Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jose D, Murga"'
Autor:
Glen A Coburn, Danielle N Fisch, Sameer M Moorji, Jean-Marc de Muys, Jose D Murga, Dorothy Paul, Kathleen P Provoncha, Yakov Rotshteyn, Amy Q Han, Dapeng Qian, Paul J Maddon, William C Olson
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35351 (2012)
Combinations of direct-acting anti-virals offer the potential to improve the efficacy, tolerability and duration of the current treatment regimen for hepatitis C virus (HCV) infection. Viral entry represents a distinct therapeutic target that has bee
Externí odkaz:
https://doaj.org/article/a9586f6cd3614cdea54f6f4f8141f1da
Autor:
William C. Olson, Wells W. Magargal, Vincent A. DiPippo, Sameer M. Moorji, Jose D. Murga, Amy Han
Publikováno v:
The Prostate. 75:242-254
BACKGROUND Antibody–drug conjugates (ADCs) are an emerging class of cancer therapies that have demonstrated favorable activity both as single agents and as components of combination regimens. Phase 2 testing of an ADC targeting prostate-specific me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59a486e6e3047751b27cbf559bf2b407
https://doi.org/10.1002/pros.22910
https://doi.org/10.1002/pros.22910
Autor:
Paul J. Maddon, Suzanne M. Pemrick, Jeffrey M. Jacobson, Marti Michael, Alton B. Kremer, Michael S. Saag, Melanie A. Thompson, Ralph Liporace, Robert Buice, Paul D'Ambrosio, Hieu Ly, Robert R. Redfield, William C. Olson, Mahesh C. Patel, Stephen A. Morris, Yakov Rotshteyn, Barry S. Zingman, Jose D. Murga, Hans Kroger, Joseph Joseph J Stavola, Carl J. Fichtenbaum, Margaret A. Fischl, Richard C. Reichman
Publikováno v:
The Journal of Infectious Diseases. 198:1345-1352
Background The current goal of human immunodeficiency virus type 1 (HIV-1) therapy is to maximally suppress viral replication. Securing this goal requires new drugs and treatment classes. The chemokine receptor CCR5 provides an entry portal for HIV-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747c451b72e8501332e838f138a0dba5
https://doi.org/10.1086/592169
https://doi.org/10.1086/592169
Autor:
Jose D, Murga, Sameer M, Moorji, Amy Q, Han, Wells W, Magargal, Vincent A, DiPippo, William C, Olson
Publikováno v:
The Prostate. 75(3)
Antibody-drug conjugates (ADCs) are an emerging class of cancer therapies that have demonstrated favorable activity both as single agents and as components of combination regimens. Phase 2 testing of an ADC targeting prostate-specific membrane antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66076553fbbac50f1fbee872a02c5b07
https://pubmed.ncbi.nlm.nih.gov/25327687
https://pubmed.ncbi.nlm.nih.gov/25327687
Autor:
Jose D. Murga, Kathleen Provoncha, Yakov Rotshteyn, Sameer M. Moorji, William C. Olson, D. Paul, Jean-Marc de Muys, Amy Han, Danielle N. Fisch, Dapeng Qian, Paul J. Maddon, Glen A. Coburn
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35351 (2012)
PLoS ONE
PLoS ONE
Combinations of direct-acting anti-virals offer the potential to improve the efficacy, tolerability and duration of the current treatment regimen for hepatitis C virus (HCV) infection. Viral entry represents a distinct therapeutic target that has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1ce627cbf9f4a54b49d87810732f13
http://europepmc.org/articles/PMC3335862?pdf=render
http://europepmc.org/articles/PMC3335862?pdf=render
Publikováno v:
Cancer Research. 74:798-798
Introduction: Androgen receptor (AR), the PI3K/mTOR signaling pathway and prostate-specific membrane antigen (PSMA) represent significant potential targets for prostate cancer therapy. The present study examined the cross-regulation and co-targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55770f19c16977b1b42aceb6d70117ee
https://doi.org/10.1158/1538-7445.am2014-798
https://doi.org/10.1158/1538-7445.am2014-798
Autor:
Yakov Rotshteyn, M. Canfield, C. Gauss, S. Mohamed, Paul J. Maddon, Dapeng Qian, Kathleen Provoncha, Danielle N. Fisch, William C. Olson, Sameer M. Moorji, Glen A. Coburn, J.-M. de Muys, D. Paul, Amy Han, Jose D. Murga
Publikováno v:
Journal of Hepatology. 50:S5-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3373b62974cd57c105d993e3bfb50229
https://doi.org/10.1016/s0168-8278(09)60009-x
https://doi.org/10.1016/s0168-8278(09)60009-x
Publikováno v:
Molecular Cancer Therapeutics. 12:A262-A262
Introduction: Recent approvals of new prostate cancer (PCa) drugs and a growing number of pipeline agents have created opportunities for designing rational drug combinations. Potent antiandrogens such as enzalutamide and abiraterone affect expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::203da78e97364e45b901a852080a148d
https://doi.org/10.1158/1535-7163.targ-13-a262
https://doi.org/10.1158/1535-7163.targ-13-a262
Publikováno v:
Journal of Clinical Oncology. 31:e16007-e16007
e16007 Background: Recent approvals of four new prostate cancer (PCa) drugs and a growing number of pipeline agents have created opportunities for designing rational drug combinations. Potent antiandrogens such as enzalutamide and abiraterone affect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::242a44340ea35be6c14327fadb445327
https://doi.org/10.1200/jco.2013.31.15_suppl.e16007
https://doi.org/10.1200/jco.2013.31.15_suppl.e16007
Autor:
Jose D. Murga, Jean-Marc de Muys, Alexandra K. Bernardino, Yakov Rotshteyn, Mark G. Hamilton, Heidi Fraser, D. Paul, Amy Han, Dapeng Qian
Publikováno v:
Cancer Research. 71:4492-4492
Background: The simultaneous dysregulation of both PI3K and Ras-MAPK pathways is characteristic of some of the most aggressive forms of human cancer (e.g. tumors with Ras mutations). It has been demonstrated in preclinical studies that effective trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c40b7b3fb317fd0128e0c8383adda2a
https://doi.org/10.1158/1538-7445.am2011-4492
https://doi.org/10.1158/1538-7445.am2011-4492