Another Whipple’s triad? Pericardial, myocardial and valvular disease in an unusual case presentation from a Canadian perspective

Autor: Christina S. Thornton, Yinong Wang, Martin Köebel, Kathryn Bernard, Tamara Burdz, Andrew Maitland, Jose G. Ferraz, Paul L. Beck, Andre Ferland

Publikováno v: BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-8 (2019)

Abstract Background Whipple’s disease is a clinically relevant multi-system disorder that is often undiagnosed given its elusive nature. We present an atypical case of Whipple’s disease involving pan-valvular endocarditis and constrictive pericar

Externí odkaz: https://doaj.org/article/6d327786762b46f7baedebe284544a82

Artificial Intelligence Enabled Histological Prediction of Remission or Activity and Clinical Outcomes in Ulcerative Colitis

Autor: Marietta Iacucci, Tommaso Lorenzo Parigi, Rocio Del Amor, Pablo Meseguer, Giulio Mandelli, Anna Bozzola, Alina Bazarova, Pradeep Bhandari, Raf Bisschops, Silvio Danese, Gert De Hertogh, Jose G. Ferraz, Martin Goetz, Enrico Grisan, Xianyong Gui, Bu Hayee, Ralf Kiesslich, Mark Lazarev, Remo Panaccione, Adolfo Parra-Blanco, Luca Pastorelli, Timo Rath, Elin S. Røyset, Gian Eugenio Tontini, Michael Vieth, Davide Zardo, Subrata Ghosh, Valery Naranjo, Vincenzo Villanacci

BACKGROUND & AIMS: Microscopic inflammation has significant prognostic value in ulcerative colitis (UC); however, its assessment is complex with high interobserver variability. We aimed to develop and validate an artificial intelligence (AI) computer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc381a7ad84dae8134cd866fc2a07b02
https://lirias.kuleuven.be/handle/20.500.12942/716447

Constrained multiple instance learning for ulcerative colitis prediction using histological images

Autor: Rocío del Amor, Pablo Meseguer, Tommaso Lorenzo Parigi, Vincenzo Villanacci, Adrián Colomer, Laëtitia Launet, Alina Bazarova, Gian Eugenio Tontini, Raf Bisschops, Gert de Hertogh, Jose G. Ferraz, Martin Götz, Xianyong Gui, Bu’Hussain Hayee, Mark Lazarev, Remo Panaccione, Adolfo Parra-Blanco, Pradeep Bhandari, Luca Pastorelli, Timo Rath, Elin Synnøve Røyset, Michael Vieth, Davide Zardo, Enrico Grisan, Subrata Ghosh, Marietta Iacucci, Valery Naranjo

[EN] Background and Objective: Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) affecting the colon and the rectum characterized by a remitting-relapsing course. To detect mucosal inflammation as-sociated with UC, histology is considere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255f8167c06e67a2271abb399fb38eb7
https://hdl.handle.net/2434/962506

Revisiting the distinct histomorphologic features of inflammatory bowel disease–associated neoplastic precursor lesions in the SCENIC and post–DALM Era

Autor: Scott D. Lee, Marietta Iacucci, Jose G. Ferraz, Subrata Ghosh, Xianyong Gui

Publikováno v: Human Pathology. 100:24-37

Summary Distinct histomorphologic features of colitis-associated dysplasia (CAD) or neoplastic precursors in inflammatory bowel disease (IBD) have never been clearly identified. In this study, we tried to further explore the differentiating morpholog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35daf61ac1259fc8df5c7786b9f40135
https://doi.org/10.1016/j.humpath.2020.04.010

Perturbed Mitochondrial Dynamics Is a Novel Feature of Colitis That Can Be Targeted to Lessen DiseaseSummary

Autor: Rasha Sabouny, Nicolas Esquerre, Derek M. McKay, Nicole L. Mancini, Yasmin Nasser, Timothy E. Shutt, Jane Shearer, Sruthi Rajeev, Warren J. Xu, Erik van Tilburg Bernandes, Ala Al Rajabi, Jose G. Ferraz, Timothy S. Jayme, Arthur Wang, Luke J. L. Goudie

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 287-307 (2020)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Mitochondria exist in a constantly remodelling network, and excessive fragmentation can be pathophysiological. Mitochondrial dysfunction can accompany enteric inflammation, but any contribution of altered mitochondrial dynamics (ie,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc08ce7c90989ef3a6199a0f6b24ffa
http://www.sciencedirect.com/science/article/pii/S2352345X20300485