Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jose Antonio Escario"'
Autor:
Alexandra Ibáñez-Escribano, Leyre Pernaute Lau, Juan José Nogal-Ruiz, Alicia Gómez-Barrio, Jose Antonio Escario, Michael A. Zeligs
Publikováno v:
Proceedings, Vol 1, Iss 6, p 645 (2017)
New, safe, well tolerated, and versatile anti-trichomonal agents for oral and topical use are needed to combat spreading resistance of Trichomonas vaginalis to metronidazole (MTZ). [...]
Externí odkaz:
https://doaj.org/article/5fa70984e779414299cc7d67a749b245
Publikováno v:
Proceedings, Vol 1, Iss 6, p 653 (2017)
Edelfosine (ET-18-OCH3) is an alkylphospholipid with an analogous structure to miltefosine. Both molecules are active against kinetoplastids (Leishmania spp., Trypanosoma cruzi and Trypanosoma brucei). [...]
Externí odkaz:
https://doaj.org/article/404489a2abf44b52b9437d8f1e0d04fe
Autor:
Celia Bolumburu, Vega Zamora, María Muñoz-Algarra, Maria Luisa de la Cruz Conty, José Antonio Escario, Alexandra Ibáñez-Escribano
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 620 (2024)
More than one million sexually transmitted infections (STIs) occur every day, and Trichomonas vaginalis is responsible for more than 156 million cases each year worldwide. Nevertheless, epidemiological studies of this parasite in Europe are scarce. T
Externí odkaz:
https://doaj.org/article/f0c16cfe5fe549d9822351e36eeeb0d9
Autor:
Alexandra Ibáñez-Escribano, Cristina Fonseca-Berzal, Mónica Martínez-Montiel, Manuel Álvarez-Márquez, María Gómez-Núñez, Manuel Lacueva-Arnedo, Teresa Espinosa-Buitrago, Tania Martín-Pérez, José Antonio Escario, Penélope Merino-Montiel, Sara Montiel-Smith, Alicia Gómez-Barrio, Óscar López, José G. Fernández-Bolaños
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 781-791 (2022)
Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evalu
Externí odkaz:
https://doaj.org/article/2e3a62e95f4841cdadefb7f108d1beea
Autor:
Jose Antonio Escario Garcia-Trevijano, Tania Ueda Nakamura, Juan José Nogal-Ruiz, Vicente J. Arán, Jean Henrique da Silva Rodrigues, Alicia Gómez-Barrio, Arlene Correa, Diego Sangi
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85706 (2014)
PLoS ONE
PLoS ONE
BackgroundChagas' disease is a condition caused by the protozoan Trypanosoma cruzi that affects millions of people, mainly in Latin America where it is considered endemic. The chemotherapy for Chagas disease remains a problem; the standard treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e418df448c9761395872c7e3895a0c
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24465654/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24465654/pdf/?tool=EBI
Autor:
Sergio Sifontes-Rodríguez, Lianet Monzote-Fidalgo, Nilo Castañedo-Cancio, Ana Margarita Montalvo-Álvarez, Yamilé López-Hernández, Niurka Mollineda Diogo, Juan Francisco Infante-Bourzac, Oliver Pérez-Martín, Alfredo Meneses-Marcel, José Antonio Escario García-Trevijano, Miguel Ángel Cabrera-Pérez
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 110, Iss 2, Pp 166-173 (2015)
Despite recent advances in the treatment of some forms of leishmaniasis, the available drugs are still far from ideal due to inefficacy, parasite resistance, toxicity and cost. The wide-spectrum antimicrobial activity of 2-nitrovinylfuran compounds h
Externí odkaz:
https://doaj.org/article/2ff87b6086bc49b2a1d74e21942ab074
Autor:
Alexandra Ibáñez Escribano, Alfredo Meneses Marcel, Yanetsy Machado Tugores, Juan José Nogal Ruiz, Vicente J Arán Redó, José Antonio Escario García-Trevijano, Alicia Gómez Barrio
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 107, Iss 5, Pp 637-643 (2012)
A fluorimetric microassay that uses a redox dye to determine the viability of the flagellate Trichomonas vaginalis has been optimised to provide a more sensitive method to evaluate potential trichomonacidal compounds. Resazurin has been used in recen
Externí odkaz:
https://doaj.org/article/3d54a80d7ae7461d8654683bf4d01c96
Autor:
Ana Le-Senne, Susana Muelas-Serrano, Carlos Fernández-Portillo, José Antonio Escario, Alicia Gómez-Barrio
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 97, Iss 8, Pp 1101-1105 (2002)
Clone CL B5 of Trypanosoma cruzi is a beta-galactosidase expressing organism that was genetically transfected to be used for in vitro pharmacological screening. Biological parameters were determined, evaluating growth kinetics of epimastigotes, metac
Externí odkaz:
https://doaj.org/article/caa3962b946545baa7f292ce71ad995d
Autor:
Susana Muelas, Margarita Suárez, Rolando Pérez, Hortensia Rodríguez, Carmen Ochoa, José Antonio Escario, Alicia Gómez-Barrio
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 97, Iss 2, Pp 269-272 (2002)
Cytotoxicity assays of 24 new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivatives were performed. The 17 compounds with higher anti-epimastigote activity and lower cytotoxicity were, thereafter, screened against amastigote of Trypan
Externí odkaz:
https://doaj.org/article/f2499a187a30463e940085fb729c6de0