New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab

Autor: Friedemann Paul, Angel Perez-Sempere, Oscar Fernandez, Alicia Laroni, Miguel A Hernández, Domingo Pérez, Matteo Gastaldi, Susana Sainz de la Maza, Guillermo Izquierdo, Mercedes Espiño, Gabriel Bsteh, Antonio Belenguer-Benavides, Jose E Martínez-Rodríguez, Eduardo Agüera-Morales, Luisa M. Villar, Inmaculada Toboso, Florian Deisenhammer, Cristina Ramo, Patricia Urbaneja, Laura Navarro, Pedro Oliva, Inés González, J.A. García-Merino, Bonaventura Casanova, Ludwig Rasche, Albert Saiz, Agustín Oterino, Antonio Uccelli, Daniela Galimberti, J.C. Álvarez-Cermeño, Manuel Comabella, Carmen Espejo, Jette L. Frederiksen, Harald Hegen, J.M. Prieto, José M. García-Domínguez, Francisco Padilla, Luis I Casanova, Xavier Montalban, Carmen Calles, Lamberto Landete, Diego Franciotta, Ester Quintana, Patricia Mulero, Elio Scarpini, Rafael Arroyo, Roberto Alvarez-Lafuente, Fernando Romero, Yolanda Aladro, Amalia Tejeda-Velarde, Alfonso Muriel, Lucienne Costa Frossard, Lluís Ramió-Torrentà, María Otano, Yolanda Blanco, Carlos López de Silanes, Dolores Paramo, Elena Álvarez, Ana B Caminero, Pablo Eguía

Publikováno v: Frontiers in Neurology
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
Toboso, I, Tejeda-Velarde, A, Alvarez-Lafuente, R, Arroyo, R, Hegen, H, Deisenhammer, F, Sainz de la Maza, S, Alvarez-Cermeño, J C, Izquierdo, G, Paramo, D, Oliva, P, Casanova, B, Agüera-Morales, E, Franciotta, D, Gastaldi, M, Fernández, O, Urbaneja, P, Garcia-Dominguez, J M, Romero, F, Laroni, A, Uccelli, A, Perez-Sempere, A, Saiz, A, Blanco, Y, Galimberti, D, Scarpini, E, Espejo, C, Montalban, X, Rasche, L, Paul, F, González, I, Álvarez, E, Ramo, C, Caminero, A B, Aladro, Y, Calles, C, Eguía, P, Belenguer-Benavides, A, Ramió-Torrentà, L, Quintana, E, Martínez-Rodríguez, J E, Oterino, A, López de Silanes, C, Casanova, L I, Landete, L, Frederiksen, J, Bsteh, G, Mulero, P, Comabella, M, Hernández, M A, Espiño, M, Prieto, J M, Pérez, D, Otano, M, Padilla, F, García-Merino, J A, Navarro, L, Muriel, A, Frossard, L C & Villar, L M 2020, ' New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab ', Frontiers in Neurology, vol. 11, 579438 . https://doi.org/10.3389/fneur.2020.579438
Frontiers in Neurology, Vol 11 (2020)
Frontiers in neurology
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

Overview: We assessed the role of age and disease activity as new factors contributing to establish the risk of progressive multifocal leucoencephalopathy in multiple sclerosis patients treated with natalizumab in 36 University Hospitals in Europe. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef36835f42e2ef0f7c67c0021ce9224e
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=8697

Antibody-Dependent NK Cell Activation Differentially Targets EBV-Infected Cells in Lytic Cycle and Bystander B Lymphocytes Bound to Viral Antigen–Containing Particles

Autor: Jordi Sintes, Miguel López-Botet, Jose E Martínez-Rodríguez, Aura Muntasell, Elisenda Alari-Pahissa, María López-Montañés

Publikováno v: The Journal of Immunology. 199:656-665

NK cells have been reported to respond against EBV-infected B cells in the lytic cycle and to control the viral infection involving IFN-γ secretion. Early reports proposed a role for NK cell Ab-dependent cellular cytotoxicity (ADCC) triggered via Fc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78be1bbbe13eb655ca8cdf8cc47e66b
https://doi.org/10.4049/jimmunol.1601574

Multi-centre validation of a flow cytometry method to identify optimal responders to interferon-beta in multiple sclerosis

Autor: Guadalupe Herrera, Elisenda Alari-Pahissa, Alexandru Vlagea, David San Segundo, Juana Gil-Herrera, María Gema Salgado, J. M. Ferrer, Silvia Presas-Rodríguez, Cecilia Muñoz-Calleja, Juan Pablo Cuello, Patricia Urbaneja, Carmen Cámara, Herena Eixarch, Luisa M. Villar, Breogán Rodríguez-Acevedo, Rocío Hernández-Clares, Luis Querol, Eugenia Martinez-Hernandez, Virginia Meca-Lallana, Francisco Gascón-Gimenez, Tamara Castillo-Triviño, María Jesús Pinto-Medel, Jose E Martínez-Rodríguez, Margarita Massot, Agustín Oterino, Aina Teniente-Serra, Alfonso Muriel, Ernesto Roldán, Larraitz Aragón, Montserrat Gómez-Gutiérrez, Esther Moga, Eulalia Rodríguez-Martín, Noelia Villarrubia, Alvaro Prada

Publikováno v: CLINICA CHIMICA ACTA
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Clinica Chimica Acta
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA

Background and objectives: Percentages of blood CD19 + CD5 + B cells and CD8 + perforin + T lymphocytes can predict response to Interferon (IFN)-beta treatment in relapsing-remitting multiple sclerosis (RRMS) patients. We aimed to standardize their d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df68d100788243bef2c87c45c5567e7c
https://pubmed.ncbi.nlm.nih.gov/30408481

Factors associated with early outcome in patients with large-vessel carotid strokes

Autor: Jose E Martínez-Rodríguez, Angel Ois, Jordi Jimenez-Conde, Elisa Cuadrado-Godia, Ana Rodríguez-Campello, Jaume Roquer, Sara Jimena, Jaume Capellades, Eva Giralt-Steinhauer, Carol Soriano-Tarraga

Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 84:305-309

To describe the severity and early neurological deterioration (END) in patients with symptomatic carotid stenosis and to analyse the influence of related factors.Observational cohort study of patients with ischaemic stroke, ipsilateral carotid stenos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656e480e5f4e4eba9d9c19ff87d5e241
https://doi.org/10.1136/jnnp-2012-303638

Natural killer receptors distribution in multiple sclerosis: Relation to clinical course and interferon-beta therapy

Autor: Jose E Martínez-Rodríguez, Andrea Sáez-Borderías, Elvira Munteis, Jaume Roquer, Neus Romo, Miguel López-Botet

Publikováno v: Clinical Immunology. 137:41-50

NK cell receptors (NKR) are expressed in subsets of NK and CD8+ T cells, lymphocytes involved in multiple sclerosis (MS) pathogenesis. Clinical implications of NKR expression in MS are unknown. Here, we show that the proportions of CD8+ T cells displ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9282b1a91cc85c7761ee572df8e5dc02
https://doi.org/10.1016/j.clim.2010.06.002