Inside the Thrombus: Association of Hemostatic Parameters With Outcomes in Large Vessel Stroke Patients

Autor: Juan Marta-Enguita, Manuel Navarro-Oviedo, Roberto Muñoz, Jorge Olier-Arenas, Guillermo Zalba, Ramon Lecumberri, Maite Mendioroz, Jose A. Paramo, Carmen Roncal, Josune Orbe

Publikováno v: Frontiers in Neurology, Vol 12 (2021)

Background: Actual clinical management of ischemic stroke (IS) is based on restoring cerebral blood flow using tissue plasminogen activator (tPA) and/or endovascular treatment (EVT). Mechanical thrombectomy has permitted the analysis of thrombus stru

Externí odkaz: https://doaj.org/article/fc6107e98de44532bc7424ea8d954279

Lipocalin-2 and Calprotectin Potential Prognosis Biomarkers in Peripheral Arterial Disease

Autor: Goren Saenz-Pipaon, Susana Ravassa, Katrine L. Larsen, Esther Martinez-Aguilar, Josune Orbe, Jose A. Rodriguez, Leopoldo Fernandez-Alonso, Arantxa Gonzalez, Jose L. Martín-Ventura, Jose A. Paramo, Jes S. Lindholt, Carmen Roncal

Publikováno v: Saenz-Pipaon, G, Ravassa, S, Larsen, K L, Martinez-Aguilar, E, Orbe, J, Rodriguez, J A, Fernandez-Alonso, L, Gonzalez, A, Martín-Ventura, J L, Paramo, J A, Lindholt, J S & Roncal, C 2022, ' Lipocalin-2 and Calprotectin Potential Prognosis Biomarkers in Peripheral Arterial Disease ', European Journal of Vascular and Endovascular Surgery, vol. 63, no. 4, pp. 648-656 . https://doi.org/10.1016/j.ejvs.2022.01.012

Objective: Peripheral arterial disease (PAD) is the most prevalent cardiovascular (CV) condition globally. Despite the high CV risk of PAD patients, no reliable predictors of adverse clinical evolution are yet available. In this regard, previous tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6f2587b940ce5753d1fb72225fb9ab
https://pubmed.ncbi.nlm.nih.gov/35307155

High serum levels of tissue inhibitor of matrix metalloproteinase-1 during the first week of a malignant middle cerebral artery infarction in non-surviving patients

Autor: Leonardo Lorente, María M. Martín, Luis Ramos, Mónica Argueso, Juan J. Cáceres, Jordi Solé-Violán, Alejandro Jiménez, Juan M. Borreguero-León, Agustín F. González-Rivero, Josune Orbe, José A. Rodríguez, José A. Páramo

Publikováno v: BMC Neurology, Vol 19, Iss 1, Pp 1-7 (2019)

Abstract Background Higher circulating levels of tissue inhibitor of matrix metalloproteinases (TIMP)-1 early after ischemic stroke have been associated with lower survival. The objectives of this study were to determine serum TIMP-1 levels during th

Externí odkaz: https://doaj.org/article/52364d672bc94bef8c21be308c23d00c

Association of SDF1 and MMP12 with Atherosclerosis and Inflammation: Clinical and Experimental Study

Autor: María Marcos-Jubilar, Josune Orbe, Carmen Roncal, Florencio J. D. Machado, José Antonio Rodriguez, Alejandro Fernández-Montero, Inmaculada Colina, Raquel Rodil, Juan C. Pastrana, José A. Páramo

Publikováno v: Life, Vol 11, Iss 5, p 414 (2021)

BACKGROUND: Atherosclerosis is the main etiology of cardiovascular diseases (CVD), associated to systemic inflammation. Matrix metalloproteinases (MMPs) are related to atherosclerosis progression through the SDF1/CXCR4 axis promoting macrophages recr

Externí odkaz: https://doaj.org/article/97bc620222cb4a0db13540bdb9525b2d

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