Výsledky vyhledávání - "Jose L, Aceña"

Stereocontrolled Total Synthesis of (+)‐Altohyrtin A/Spongistatin 1

Autor: Ian Paterson, David Y.‐K. Chen, Mark J. Coster, Jose L. Aceña, Jordi Bach, Karl R. Gibson, Linda E. Keown, Renata M. Oballa, Thomas Trieselmann, Debra J. Wallace, Andrew P. Hodgson, Roger D. Norcross

Publikováno v: Angewandte Chemie. 113:4179-4184

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1f6e4eea8c1640679bf4d238cf7dae8
https://doi.org/10.1002/1521-3757(20011105)113:21<4179::aid-ange4179>3.0.co

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Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1 Financial support was provided by the EPSRC (GR/L41646), Cambridge Commonwealth Trust (Scholarship to M.J.C.), EC (Marie Curie Postdoctoral Fellowship to J.L.A.), DFG (Postdoctoral Fellowship to T.T.), NSERC-Canada (Postdoctoral Fellowship to R.M.O.), Churchill College (Research Fellowship to D.J.W.), Kingapos;s College and Sims Fund, Cambridge (Scholarship to D.Y.K.C.). We also thank Merck and AstraZeneca Pharmaceuticals for generous support, and Dr. Anne Butlin (AZ) and Dr. Nick Bampos (Cambridge) for valuable assistance

Autor: Ian, Paterson, David Y.-K., Chen, Mark J., Coster, Jose L., Aceña, Jordi, Bach, Karl R., Gibson, Linda E., Keown, Renata M., Oballa, Thomas, Trieselmann, Debra J., Wallace, Andrew P., Hodgson, Roger D., Norcross

Publikováno v: Angewandte Chemie (International ed. in English). 40(21)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::573baa738777e7c2d94da4cefbfc147e
https://pubmed.ncbi.nlm.nih.gov/12404491

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Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1

Autor: Ian, Paterson, David Y-K, Chen, Mark J, Coster, Jose L, Aceña, Jordi, Bach, Karl R, Gibson, Linda E, Keown, Renata M, Oballa, Thomas, Trieselmann, Debra J, Wallace, Andrew P, Hodgson, Roger D, Norcross

Publikováno v: Angewandte Chemie (International ed. in English). 40(21)

As an exceptionally potent antimitotic macrolide, altohyrtin A/spongistatin 1 shows great promise in cancer chemotherapy but its extreme scarcity in the natural sponges has halted its further preclinical development. A highly stereocontrolled total s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::52eb693919ccfc8eb7ec716919c3db2d
https://pubmed.ncbi.nlm.nih.gov/29712249

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