Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jose E. Perez-Ortin"'
Autor:
Shiladitya Chattopadhyay, Jose Garcia-Martinez, Gal Haimovich, Jonathan Fischer, Aya Khwaja, Oren Barkai, Silvia Gabriela Chuartzman, Maya Schuldiner, Ron Elran, Miriam I. Rosenberg, Shira Urim, Shubham Deshmukh, Katherine E. Bohnsack, Markus T. Bohnsack, Jose E. Perez-Ortin, Mordechai Choder
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Nucleocytoplasmic shuttling of several yeast mRNA decay factors regulates transcription and initiates a novel mRNA decay pathway; shuttling is controlled by the decaying RNA and is critical for coping with environmental changes.
Externí odkaz:
https://doaj.org/article/76e659328ff74fa9b932927ad681792b
Autor:
Shiladitya Chattopadhyay, Jose Garcia-Martinez, Gal Haimovich, Jonathan Fischer, Aya Khwaja, Oren Barkai, Silvia Gabriela Chuartzman, Maya Schuldiner, Ron Elran, Miriam I. Rosenberg, Shira Urim, Shubham Deshmukh, Katherine E. Bohnsack, Markus T. Bohnsack, Jose E. Perez-Ortin, Mordechai Choder
Publikováno v:
Chattopadhyay, Shiladitya García Martínez, José Haimovich, G. Fischer, Jonathan Khwaja, Aya Barkai, O. Chuartzman, Silvia Gabriela Schuldiner, Maya Elran, Ron Rosenberg, Miriam I. Urim, Shira Deshmukh, Shubham Bohnsack, Katherine E. Bohnsack, Markus T. Pérez Ortín, José Enrique Choder, M. 2022 RNA-controlled nucleocytoplasmic shuttling of mRNA decay factors regulates mRNA synthesis and a novel mRNA decay pathway Nature Communications 13 7184 1 17
mRNA level is controlled by factors that mediate both mRNA synthesis and decay, including the 5’ to 3’ exonuclease Xrn1. Here we show that nucleocytoplasmic shuttling of several yeast mRNA decay factors plays a key role in determining both mRNA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a2620028081e048d56cbcd53bf2cd5
https://pubmed.ncbi.nlm.nih.gov/36418294
https://pubmed.ncbi.nlm.nih.gov/36418294
Autor:
Bernat Blasco-Moreno, Leire de Campos-Mata, René Böttcher, José García-Martínez, Jennifer Jungfleisch, Danny D. Nedialkova, Shiladitya Chattopadhyay, María-Eugenia Gas, Baldomero Oliva, José E. Pérez-Ortín, Sebastian A. Leidel, Mordechai Choder, Juana Díez
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The exonuclease Xrn1 mediates crosstalk between transcription and mRNA decay in yeast. Here the authors demonstrate that Xrn1 promotes translation of mRNAs encoding membrane proteins, coupling transcription, translation, and mRNA decay.
Externí odkaz:
https://doaj.org/article/aa2f9afce7424f7ba3c5864b73c1260c
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
In eukaryotic cells, three nuclear RNA polymerases (RNA pols) carry out the transcription from DNA to RNA, and they all seem to have evolved from a single enzyme present in the common ancestor with archaea. The multiplicity of eukaryotic RNA pols all
Externí odkaz:
https://doaj.org/article/e58d9e66c7ab43cb8346b8fc1f659014
Autor:
Varinia García-Molinero, José García-Martínez, Rohit Reja, Pedro Furió-Tarí, Oreto Antúnez, Vinesh Vinayachandran, Ana Conesa, B. Franklin Pugh, José E. Pérez-Ortín, Susana Rodríguez-Navarro
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background Eukaryotic transcription is regulated through two complexes, the general transcription factor IID (TFIID) and the coactivator Spt–Ada–Gcn5 acetyltransferase (SAGA). Recent findings confirm that both TFIID and SAGA contribute t
Externí odkaz:
https://doaj.org/article/906169598c294a66841f677a6f77a193
Autor:
Gabriel Gutiérrez, Gonzalo Millán-Zambrano, Daniel A. Medina, Antonio Jordán-Pla, José E. Pérez-Ortín, Xenia Peñate, Sebastián Chávez
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-22 (2017)
Abstract Background TFIIS stimulates RNA cleavage by RNA polymerase II and promotes the resolution of backtracking events. TFIIS acts in the chromatin context, but its contribution to the chromatin landscape has not yet been investigated. Co-transcri
Externí odkaz:
https://doaj.org/article/a75964c5818b48a08a08fdeaceb7a80e
Publikováno v:
Cells, Vol 10, Iss 2, p 334 (2021)
The ultimate goal of gene expression regulation is on the protein level. However, because the amounts of mRNAs and proteins are controlled by their synthesis and degradation rates, the cellular amount of a given protein can be attained by following d
Externí odkaz:
https://doaj.org/article/1d7834927b6c43c5b0fcaa72b2268f93