remains one of the greatest global health threats facing humanity. Furthermore, the development of novel antibiotics has all but ground to a halt due to a collision of intersectional pressures. Herein we determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21e6bf211f33a882a85a150f6c66f7d
Autor:
Lorena Varela, Alex C. Hendry, Joseph Cassar, Ruben Martin-Escolano, Diego Cantoni, Felipe Ossa, John C. Edwards, Vahitha Abdul-Salam, Jose L. Ortega-Roldan
Publikováno v:
Journal of Cell Science. 135
The chloride intracellular channel (CLIC) protein family displays the unique feature of altering its structure from a soluble form to a membrane-bound chloride channel. CLIC1, a member of this family, is found in the cytoplasm or in internal and plas
Autor:
Fisayo Olotu, Encarnacion Medina-Carmona, Abdelaziz El-Hamdaoui, Özlem Tastan Bishop, Jose L. Ortega-Roldan, Vahitha B. Abdul-Salam
Chloride Intracellular Channel Protein 4 (CLIC4) is a novel class of intracellular ion channel highly implicated in tumour and vascular biology. It regulates cell proliferation, apoptosis and angiogenesis; and is involved in multiple pathologic signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bde7ccf0c661dce55712da9d98ff1827
https://doi.org/10.1101/2022.04.21.489122
https://doi.org/10.1101/2022.04.21.489122
Autor:
Lorena Varela, Alex C. Hendry, Joseph Cassar, Ruben Martin-Escolano, Diego Cantoni, John C Edwards, Vahitha Abdul-Salam, Jose L. Ortega-Roldan
The CLIC protein family displays the unique feature of altering its structure from a soluble form to a membrane-bound chloride channel. CLIC1, a member of this family, is found in the cytoplasm or in internal and the plasma membranes, with membrane r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdea6cfe28ef8879a65e50635635bc21
https://doi.org/10.1101/2021.10.25.465729
https://doi.org/10.1101/2021.10.25.465729
Autor:
Jerónimo Bravo, Martin Blackledge, Ana I. Azuaga, Salvador Casares, Jose L. Ortega Roldan, Nico A. J. van Nuland, Malene Ringkjøbing Jensen, Nayra Cardenes
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (9), pp.e73018. ⟨10.1371/journal.pone.0073018⟩
PLoS ONE, Vol 8, Iss 9, p e73018 (2013)
Digibug. Repositorio Institucional de la Universidad de Granada
PLoS ONE, 2013, 8 (9), pp.e73018. ⟨10.1371/journal.pone.0073018⟩
instname
PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (9), pp.e73018. ⟨10.1371/journal.pone.0073018⟩
PLoS ONE, Vol 8, Iss 9, p e73018 (2013)
Digibug. Repositorio Institucional de la Universidad de Granada
PLoS ONE, 2013, 8 (9), pp.e73018. ⟨10.1371/journal.pone.0073018⟩
14 páginas, 6 figuras. En material suplementario: 3 figuras, 2 tablas
SH3 domains constitute a new type of ubiquitin-binding domains. We previously showed that the third SH3 domain (SH3-C) of CD2AP binds ubiquitin in an alternative orientation.
SH3 domains constitute a new type of ubiquitin-binding domains. We previously showed that the third SH3 domain (SH3-C) of CD2AP binds ubiquitin in an alternative orientation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae08e2075a94efa9026ee2a370fc57a2
http://hdl.handle.net/10261/82349
http://hdl.handle.net/10261/82349