Neurodegeneration Is Associated to Changes in Serum Insulin-like Growth Factors

Autor: Svetlana Busiguina, Ana M. Fernandez, Vicente Barrios, Ruth Clark, Daniel L. Tolbert, Jose Berciano, Ignacio Torres-Aleman

Publikováno v: Neurobiology of Disease, Vol 7, Iss 6, Pp 657-665 (2000)

Serum levels of insulin and insulin-like growth factors and their binding proteins (IGFs and IGFBPs, respectively) are changed in human neurodegenerative diseases of very different etiology, such as Alzheimer's disease, amyotrophic lateral sclerosis,

Externí odkaz: https://doaj.org/article/099c97e329284b43b1ab52443877e911

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

Autor: Healy, Daniel G., Mario, Falchi, O'Sullivan, Sean S., Bonifati, Vincenzo, Alexandra, Durr, Susan, Bressman, Alexis, Brice, Jan, Aasly, Zabetian, Cyrus P., Stefano, Goldwurm, Ferreira, Joaquim J., Eduardo, Tolosa, Kay, Denise M., Christine, Klein, Williams, David R., Connie, Marras, Lang, Anthony E., Wszolek, Zbigniew K., Jose, Berciano, Schapira, Anthony H. V., Timothy, Lynch, Bhatia, Kailash P., Thomas, Gasser, Lees, Andrew J., Wood, Nicholas W., International Lrrk Consortium, Collaborators, Tazir, M., Ysmail Dahlouk, F., Belarbi, S., Hecham, N., Barbosa, E., Chien, H. F., Rieder, C. R., Jardim, L. B., Rogaeva, E., Lesage, S., Lohmann, E., Vidailhet, M., Bonnet, A. M., Agid, Y., Pollak, P., Tison, F., Durif, F., Broussolle, E., Berg, D., Hagenah, J., Gosal, D., Gibson, M., Vanacore, Nicola, Berardelli, Alfredo, Fabbrini, Giovanni, Fabrizio, E., Meco, Giuseppe, Stocchi, F., Dalla Libera, A., De Mari, M., Lamberti, P., Cossu, G., Pezzoli, G., Zini, M., Tesei, S., Zecchinelli, A., Sironi, F., Antonini, A., Mariani, C., Sacilotto, G., Meucci, N., Canesi, M., Di Fonzo, A., Oostra, B., Correia Guedes, L., Rosa, Mm, Coelho, M., Sampaio, C., Gaig, C., C. S., Lu, Wu Chou, Y. H., Quinn, N. P., Abou Sleiman, P. M., Muqit, M. M., Khan, N. L., Gandhi, S., Vaughan, J., Payami, H., Nutt, J. J., Factor, S. A., Higgins, D. S., Farrer, M. J., Hulihan, M., Brown, L., Mata, I. F., Samii, A., Yearout, D., Griffith, A., Leis, B. C., Roberts, J. W.

Publikováno v: Lancet Neurology, 7(7), 583-590. Lancet Publishing Group
The Lancet Neurology
The Lancet Neurology, 2008, 7 (7), pp.583-590
The Lancet Neurology, Elsevier, 2008, 7 (7), pp.583-590

Summary Background Mutations in LRRK2 , the gene that encodes leucine-rich repeat kinase 2, are a cause of Parkinson's disease (PD). The International LRRK2 Consortium was established to answer three key clinical questions: can LRRK2 -associated PD b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cd088b2dcd94204ede5ac47e6f14f6

Presentation, diagnosis, and management of multiple system atrophy in Europe: final analysis of the European multiple system atrophy registry

Autor: Martin, Köllensperger, Felix, Geser, Jean-Pierre, Ndayisaba, Sylvia, Boesch, Klaus, Seppi, Karen, Ostergaard, Erik, Dupont, A, Cardozo, Eduardo, Tolosa, Michael, Abele, Thomas, Klockgether, Farid, Yekhlef, Francois, Tison, Christine, Daniels, Günther, Deuschl, Miguel, Coelho, Cristina, Sampaio, Maria, Bozi, Niall, Quinn, Anette, Schrag, Chris J, Mathias, Clare, Fowler, Christer F, Nilsson, Håkan, Widner, Nicole, Schimke, Wolfgang, Oertel, Francesca, Del Sorbo, Alberto, Albanese, Maria Teresa, Pellecchia, Paolo, Barone, Ruth, Djaldetti, Carlo, Colosimo, Giuseppe, Meco, Antonio, Gonzalez-Mandly, Jose, Berciano, Tanya, Gurevich, Nir, Giladi, Monique, Galitzky, Olivier, Rascol, Christoph, Kamm, Thomas, Gasser, Uwe, Siebert, Werner, Poewe, Gregor K, Wenning

Publikováno v: Köllensperger, M, Geser, F, Ndayisaba, J-P, Boesch, S, Seppi, K, Østergaard, K, Dupont, E, Cardozo, A, Tolosa, E, Abele, M, Klockgether, T, Yekhlef, F, Tison, F, Daniels, C, Deuschl, G, Coelho, M, Sampaio, C, Bozi, M, Quinn, N, Schrag, A, Mathias, C J, Fowler, C, Nilsson, C F, Widner, H, Schimke, N, Oertel, W, Del Sorbo, F, Albanese, A, Pellecchia, M T, Barone, P, Djaldetti, R, Colosimo, C, Meco, G, Gonzalez-Mandly, A, Berciano, J, Gurevich, T, Giladi, N, Galitzky, M, Rascol, O, Kamm, C, Gasser, T, Siebert, U, Poewe, W, Wenning, G K & EMSA-SG 2010, ' Presentation, diagnosis, and management of multiple system atrophy in Europe: final analysis of the European multiple system atrophy registry ', Movement Disorders, vol. 25, no. 15, pp. 2604-12 . https://doi.org/10.1002/mds.23192

Multiple system atrophy (MSA) is a Parkinson's Disease (PD)-like α-synucleinopathy clinically characterized by dysautonomia, parkinsonism, cerebellar ataxia, and pyramidal signs in any combination. We aimed to determine whether the clinical presenta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e3b13489c415150d92fa0168063fb714
https://pure.au.dk/portal/da/publications/presentation-diagnosis-and-management-of-multiple-system-atrophy-in-europe-final-analysis-of-the-european-multiple-system-atrophy-registry(484fe90e-63c0-44a1-a3b0-9966e4a0db1e).html

A functional polymorphism regulating dopamine β‐hydroxylase influences against Parkinson's disease.

Autor: Daniel G. Healy, Patrick M. Abou‐Sleiman, Tetsutaro Ozawa, Andrew J. Lees, Kailash Bhatia, Kourosh R. Ahmadi, Ullrich Wullner, Jose Berciano, J. Carsten Moller, Christoph Kamm, Katrin Burk, Paolo Barrone, Eduardo Tolosa, Niall Quinn, David B. Goldstein, Nicholas W. Wood

Publikováno v: Annals of Neurology; Mar2004, Vol. 55 Issue 3, p443-446, 4p

Serum and cerebrospinal fluid biomarker profiles in acute SARS-CoV-2-associated Guillain-Barré syndrome.

Autor: Berciano, José

Publikováno v: Brain Communications; 2021, Vol. 3 Issue 4, p1-2, 2p