Výsledky vyhledávání - "Jose L Fernandez-Luna"

Akademický článek

Plasmonic Biosensing for Label-Free Detection of Two Hallmarks of Cancer Cells: Cell-Matrix Interaction and Cell Division

Autor: Maria Carcelen, Veronica Vidal, Alfredo Franco, Marcos Gomez, Fernando Moreno, Jose L Fernandez-Luna

Publikováno v: Biosensors, Vol 12, Iss 9, p 674 (2022)

Two key features of cancer cells are sustained proliferation and invasion, which is preceded by a modification of the adhesion properties to the extracellular matrix. Currently, fluorescence-based techniques are mainly used to detect these processes,

Externí odkaz: https://doaj.org/article/7ea212092c584de79ad9fc38e2a2ab6d

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Akademický článek

Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells.

Autor: Beatriz Aldaz, Ainara Sagardoy, Lorena Nogueira, Elizabeth Guruceaga, Lara Grande, Jason T Huse, Maria A Aznar, Ricardo Díez-Valle, Sonia Tejada-Solís, Marta M Alonso, Jose L Fernandez-Luna, Jose A Martinez-Climent, Raquel Malumbres

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77098 (2013)

Glioblastoma multiforme (GBM)-initiating cells (GICs) represent a tumor subpopulation with neural stem cell-like properties that is responsible for the development, progression and therapeutic resistance of human GBM. We have recently shown that bloc

Externí odkaz: https://doaj.org/article/3b970be98d534179b7301ea28c969ea7

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Akademický článek

A novel pathway of TEF regulation mediated by microRNA-125b contributes to the control of actin distribution and cell shape in fibroblasts.

Autor: Olga Gutierrez, Maria T Berciano, Miguel Lafarga, Jose L Fernandez-Luna

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e17169 (2011)

BACKGROUND: Thyrotroph embryonic factor (TEF), a member of the PAR bZIP family of transcriptional regulators, has been involved in neurotransmitter homeostasis, amino acid metabolism, and regulation of apoptotic proteins. In spite of its relevance, n

Externí odkaz: https://doaj.org/article/d783498ff9c74786afa82b0f09ab5ffd

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Akademický článek

Osteomesopyknosis associated with a novel ALOX5 variant that impacts the RANKL pathway

Autor: Jose L. Fernandez‐Luna, José L. Hernández, Soraya Curiel‐Olmo, Néstor A. Martínez‐Amador, Ana I. Vega, Remedios Quirce, Santiago Montes‐Moreno, Olga Gutierrez, Alvaro delReal, Carolina Sañudo, Jose A. Riancho

Publikováno v: Molecular Genetics & Genomic Medicine, Vol 12, Iss 5, Pp n/a-n/a (2024)

Abstract Background Bone tissue homeostasis relies on the coordinated activity of the bone‐forming osteoblasts and bone‐resorbing osteoclasts. Osteomesopyknosis is considered a distinctive rare sclerosing skeletal disorder of unelucidated pathoph

Externí odkaz: https://doaj.org/article/333aa331f87e4ae59458c6e9b5707128

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Akademický článek

The Invasion Factor ODZ1 Is Upregulated through an Epidermal Growth Factor Receptor-Induced Pathway in Primary Glioblastoma Cells

Autor: Carlos Velasquez, Olga Gutierrez, Maria Carcelen, Jose L. Fernandez-Luna

Publikováno v: Cells, Vol 13, Iss 9, p 766 (2024)

We have previously shown that the transmembrane protein ODZ1 promotes cytoskeletal remodeling of glioblastoma (GBM) cells and invasion of the surrounding parenchyma through the activation of a RhoA–ROCK pathway. We also described that GBM cells can

Externí odkaz: https://doaj.org/article/aae400c7c10744e0a5b54cfb891afca8

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