Red deer in Iberia: Molecular ecological studies in a southern refugium and inferences on European postglacial colonization history.

Autor: João Queirós, Pelayo Acevedo, João P V Santos, Jose Barasona, Beatriz Beltran-Beck, David González-Barrio, Jose A Armenteros, Iratxe Diez-Delgado, Mariana Boadella, Isabel Fernandéz de Mera, Jose F Ruiz-Fons, Joaquin Vicente, Jose de la Fuente, Christian Gortázar, Jeremy B Searle, Paulo C Alves

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210282 (2019)

The red deer (Cervus elaphus) is a widespread wild ungulate in Europe that has suffered strong anthropogenic impacts over their distribution during the last centuries, but also at the present time, due its economic importance as a game species. Here

Externí odkaz: https://doaj.org/article/6caf22cdf15f4841ac5c09449fd25446

Yeast pol4 promotes tel1-regulated chromosomal translocations.

Autor: Jose F Ruiz, Benjamin Pardo, Guillermo Sastre-Moreno, Andrés Aguilera, Luis Blanco

Publikováno v: PLoS Genetics, Vol 9, Iss 7, p e1003656 (2013)

DNA double-strand breaks (DSBs) are one of the most dangerous DNA lesions, since their erroneous repair by nonhomologous end-joining (NHEJ) can generate harmful chromosomal rearrangements. PolX DNA polymerases are well suited to extend DSB ends that

Externí odkaz: https://doaj.org/article/860063a05b7e4982a79cba0b6bea4824

'An end to a means': How DNA-end structure shapes the double-strand break repair process

Autor: Almudena Serrano-Benítez, Felipe Cortés-Ledesma, Jose F. Ruiz

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Molecular Biosciences, Vol 6 (2020)
idUS. Depósito de Investigación de la Universidad de Sevilla
Frontiers in Molecular Biosciences

Endogenously-arising DNA double-strand breaks (DSBs) rarely harbor canonical 5′-phosphate, 3′-hydroxyl moieties at the ends, which are, regardless of the pathway used, ultimately required for their repair. Cells are therefore endowed with a wide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f742c55a401e087f2188a8a756cac0b
http://hdl.handle.net/10261/221222

miR-181a negatively regulates NF-κB signaling and affects activated B-cell-like diffuse large B-cell lymphoma pathogenesis

Autor: Ari Melnick, Shruti Bhatt, Xiaoyu Jiang, Goldi A. Kozloski, Francisco Vega, Rita Shaknovich, Jose F. Ruiz, Izidore S. Lossos

Publikováno v: Blood. 127(23)

Distinct subgroups of diffuse large B-cell lymphoma (DLBCL) genetically resemble specific mature B-cell populations that are blocked at different stages of the immune response in germinal centers (GCs). The activated B-cell (ABC)-like subgroup resemb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa227ec3c407cdce104306d04773a4c
https://pubmed.ncbi.nlm.nih.gov/27282943

Tissue Factor Pathway Inhibitor Inhibits Endothelial Cell Proliferation via Association with the Very Low Density Lipoprotein Receptor

Autor: Dudley K. Strickland, Adonia E. Papathanassiu, Todd Hembrough, Jose F. Ruiz, Shawn J. Green

Publikováno v: Journal of Biological Chemistry. 276:12241-12248

Tissue factor pathway inhibitor (TFPI) contains three Kunitz-type proteinase inhibitor domains and is a potent inhibitor of tissue factor-mediated coagulation. Here, we report that TFPI inhibits the proliferation of basic fibroblast growth factor-sti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a24cbb7819fe12e62c7ec469df0abd
https://doi.org/10.1074/jbc.m010395200