Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Jose F Abisambra"'
Autor:
Adam D Bachstetter, Zhengqiu Zhou, Rachel K Rowe, Bin Xing, Danielle S Goulding, Alyssa N Conley, Pradoldej Sompol, Shelby Meier, Jose F Abisambra, Jonathan Lifshitz, D Martin Watterson, Linda J Van Eldik
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149451 (2016)
A prevailing neuroinflammation hypothesis is that increased production of proinflammatory cytokines contributes to progressive neuropathology, secondary to the primary damage caused by a traumatic brain injury (TBI). In support of the hypothesis, pos
Externí odkaz:
https://doaj.org/article/32ab32dac3e442338effa09f838c073e
Autor:
Jose F Abisambra, Tina Fiorelli, Jaya Padmanabhan, Peter Neame, Inge Wefes, Huntington Potter
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8556 (2010)
BACKGROUND: Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most common form of dementia. The major molecular risk factor for late-onset AD is expression of the epsilon-4 allele of apolipoprotein E (apoE), the major cholester
Externí odkaz:
https://doaj.org/article/21c355055680449696141c40328db022
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Manganese-enhanced magnetic resonance imaging (MEMRI) rose to prominence in the 1990s as a sensitive approach to high contrast imaging. Following the discovery of manganese conductance through calcium-permeable channels, MEMRI applications expanded t
Externí odkaz:
https://doaj.org/article/177627fde7ab4249b8b37f0a727c3d83
Autor:
Samantha M. Smith, Elena L. Garcia, Caroline Davidson, John Thompson, Sarah Lovett, Nedi Ferekides, Quinten Federico, Argyle V. Bumanglag, Abbi R. Hernandez, Jose F. Abisambra, Sara N. Burke
Publikováno v:
Behav Brain Res
Approximately 60-70 million people suffer from traumatic brain injury (TBI) each year. Animal models continue to be paramount in understanding mechanisms of cellular dysfunction and testing new treatments for TBI. Enhancing the translational potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1311c06d57c8b0485ba6f61c218c0634
https://europepmc.org/articles/PMC9927580/
https://europepmc.org/articles/PMC9927580/
Autor:
Tharick A. Pascoal, Julyanna A. Peny, Elisa de Paula França Resende, Érica Leandro Marciano Vieira, Natalia M. Lyra e Silva, Isadora C. Furigo, Julia R. Clarke, Ricardo A.S. Lima-Filho, Antônio Lúcio Teixeira, Beatriz M. Longo, Pedro Rosa-Neto, Debora Hashiguchi, Jose Donato, Juliana T.S. Fortuna, Vivian S. Miya-Coreixas, Paulo Caramelli, Paul E. Fraser, Fernanda G. De Felice, Rafaella Araujo Gonçalves, Leonardo Cruz de Souza, Jose F. Abisambra, Sergio T. Ferreira
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Translational Psychiatry
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Translational Psychiatry
Alzheimer’s disease (AD) is associated with memory impairment and altered peripheral metabolism. Mounting evidence indicates that abnormal signaling in a brain-periphery metabolic axis plays a role in AD pathophysiology. The activation of pro-infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0aa36a51f417a787b71c8e35af6b79a
https://doaj.org/article/17556201da0949e79e2b1a92c14e9d0c
https://doaj.org/article/17556201da0949e79e2b1a92c14e9d0c
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3524 (2019)
Impairments in translation have been increasingly implicated in the pathogenesis and progression of multiple neurodegenerative diseases. Assessing the spatiotemporal dynamics of translation in the context of disease is a major challenge. Recent devel
Externí odkaz:
https://doaj.org/article/30e242fbe9c34d429ffa442e763596d7
Autor:
Grant K. Nation, Orsolya Huzian, Jenna L. Gollihue, László G. Puskás, László Hackler, Miklós Sántha, Ryan Cloyd, Jose F. Abisambra, Lajos Nagy, Irina A. Artiushin, Susan D. Kraner, Christopher M. Norris, Shon A. Koren, Emad Chishti, Pradoldej Sompol
Publikováno v:
Aging Cell
Inhibition of the protein phosphatase calcineurin (CN) ameliorates pathophysiologic and cognitive changes in aging rodents and mice with aging‐related Alzheimer's disease (AD)‐like pathology. However, concerns over adverse effects have slowed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5b07b0e447474c18192a586f30dcae
https://doi.org/10.1111/acel.13416
https://doi.org/10.1111/acel.13416
Autor:
Shelby E. Meier, Jing Chen, Jose F. Abisambra, Juan Pablo Arango, Haining Zhu, Grant K. Nation, Matthew Hamm, Eric M. Blalock, Blaine E. Weiss, Emad Chishti, Shon A. Koren
Publikováno v:
Acta Neuropathologica
There is a fundamental gap in understanding the consequences of tau–ribosome interactions. Tau oligomers and filaments hinder protein synthesis in vitro, and they associate strongly with ribosomes in vivo. Here, we investigated the consequences of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148baa4985772d38bc64ee10a13c58c0
https://doi.org/10.1007/s00401-019-01970-9
https://doi.org/10.1007/s00401-019-01970-9
Autor:
Jennifer Rodriguez-Rivera, Shon A. Koren, Moriel H. Vandsburger, Tal Frolinger, Anika M.S. Hartz, Fabio Di Domenico, Emad Chishti, Chiara Lanzillotta, Ryan Cloyd, Jeffrey M. Axten, Matthew Hamm, Duc M. Duong, Alexandria Ingram, Nicholas Zulia, Nicholas J. Laping, Sarah N. Fontaine, John Koren, David K. Powell, Sara Galvis-Escobar, Nicholas T. Seyfried, Jose F. Abisambra, Michelle C. Bell
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1186, p 1186 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences
Volume 22
Issue 3
Tauopathies are a group of more than twenty known disorders that involve progressive neurodegeneration, cognitive decline and pathological tau accumulation. Current therapeutic strategies provide only limited, late-stage symptomatic treatment. This i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c960a4262eb4b59198d01489c573a158
https://www.mdpi.com/1422-0067/22/3/1186
https://www.mdpi.com/1422-0067/22/3/1186
Autor:
Marzia Perluigi, Chiara Lanzillotta, Fabio Di Domenico, D. Allan Butterfield, Carla Blarzino, Eugenio Barone, Matteo Caforio, Ilaria Zuliani, Jose F. Abisambra, Diletta Valentini, Alberto Villani, Franco Locatelli, Valentina Folgiero, Antonella Tramutola, Elizabeth Head
A major challenge in neurobiology is the identification of the mechanisms by which protein misfolding leads to cellular toxicity. Many neurodegenerative disorders, in which aberrant protein conformers aggregate into pathological inclusions, present t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c3bcb6454ce6d53361330bf28f9f4e
https://hdl.handle.net/10807/229516
https://hdl.handle.net/10807/229516