Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jose G. Pichel"'
Publikováno v:
Airway Pharmacology and Treatment.
Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, mucus overproduction and airway wall remodeling, affecting people from childhood to old age. House dust mite (HDM)-derived allergens, and specifically those arising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d01a94d57689811b480315fdc8f9b0
https://doi.org/10.1183/23120541.lungscienceconference-2019.pp204
https://doi.org/10.1183/23120541.lungscienceconference-2019.pp204
Autor:
Patricia Pérez-Matute, Icíar P. López, María Íñiguez, Emma Recio-Fernández, Raquel Torrens, Sergio Piñeiro-Hermida, Elvira Alfaro-Arnedo, Luong Chau, Christina Walz, Andreas Hoeflich, José A. Oteo, José G. Pichel
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveWe aimed to investigate the short and long-term metabolic consequences of IGF1R systemic gene deficiency in mice.MethodsUBC-CreERT2, Igf1rfl/fl mutant mice were used to suppress IGF1R signaling in adult tissues by inducing postnatal generali
Externí odkaz:
https://doaj.org/article/d487c97cd50643339ffa6225129c7e2c
Autor:
Elvira Alfaro-Arnedo, Icíar P. López, Sergio Piñeiro-Hermida, Álvaro C. Ucero, Francisco J. González-Barcala, Francisco J. Salgado, José G. Pichel
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 733 (2022)
In the original article [...]
Externí odkaz:
https://doaj.org/article/69a94a3ae23a4e8cb2a0229ed47bc2b4
Autor:
Elvira Alfaro-Arnedo, Icíar P. López, Sergio Piñeiro-Hermida, Álvaro C. Ucero, Francisco J. González-Barcala, Francisco J. Salgado, José G. Pichel
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 912 (2021)
Background: Asthma is a chronic lung disease characterized by reversible airflow obstruction, airway hyperresponsiveness (AHR), mucus overproduction and inflammation. Although Insulin-like growth factor 1 receptor (IGF1R) was found to be involved in
Externí odkaz:
https://doaj.org/article/6f9f70010fbb421d90ef8f772e6d3392
Autor:
Sergio Piñeiro-Hermida, Icíar P. López, Elvira Alfaro-Arnedo, Raquel Torrens, María Iñiguez, Lydia Alvarez-Erviti, Carlos Ruíz-Martínez, José G. Pichel
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract IGF1R (Insulin-like Growth Factor 1 Receptor) is a tyrosine kinase with pleiotropic cellular functions. IGF activity maintains human lung homeostasis and is implicated in pulmonary diseases such as cancer, ARDS, COPD, asthma and fibrosis. He
Externí odkaz:
https://doaj.org/article/3b2793cee94e4995ba43123296da8895
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 158 (2021)
Insulin-like growth factor 1 receptor (IGF1R)-mediated signaling pathways modulate important neurophysiological aspects in the central nervous system, including neurogenesis, synaptic plasticity and complex cognitive functions. In the present study,
Externí odkaz:
https://doaj.org/article/84a1c691874c4ff0adbca7b20d893917
Autor:
Hortensia Sanchez-Calderon, Lourdes Rodriguez-de la Rosa, Marta Milo, Jose G Pichel, Matthew Holley, Isabel Varela-Nieto
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8699 (2010)
Insulin-like growth factor-I (IGF-I) provides pivotal cell survival and differentiation signals during inner ear development throughout evolution. Homozygous mutations of human IGF1 cause syndromic sensorineural deafness, decreased intrauterine and p
Externí odkaz:
https://doaj.org/article/1456aac919f648adb399875fb6be0ecf