Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jose F Tort"'
Autor:
Samantha N McNulty, Jose F Tort, Gabriel Rinaldi, Kerstin Fischer, Bruce A Rosa, Pablo Smircich, Santiago Fontenla, Young-Jun Choi, Rahul Tyagi, Kymberlie Hallsworth-Pepin, Victoria H Mann, Lakshmi Kammili, Patricia S Latham, Nicolas Dell'Oca, Fernanda Dominguez, Carlos Carmona, Peter U Fischer, Paul J Brindley, Makedonka Mitreva
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006537 (2017)
Food borne trematodes (FBTs) are an assemblage of platyhelminth parasites transmitted through the food chain, four of which are recognized as neglected tropical diseases (NTDs). Fascioliasis stands out among the other NTDs due to its broad and signif
Externí odkaz:
https://doaj.org/article/883fbd5b5c5b4000bf2b0b4b8bee7375
Autor:
Mark W Robinson, Ileana Corvo, Peter M Jones, Anthony M George, Matthew P Padula, Joyce To, Martin Cancela, Gabriel Rinaldi, Jose F Tort, Leda Roche, John P Dalton
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 4, p e1012 (2011)
BACKGROUND: The temporal expression and secretion of distinct members of a family of virulence-associated cathepsin L cysteine peptidases (FhCL) correlates with the entry and migration of the helminth pathogen Fasciola hepatica in the host. Thus, inf
Externí odkaz:
https://doaj.org/article/0d9f9991408b4538968d958192283b3b
Autor:
Kristine J Kines, Gabriel Rinaldi, Tunika I Okatcha, Maria E Morales, Victoria H Mann, Jose F Tort, Paul J Brindley
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 2, p e593 (2010)
The schistosome egg represents an attractive developmental stage at which to target transgenes because of the high ratio of germ to somatic cells, because the transgene might be propagated and amplified by infecting snails with the miracidia hatched
Externí odkaz:
https://doaj.org/article/ad040f3d25b3491994cec251cfbf6614
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Platyhelminthes comprise one of the major phyla of invertebrate animals, inhabiting a wide range of ecosystems, and one of the most successful in adapting to parasitic life. Small non-coding RNAs have been implicated in regulating complex development
Externí odkaz:
https://doaj.org/article/b991dd07f5fc4526a159ee746319011c
Publikováno v:
BMC Evolutionary Biology, Vol 17, Iss 1, Pp 1-16 (2017)
Abstract Background Small non-coding RNAs, including miRNAs, and gene silencing mediated by RNA interference have been described in free-living and parasitic lineages of flatworms, but only few key factors of the small RNA pathways have been exhausti
Externí odkaz:
https://doaj.org/article/80afd1ba185749b3ad312d8584d51185
Publikováno v:
Frontiers in Genetics
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Frontiers in Genetics
COLIBRI
Universidad de la República
instacron:Universidad de la República
Frontiers in Genetics
COLIBRI
Universidad de la República
instacron:Universidad de la República
In the present work, we performed a comparative genome-wide analysis of 22 species representative of the main clades and lifestyles of the phylum Platyhelminthes. We selected a set of 700 orthologous genes conserved in all species, measuring changes
Autor:
Mark W, Robinson, Jose F, Tort, Jonathan, Lowther, Sheila M, Donnelly, Emily, Wong, Weibo, Xu, Colin M, Stack, Matthew, Padula, Ben, Herbert, John P, Dalton
Publikováno v:
Molecularcellular proteomics : MCP. 7(6)
Cathepsin L proteases secreted by the helminth pathogen Fasciola hepatica have functions in parasite virulence including tissue invasion and suppression of host immune responses. Using proteomics methods alongside phylogenetic studies we characterize
Autor:
Florencia Ferraro, Alicia Merlino, Nicolás Dell Oca, Jorge Gil, José F Tort, Mercedes Gonzalez, Hugo Cerecetto, Mauricio Cabrera, Ileana Corvo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 7, p e0004834 (2016)
BACKGROUND:Increased reports of human infections have led fasciolosis, a widespread disease of cattle and sheep caused by the liver flukes Fasciola hepatica and Fasciola gigantica, to be considered an emerging zoonotic disease. Chemotherapy is the ma
Externí odkaz:
https://doaj.org/article/197bc4fb1d214adea06d347bbb8c494a
Autor:
Ileana Corvo, Anthony J O'Donoghue, Lucía Pastro, Natalia Pi-Denis, Alegra Eroy-Reveles, Leda Roche, James H McKerrow, John P Dalton, Charles S Craik, Conor R Caffrey, José F Tort
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2269 (2013)
A family of secreted cathepsin L proteases with differential activities is essential for host colonization and survival in the parasitic flatworm Fasciola hepatica. While the blood feeding adult secretes predominantly FheCL1, an enzyme with a strong
Externí odkaz:
https://doaj.org/article/39e3cf915bba40f283c68f81e3d26e2e