Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jose Ignacio Garzon"'
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004461 (2015)
Protein-protein interfaces have been evolutionarily-designed to enable transduction between the interacting proteins. Thus, we hypothesize that analysis of the dynamics of the complex can reveal details about the nature of the interaction, and in par
Externí odkaz:
https://doaj.org/article/3ff12170bc824125bfce94fcbdcfa0d3
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 5, p e1004248 (2015)
We describe a method to predict protein-protein interactions (PPIs) formed between structured domains and short peptide motifs. We take an integrative approach based on consensus patterns of known motifs in databases, structures of domain-motif compl
Externí odkaz:
https://doaj.org/article/894ded1395b44302ae8197901d301530
Publikováno v:
eLife, Vol 5 (2016)
We present a database, PrePPI (Predicting Protein-Protein Interactions), of more than 1.35 million predicted protein-protein interactions (PPIs). Of these at least 127,000 are expected to constitute direct physical interactions although the actual nu
Externí odkaz:
https://doaj.org/article/f89e7a154b88446d80f3afa2470caad7
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89466 (2014)
The distance-dependent knowledge-based DrugScore(PPI) potentials, previously developed for in silico alanine scanning and hot spot prediction on given structures of protein-protein complexes, are evaluated as a scoring and objective function for the
Externí odkaz:
https://doaj.org/article/82ab4e5a13144034b0ab0806efa2c1b5