Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jose I. Pueyo"'
Autor:
Jose I. Pueyo, Jorge Salazar, Carolina Grincho, Jimena Berni, Benjamin P. Towler, Sarah F. Newbury
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Recent advances in proteogenomic techniques and bioinformatic pipelines have permitted the detection of thousands of translated small Open Reading Frames (smORFs), which contain less than 100 codons, in eukaryotic genomes. Hundreds of these actively
Externí odkaz:
https://doaj.org/article/be316e1f25814526bb4e696953c8b099
Autor:
Emile G. Magny, Ana Isabel Platero, Sarah A. Bishop, Jose I. Pueyo, Daniel Aguilar-Hidalgo, Juan Pablo Couso
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Short open reading frames (smORFs) of less than 100 codons exist in the thousands in metazoan genomes, mostly with yet unknown functions. Here the authors show how a smORF conserved from flies to vertebrates produces a secreted peptide that enhances
Externí odkaz:
https://doaj.org/article/7f17f13f747943899fbf04ba7e53500e
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Translation of 100 to 300 micropeptides from small ORFs within lncRNA was detected by Ribosomal Profiling in Drosophila embryos. These translated small ORFs showed natural selection conserving micropeptide sequence and function.
Externí odkaz:
https://doaj.org/article/5a40e3f904794cdcad53ae9b2f86edeb