Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jose J. Rosado‐Franco"'
1
Akademický článek
Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier
Autor: Rodnie Colón Ortiz, Stephen Knerler, Lisa B. Fridman, Alicia Mercado, Amira-Storm Price, Jose J. Rosado-Franco, Hannah Wilkins, Bianca R. Flores, Benjamin C. Orsburn, Dionna W. Williams
Publikováno v: Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-27 (2024)
Abstract Background Appropriate interactions between antiretroviral therapies (ART) and drug transporters and metabolizing enzymes at the blood brain barrier (BBB) are critical to ensure adequate dosing of the brain to achieve HIV suppression. These
Externí odkaz: https://doaj.org/article/e4b502e6cecf445b9bae2fbc5aac1494
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2
Akademický článek
Outlining key inflammation‐associated parameters during early phase of an experimental gram‐negative sepsis model in rhesus macaques (Macaca mulatta)
Autor: Jose J. Rosado‐Franco, Marcos J. Ramos‐Benitez, Laura M. Parodi, Derick Rosario, Nicole Compo, Luis D. Giavedoni, Ana M. Espino
Publikováno v: Animal Models and Experimental Medicine, Vol 2, Iss 4, Pp 326-333 (2019)
Abstract The aim of this study was to identify inflammation‐associated markers during the early phase of sepsis in rhesus macaque. Four rhesus macaques were given an intravenous dose of 1010 CFU/kg of E. coli. Blood samples were collected before, o
Externí odkaz: https://doaj.org/article/bac2e43e05ed42d294bb5fb5f142d690
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3
Akademický článek
Recombinant Fasciola hepatica Fatty Acid Binding Protein as a Novel Anti-Inflammatory Biotherapeutic Drug in an Acute Gram-Negative Nonhuman Primate Sepsis Model
Autor: Jose J. Rosado-Franco, Albersy Armina-Rodriguez, Nicole Marzan-Rivera, Armando G. Burgos, Natalie Spiliopoulos, Stephanie M. Dorta-Estremera, Loyda B. Mendez, A. M. Espino
Publikováno v: Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT Due to their phylogenetic proximity to humans, nonhuman primates (NHPs) are considered an adequate choice for a basic and preclinical model of sepsis. Gram-negative bacteria are the primary causative of sepsis. During infection, bacteria con
Externí odkaz: https://doaj.org/article/1ee9e3d4f45c4d6e9644034c1774a442
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4
Akademický článek
Fh15 Blocks the Lipopolysaccharide-Induced Cytokine Storm While Modulating Peritoneal Macrophage Migration and CD38 Expression within Spleen Macrophages in a Mouse Model of Septic Shock
Autor: Marcos J. Ramos-Benitez, Caleb Ruiz-Jimenez, Jose J. Rosado-Franco, Willy D. Ramos-Pérez, Loyda B. Mendez, Antonio Osuna, Ana M. Espino
Publikováno v: mSphere, Vol 3, Iss 6 (2018)
ABSTRACT Sepsis caused by Gram-negative bacteria is the consequence of an unrestrained infection that continuously releases lipopolysaccharide (LPS) into the bloodstream, which triggers an uncontrolled systemic inflammatory response leading to multio
Externí odkaz: https://doaj.org/article/cef3d064ad834faaac6cd5b629a2ab13
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5
Outlining key inflammation‐associated parameters during early phase of an experimental gram‐negative sepsis model in rhesus macaques (Macaca mulatta)
Autor: Nicole R Compo, Luis D. Giavedoni, Marcos J Ramos-Benitez, Jose J. Rosado‐Franco, Laura M. Parodi, Derick Rosario, Ana M. Espino
Publikováno v: Animal Models and Experimental Medicine, Vol 2, Iss 4, Pp 326-333 (2019)
The aim of this study was to identify inflammation‐associated markers during the early phase of sepsis in rhesus macaque. Four rhesus macaques were given an intravenous dose of 1010 CFU/kg of E. coli. Blood samples were collected before, or 30 minu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0809d071fc415a7ed585cdd3a8d81dd
https://doaj.org/article/bac2e43e05ed42d294bb5fb5f142d690
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7
Recombinant Fasciola hepatica fatty acid binding protein (Fh15) as a novel anti-inflammatory biotherapeutic in an acute gram-negative non-human primate sepsis model
Autor: Ana M Espino, Jose J Rosado-Franco, Albersy Armina-Rodriguez, Nicole Marzan-Rivera, Armando G Burgos, Natalie Spiliopoulus, Loyda B Mendez
Publikováno v: The Journal of Immunology. 208:51.10-51.10
Due to their phylogenetic proximity to human, non-human primates are considered an adequate choice for basic and pre-clinical model of sepsis. Gram-negative bacteria are the primary causative of sepsis. During infection, bacteria continuously release
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b49cfc6edbe582d02e567d407a0b325c
https://doi.org/10.4049/jimmunol.208.supp.51.10
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8
Fh15 Blocks the Lipopolysaccharide-Induced Cytokine Storm While Modulating Peritoneal Macrophage Migration and CD38 Expression within Spleen Macrophages in a Mouse Model of Septic Shock
Autor: Caleb Ruiz-Jiménez, Ana M. Espino, Willy D. Ramos-Perez, Antonio Osuna, Marcos J Ramos-Benitez, Loyda B. Mendez, Jose J. Rosado-Franco
Publikováno v: mSphere, Vol 3, Iss 6, p e00548-18 (2018)
mSphere
mSphere, Vol 3, Iss 6 (2018)
Sepsis is a potentially life-threatening complication of an infection. Sepsis is mostly the consequence of systemic bacterial infections leading to exacerbated activation of immune cells by bacterial products, resulting in enhanced release of inflamm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf08684d038cc7040bcd744121df29f
https://doaj.org/article/cc714710d01a483e9f997181f4bc9089
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