Human adipose tissue as a major reservoir of cytomegalovirus-reactive T cells

Autor: Anaïs Redruello-Romero, Maria S. Benitez-Cantos, David Lopez-Perez, Jesús García-Rubio, Francisco Tamayo, Daniel Pérez-Bartivas, Sara Moreno-SanJuan, Isabel Ruiz-Palmero, Jose D. Puentes-Pardo, Jose R. Vilchez, Miguel Á. López-Nevot, Federico García, Carlos Cano, Josefa León, Ángel Carazo

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionCytomegalovirus (CMV) is a common herpesvirus with a high prevalence worldwide. After the acute infection phase, CMV can remain latent in several tissues. CD8 T cells in the lungs and salivary glands mainly control its reactivation contro

Externí odkaz: https://doaj.org/article/4147881549024d33b528b39269ad4e4e

In Patients With Obesity, the Number of Adipose Tissue Mast Cells Is Significantly Lower in Subjects With Type 2 Diabetes

Autor: David Lopez-Perez, Anaïs Redruello-Romero, Jesús Garcia-Rubio, Carlos Arana, Luis A. Garcia-Escudero, Francisco Tamayo, Jose D. Puentes-Pardo, Sara Moreno-SanJuan, Javier Salmeron, Armando Blanco, Julio Galvez, Josefa Leon, Ángel Carazo

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Type 2 diabetes (T2D) is a rising global health problem mainly caused by obesity and a sedentary lifestyle. In healthy individuals, white adipose tissue (WAT) has a relevant homeostatic role in glucose metabolism, energy storage, and endocrine signal

Externí odkaz: https://doaj.org/article/8213980e590e43e2ba2c4b49b47d88f1

Core Circadian Clock Proteins as Biomarkers of Progression in Colorectal Cancer

Autor: María I. Aroca-Siendones, Sara Moreno-SanJuan, Jose D. Puentes-Pardo, Michela Verbeni, Javier Arnedo, Julia Escudero-Feliu, María García-Costela, Adelina García-Robles, Ángel Carazo, Josefa León

Publikováno v: Biomedicines, Vol 9, Iss 8, p 967 (2021)

Colorectal cancer (CRC) is one of the most common tumours in developed countries. Although its incidence and mortality rates have decreased, its prognosis has not changed, and a high percentage of patients with CRC develop relapse (metachronous metas

Externí odkaz: https://doaj.org/article/9e5d61434c8b49debfcdf859c78cd7bf

Narrow leafed Lupin (Lupinus angustifolius L.) β-Conglutin seed proteins as a new natural cytotoxic agents against breast cancer cells

Autor: Julia Escudero-Feliu, María García-Costela, Sara Moreno-SanJuan, Jose D. Puentes-Pardo, Sandra Ríos Arrabal, Paula González-Novoa, María Isabel Núñez, Ángel Carazo, Jose C. Jimenez-Lopez, Josefa León

Publikováno v: Nutrients
Volume 15
Issue 3
Pages: 523

Breast cancer (BC) is the most widespread tumor in women and the second type of most common cancer worldwide. Despite all the technical and medical advances in existing therapies, between 30 and 50% of patients with BC will develop metastasis, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebf5859cad94fd8d669169514de4edd
http://hdl.handle.net/10261/309004

Endothelin-1 as a Mediator of Heme Oxygenase-1-Induced Stemness in Colorectal Cancer: Influence of p53

Autor: Sandra Ríos-Arrabal, Ángel Carazo, Julia Escudero-Feliu, Michela Verbeni, Josefa León, Sara Moreno-SanJuan, Alicia Martín-Lagos Maldonado, Jorge Casado, Ágata Szuba, Carlos Cano, Jose D. Puentes-Pardo, Cristina González-Puga, María García-Costela

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Journal of Personalized Medicine, Vol 11, Iss 509, p 509 (2021)
Journal of Personalized Medicine
Volume 11
Issue 6
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)

Heme oxygenase-1 (HO-1) is an antioxidant protein implicated in tumor progression, metastasis, and resistance to therapy. Elevated HO-1 expression is associated with stemness in several types of cancer, although this aspect has not yet been studied i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cc87282144686498aa3ffa1fe47cf4
http://hdl.handle.net/10481/69009