Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Jose Baselga"'
Autor:
Sherene Loi, Stefan Michiels, Jose Baselga, John M S Bartlett, Sandeep K Singhal, Vicky S Sabine, Andrew H Sims, Tarek Sahmoud, J Michael Dixon, Martine J Piccart, Christos Sotiriou
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0216175 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0053292.].
Externí odkaz:
https://doaj.org/article/d71c1eb6584e47cfbf6051eab8cecf7c
Autor:
Natalia Martín-Martín, Marco Piva, Jelena Urosevic, Paula Aldaz, James D. Sutherland, Sonia Fernández-Ruiz, Leire Arreal, Verónica Torrano, Ana R. Cortazar, Evarist Planet, Marc Guiu, Nina Radosevic-Robin, Stephane Garcia, Iratxe Macías, Fernando Salvador, Giacomo Domenici, Oscar M. Rueda, Amaia Zabala-Letona, Amaia Arruabarrena-Aristorena, Patricia Zúñiga-García, Alfredo Caro-Maldonado, Lorea Valcárcel-Jiménez, Pilar Sánchez-Mosquera, Marta Varela-Rey, Maria Luz Martínez-Chantar, Juan Anguita, Yasir H. Ibrahim, Maurizio Scaltriti, Charles H. Lawrie, Ana M. Aransay, Juan L. Iovanna, Jose Baselga, Carlos Caldas, Rosa Barrio, Violeta Serra, Maria dM Vivanco, Ander Matheu, Roger R. Gomis, Arkaitz Carracedo
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Targeting PML in acute promyelocytic leukaemia has changed the outcome of patients with this disease. Here, the authors demonstrated that PML is also a potential therapeutic target in breast cancer where it specifically regulates cancer initiating ce
Externí odkaz:
https://doaj.org/article/e6f5403164b5464bb99d566e04f080ef
Autor:
Peter J O’Brien, Rajeev Ramanathan, Jonathan M Yingling, Jose Baselga, Mace L Rothenberg, et al
Publikováno v:
Biologics: Targets & Therapy, Vol 2008, Iss Issue 3, Pp 563-569 (2008)
Peter J O’Brien1, Rajeev Ramanathan2, Jonathan M Yingling1, Jose Baselga3, Mace L Rothenberg4, Michael Carducci5, Thomas Daly1, Dorothy Adcock2, Michael Lahn11Eli Lilly and Company Research Laboratories, Lilly Corporate Center, Indianapolis, IN, US
Externí odkaz:
https://doaj.org/article/eb6a465b749d4abc800f350f26a9a6fa
Autor:
Sherene Loi, Stefan Michiels, Jose Baselga, John M S Bartlett, Sandeep K Singhal, Vicky S Sabine, Andrew H Sims, Tarek Sahmoud, J Michael Dixon, Martine J Piccart, Christos Sotiriou
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53292 (2013)
The phosphatidylinositol 3' kinase (PI3K) pathway is commonly activated in breast cancer and aberrations such as PI3K mutations are common. Recent exciting clinical trial results in advanced estrogen receptor-positive (ER) breast cancer support mTOR
Externí odkaz:
https://doaj.org/article/6b52976f3af14e91b6fddd339081c482
Autor:
Mariona Graupera, Oriol Casanovas, Jose Baselga, Francesc Viñals, Maria Milà-Guasch, Ana Angulo-Urarte, Erika Monelli, Laura Martin, Pau Castel, Ana M. Figueiredo, Adriana Soler
Analysis of GDC-0941 effects on cell proliferation ; Supplemental Figure 2 Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703c4f9360ab5dce042d98a305280466
https://doi.org/10.1158/1078-0432.22466178
https://doi.org/10.1158/1078-0432.22466178
Autor:
Jose Baselga, Luc Dirix, Samit Hirawat, Cristian Massacesi, David W. Sternberg, Emmanuelle Di Tomaso, Joseph T. Beck, Ander Urruticoechea, Ana Bosch, Sophie Ruquet, David Mills, Stefan De Buck, Qinhua Ru, Shaun Su, Guy Jerusalem, Johanna Bendell, Cristina Saura
PDF file - 45K, Summary of adverse events suspected to be study-drug related by grade (safety set).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d4f8cc908d06b83f2aa2189bf400b8
https://doi.org/10.1158/1078-0432.22451552
https://doi.org/10.1158/1078-0432.22451552
Autor:
Josep Tabernero, Jose Baselga, Howard Fingert, José-Alejandro Pérez-Fidalgo, Laura Maños, Inma Blasco, Adelaida Piera, Juan Manuel Sanchis-Garcia, JungAh Jung, Jordi Andreu, Susana Roselló, Karthik Venkatakrishnan, Teresa Macarulla, Jeffrey Ecsedy, Desamparados Roda, Elena Elez, Andres Cervantes
Purpose: Aurora A kinase (AAK) is a key regulator of mitosis and a target for anticancer drug development. This phase I study investigated the safety, pharmacokinetics, and pharmacodynamics of MLN8237 (alisertib), an investigational, oral, selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a84836ab2c1904c39f1406746ede1d
https://doi.org/10.1158/1078-0432.c.6522377.v1
https://doi.org/10.1158/1078-0432.c.6522377.v1
Autor:
Michail Ignatiadis, Sarah-Jane Dawson, Christos Sotiriou, Sherene Loi, Martine Piccart, Jose Baselga, Jens Huober, Wolfgang Janni, Takayuki Ueno, Andrew Wardley, Stephen Chia, Daniela Rosa, Serena Di Cosimo, Vanessa Rodrik-Outmezguine, Debora Fumagalli, Marion Maetens, Evandro de Azambuja, Ghizlane Rouas, Ian Bradburry, Christine Campbell, David Venet, Maria Joao Silva, Françoise Rothé
Forest plots for the test of association between changes between baseline and week 2 in ctDNA detection, tested either by taking differences for continuous variables or by taking subgroups of patients who had detectable ctDNA at baseline or not, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3233ec9632142ac606d2707c892ec4a
https://doi.org/10.1158/1078-0432.22470251.v1
https://doi.org/10.1158/1078-0432.22470251.v1
Autor:
Michail Ignatiadis, Sarah-Jane Dawson, Christos Sotiriou, Sherene Loi, Martine Piccart, Jose Baselga, Jens Huober, Wolfgang Janni, Takayuki Ueno, Andrew Wardley, Stephen Chia, Daniela Rosa, Serena Di Cosimo, Vanessa Rodrik-Outmezguine, Debora Fumagalli, Marion Maetens, Evandro de Azambuja, Ghizlane Rouas, Ian Bradburry, Christine Campbell, David Venet, Maria Joao Silva, Françoise Rothé
Purpose:In the neoadjuvant treatment (NAT) setting, dual HER2-targeted therapy is associated with increased pathologic complete response (pCR) rates compared with each therapy alone. Biomarkers allowing to predict treatment response during NAT are ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdc64dda2eb2b284632c023023d7f04
https://doi.org/10.1158/1078-0432.c.6527480.v1
https://doi.org/10.1158/1078-0432.c.6527480.v1
Autor:
Gerald Edelman, Coumaran Egile, Yi Xu, Linh T. Nguyen, A. Douglas Laird, Christian Scheffold, Shuchi S. Pandya, Irene Braña, Jose Baselga, Eunice L. Kwak, Cynthia Bedell, Jordi Rodon, Geoffrey I. Shapiro
PDF file - 1641K, Effect of SAR245408 on plasma fasting insulin and glucose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b19731350a0d5e36474ba801261994e
https://doi.org/10.1158/1078-0432.22448138
https://doi.org/10.1158/1078-0432.22448138