Clinical outcomes in patients with chronic lymphocytic leukemia with disease progression on ibrutinib

Autor: Paul J. Hampel, Kari G. Rabe, Timothy G. Call, Wei Ding, Jose F. Leis, Asher A. Chanan-Khan, Saad S. Kenderian, Eli Muchtar, Yucai Wang, Sikander Ailawadhi, Amber B. Koehler, Ricardo Parrondo, Susan M. Schwager, Taimur Sher, Curtis A. Hanson, Min Shi, Daniel L. Van Dyke, Esteban Braggio, Susan L. Slager, Neil E. Kay, Sameer A. Parikh

Publikováno v: Blood Cancer Journal, Vol 12, Iss 9, Pp 1-6 (2022)

Abstract Patients with chronic lymphocytic leukemia (CLL) with disease progression on ibrutinib have worse outcomes compared to patients stopping ibrutinib due to toxicity. A better understanding of expected outcomes in these patients is necessary to

Externí odkaz: https://doaj.org/article/c5ee38417b3b4e7f8218d469cd1ba54f

Cause of death in patients with newly diagnosed chronic lymphocytic leukemia (CLL) stratified by the CLL-International Prognostic Index

Autor: Yucai Wang, Sara J. Achenbach, Kari G. Rabe, Tait D. Shanafelt, Timothy G. Call, Wei Ding, Saad S. Kenderian, Eli Muchtar, Jose F. Leis, Amber B. Koehler, Susan M. Schwager, James R. Cerhan, Susan L. Slager, Neil E. Kay, Sameer A. Parikh

Publikováno v: Blood Cancer Journal, Vol 11, Iss 8, Pp 1-4 (2021)

Externí odkaz: https://doaj.org/article/863bb1613c0f4313b4f20f6c1c59d34d

Venetoclax treatment of patients with relapsed T-cell prolymphocytic leukemia

Autor: Paul J. Hampel, Sameer A. Parikh, Timothy G. Call, Mithun V. Shah, N. Nora Bennani, Aref Al-Kali, Kari G. Rabe, Yucai Wang, Eli Muchtar, Jose F. Leis, Saad S. Kenderian, Amber B. Koehler, Susan M. Schwager, Susan L. Slager, Neil E. Kay, Curtis A. Hanson, Daniel L. Van Dyke, Min Shi, Wei Ding

Publikováno v: Blood Cancer Journal, Vol 11, Iss 3, Pp 1-6 (2021)

Externí odkaz: https://doaj.org/article/5034355e2436472d9133161b489aabbc

Clinical characteristics and outcomes of Richter transformation: experience of 204 patients from a single center

Autor: Yucai Wang, Marcella A. Tschautscher, Kari G. Rabe, Timothy G. Call, Jose F. Leis, Saad S. Kenderian, Neil E. Kay, Eli Muchtar, Daniel L. Van Dyke, Amber B. Koehler, Susan M. Schwager, Susan L. Slager, Sameer A. Parikh, Wei Ding

Publikováno v: Haematologica, Vol 105, Iss 3 (2020)

The natural history, prognostication and optimal treatment of Richter transformation developed from chronic lymphocytic leukemia (CLL) are not well defined. We report the clinical characteristics and outcomes of a large series of biopsy-confirmed Ric

Externí odkaz: https://doaj.org/article/0a28ead1701247398d3622a34a0b481c

Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia

Autor: Sonja I. Berndt, Nicola J. Camp, Christine F. Skibola, Joseph Vijai, Zhaoming Wang, Jian Gu, Alexandra Nieters, Rachel S. Kelly, Karin E. Smedby, Alain Monnereau, Wendy Cozen, Angela Cox, Sophia S. Wang, Qing Lan, Lauren R. Teras, Moara Machado, Meredith Yeager, Angela R. Brooks-Wilson, Patricia Hartge, Mark P. Purdue, Brenda M. Birmann, Claire M. Vajdic, Pierluigi Cocco, Yawei Zhang, Graham G. Giles, Anne Zeleniuch-Jacquotte, Charles Lawrence, Rebecca Montalvan, Laurie Burdett, Amy Hutchinson, Yuanqing Ye, Timothy G. Call, Tait D. Shanafelt, Anne J. Novak, Neil E. Kay, Mark Liebow, Julie M. Cunningham, Cristine Allmer, Henrik Hjalgrim, Hans-Olov Adami, Mads Melbye, Bengt Glimelius, Ellen T. Chang, Martha Glenn, Karen Curtin, Lisa A. Cannon-Albright, W Ryan Diver, Brian K. Link, George J. Weiner, Lucia Conde, Paige M. Bracci, Jacques Riby, Donna K. Arnett, Degui Zhi, Justin M. Leach, Elizabeth A. Holly, Rebecca D. Jackson, Lesley F. Tinker, Yolanda Benavente, Núria Sala, Delphine Casabonne, Nikolaus Becker, Paolo Boffetta, Paul Brennan, Lenka Foretova, Marc Maynadie, James McKay, Anthony Staines, Kari G. Chaffee, Sara J. Achenbach, Celine M. Vachon, Lynn R. Goldin, Sara S. Strom, Jose F. Leis, J. Brice Weinberg, Neil E. Caporaso, Aaron D. Norman, Anneclaire J. De Roos, Lindsay M. Morton, Richard K. Severson, Elio Riboli, Paolo Vineis, Rudolph Kaaks, Giovanna Masala, Elisabete Weiderpass, María- Dolores Chirlaque, Roel C. H. Vermeulen, Ruth C. Travis, Melissa C. Southey, Roger L. Milne, Demetrius Albanes, Jarmo Virtamo, Stephanie Weinstein, Jacqueline Clavel, Tongzhang Zheng, Theodore R. Holford, Danylo J. Villano, Ann Maria, John J. Spinelli, Randy D. Gascoyne, Joseph M. Connors, Kimberly A. Bertrand, Edward Giovannucci, Peter Kraft, Anne Kricker, Jenny Turner, Maria Grazia Ennas, Giovanni M. Ferri, Lucia Miligi, Liming Liang, Baoshan Ma, Jinyan Huang, Simon Crouch, Ju-Hyun Park, Nilanjan Chatterjee, Kari E. North, John A. Snowden, Josh Wright, Joseph F. Fraumeni, Kenneth Offit, Xifeng Wu, Silvia de Sanjose, James R. Cerhan, Stephen J. Chanock, Nathaniel Rothman, Susan L. Slager

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)

Chronic lymphocytic leukemia is a highly inheritable cancer. Here the authors conduct a metaanalysis of four genome-wide association studies and identify three novel loci located near EOMES, SERPINB6 and LPPassociated with risk of this disease.

Externí odkaz: https://doaj.org/article/291f7f66c64e40539e0a55a7e9fcad49