Imidazole and Imidazolium Antibacterial Drugs Derived from Amino Acids

Autor: Adriana Valls, Jose J. Andreu, Eva Falomir, Santiago V. Luis, Elena Atrián-Blasco, Scott G. Mitchell, Belén Altava

Publikováno v: Pharmaceuticals, Vol 13, Iss 12, p 482 (2020)

The antibacterial activity of imidazole and imidazolium salts is highly dependent upon their lipophilicity, which can be tuned through the introduction of different hydrophobic substituents on the nitrogen atoms of the imidazole or imidazolium ring o

Externí odkaz: https://doaj.org/article/4f0e884c6c7b4c42b4eba731c7ba4afc

A tribute to Dr. Serge N. Timasheff, our mentor.

Autor: Aune K; 7647 Cortana Drive, Granger, IN 46530 USA., Lee J; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77059 USA., Prakash V; Nutraceuticals and Nutritional Research Center, Ramaiah University of Applied Sciences, Bangalore, India., Bhat R; School of Biotechnology, Jawaharalal Nehru University, New Delhi, 110067 India., Andreu J; Centro de Investigaciones Biológicas Margarita Salas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain., Monasterio O; Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Santiago, Chile., Perez-Ramirez B; CMC-Drug Device Integration, DP-Due Diligence, Biologics Drug Product Development & Manufacturing, Sanofi, 1 the Mountain Road, Framingham, MA 01701 USA., Shearwin K; Department of Molecular and Biomedical Science, School of Biological Sciences, The University of Adelaide, Adelaide, 5005 Australia., Arakawa T; Alliance Protein Laboratories, 13380 Pantera Road, San Diego, CA 92130 USA., Carpenter J; Department of Pharmaceutical Sciences, Center for Pharmaceutical Biotechnology, University of Colorado Anshutz Medical Campus, Auroa, CO 80045 USA., Crowe J; Department of Molecular and Cellular Biology, University of California, Davis, CA 95616 USA., Crowe L; Department of Molecular and Cellular Biology, University of California, Davis, CA 95616 USA., Somero G; Hopkins Marine Station, Stanford University, Pacific Grove, CA 93950 USA., Gagnon P; BIA Separations, Mirce 21, 5270, Ajdovscina, Slovenia., Charles MT; The Charles Group, LLC, 322 Massachusetts Ave. NE, Washington, DC USA.

Publikováno v: Biophysical reviews [Biophys Rev] 2021 Jul 06; Vol. 13 (4), pp. 459-484. Date of Electronic Publication: 2021 Jul 06 (Print Publication: 2021).