Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jose Carlos Quilles Junior"'
Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells
Autor:
Jose Carlos Quilles Junior, Andrei Leitão, Fernanda dos Reis Rocho Carlos, Tracey D. Bradshaw, Viviane W. Mignone, Lyudmila Turyanska, A. Montanari, Maria Augusta Arruda
Publikováno v:
RSC Advances. 9:36699-36706
Cysteine proteases play a key role in tumorigenesis causing protein degradation and promoting invasive tumour growth. Cathepsin L is overexpressed in cancer cells and could provide a specific target for delivery of anticancer agents. We encapsulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61228f33402913582d11843a051e2ade
https://doi.org/10.1039/c9ra07161j
https://doi.org/10.1039/c9ra07161j
Autor:
Carlos A. Montanari, Cristiana Gonçalez, Mark Furber, Juliana C. Gomes, Jose Carlos Quilles Junior, Andrei Leitão, Antonio C. B. Burtoloso, Sérgio de Albuquerque, Peter W. Kenny, Jean F. R. Ribeiro, Josmar R. Rocha
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005343 (2017)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
The cysteine protease cruzipain is considered to be a validated target for therapeutic intervention in the treatment of Chagas disease. Anti-trypanosomal activity against the CL Brener strain of T. cruzi was observed in the 0.1 μM to 1 μM range for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1280c65d1b7c5d096885ca5d538c5e
https://doi.org/10.1371/journal.pntd.0005343
https://doi.org/10.1371/journal.pntd.0005343