Zobrazeno 1 - 10 of 37 pro vyhledávání: '"Jose A. Godoy-Lugo"'
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Akademický článek
Cardiac NF-κB Acetylation Increases While Nrf2-Related Gene Expression and Mitochondrial Activity Are Impaired during the Progression of Diabetes in UCD-T2DM Rats
Autor: Max A. Thorwald, Jose A. Godoy-Lugo, Ruben Rodriguez, Kimber L. Stanhope, James L. Graham, Peter J. Havel, Henry Jay Forman, Rudy M. Ortiz
Publikováno v: Antioxidants, Vol 11, Iss 5, p 927 (2022)
The onset of type II diabetes increases the heart’s susceptibility to oxidative damage because of the associated inflammation and diminished antioxidant response. Transcription factor NF-κB initiates inflammation while Nrf2 controls antioxidant de
Externí odkaz: https://doaj.org/article/254042f19c804f419614973098541e60
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2
Alzheimer’s Disease associations of ferritin and glutathione with oxidative damage and neuronal loss
Autor: Max A. Thorwald, Jose A. Godoy-Lugo, Justine Silva, Elizabeth Head, Peggy A. O’Day, Todd E. Morgan, Henry Jay Forman, Caleb E. Finch
Publikováno v: bioRxiv
The role of reactive iron in Alzheimer’s Disease (AD) has major gaps. Little is known of AD changes in iron transport, glutathione-mediated oxidative repair, and associations with ApoE alleles. Intravascular blood was minimized by washing minced po
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2526a2d61bcaa4795da67af826f14228
https://europepmc.org/articles/PMC10081222/
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3
Glucose Increases Hepatic Mitochondrial Antioxidant Enzyme Activities in Insulin Resistant Rats Following Chronic Angiotensin Receptor Blockade
Autor: Jose A. Godoy-Lugo, Max A. Thorwald, Dora A. Mendez, Ruben Rodriguez, Daisuke Nakano, Akira Nishiyama, Rudy M. Ortiz
Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10897
International journal of molecular sciences, vol 23, iss 18
Non-alcoholic fatty liver disease (NAFLD) affects up to 20% of the world’s population. Overactivation of the angiotensin receptor type 1 (AT1) contributes to metabolic dysfunction and increased oxidant production, which are associated with NAFLD an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc88d1a8bb5c41387da9c13c80d3b9c6
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4
Improved lipogenesis gene expression in liver is associated with elevated plasma angiotensin 1-7 after AT1 receptor blockade in insulin-resistant OLETF rats
Autor: Jose A. Godoy-Lugo, Dora A. Mendez, Ruben Rodriguez, Akira Nishiyama, Daisuke Nakano, Jose G. Soñanez-Organis, Rudy M. Ortiz
Increased angiotensin II (Ang II) signaling contributes to insulin resistance and liver steatosis. In addition to ameliorating hypertension, angiotensin receptor blockers (ARBs) improve lipid metabolism and hepatic steatosis, which are impaired with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d7d064641e29399e18d56262469b78
https://escholarship.org/uc/item/8gp4311q
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5
Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats
Autor: Akira Nishiyama, David Y. Hui, Rudy M. Ortiz, Max Thorwald, Jose A. Godoy-Lugo, José G. Soñanez-Organis, Daisuke Nakano
Publikováno v: Endocrine
Purpose Angiotensin receptor blockers (ARBs) can ameliorate metabolic syndrome (MetS)-associated dyslipidemia, hepatic steatosis, and glucose intolerance, suggesting that angiotensin receptor (AT1) over-activation contributes to impaired lipid and gl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f910dab8c6b856b838f18dcef692a811
https://doi.org/10.1007/s12020-021-02834-7
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6
Neurotoxicity of Diesel Exhaust Particles
Autor: Kristina Shkirkova, Krista Lamorie-Foote, Nathan Zhang, Andrew Li, Arnold Diaz, Qinghai Liu, Max A. Thorwald, Jose A. Godoy-Lugo, Brandon Ge, Carla D’Agostino, Zijiao Zhang, Wendy J. Mack, Constantinos Sioutas, Caleb E. Finch, William J. Mack, Hongqiao Zhang
Publikováno v: Journal of Alzheimer's disease : JAD. 89(4)
Background: Air pollution particulate matter (PM) is strongly associated with risks of accelerated cognitive decline, dementia and Alzheimer’s disease. Ambient PM batches have variable neurotoxicity by collection site and season, which limits repli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c104af2a178b9cf2a3536e14dfbfc4
https://pubmed.ncbi.nlm.nih.gov/36031897
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8
Chronic AT1 blockade improves hyperglycemia by decreasing adipocyte inflammation and decreasing hepatic PCK1 and G6PC1 expression in obese rats
Autor: Akira Nishiyama, David G. Parkes, Andrew Lee, Ruben Rodriguez, Rudy M. Ortiz, Jose A. Godoy-Lugo, José Pablo Vázquez-Medina, Hiroyuki Ohsaki, Daisuke Nakano, Bridget Martinez
Publikováno v: American journal of physiology. Endocrinology and metabolism, vol 321, iss 5
Am J Physiol Endocrinol Metab
Inappropriate activation of the renin-angiotensin system decreases glucose uptake in peripheral tissues. Chronic angiotensin receptor type 1 (AT(1)) blockade (ARB) increases glucose uptake in skeletal muscle and decreases the abundance of large adipo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e94ad606dedc02ff026cc70c198208
https://escholarship.org/uc/item/0zz451t8
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9
Blood Transcriptome Profiling Reveals Diet-Induced Changes in Metabolic Pathway Gene Expression
Autor: Rudy M. Ortiz, Jaapna Dhillon, Jose A. Godoy-Lugo
Publikováno v: Curr Dev Nutr
OBJECTIVES: This study explored the effects of diet-induced (almonds vs. crackers) changes on blood transcriptome profiles of young adults. METHODS: Young adults (age: 18–22 years) were randomly assigned to consume either almonds (2 oz./d, n = 13)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda06f142b3205c6e4c6cccaeac25b87
https://europepmc.org/articles/PMC8182017/
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10
Regulation of lactate dehydrogenase in response to WSSV infection in the shrimp Litopenaeus vannamei
Autor: Jose A. Godoy-Lugo, Jesús A. Rosas-Rodríguez, Rudy M. Ortiz, Silvia Gómez-Jiménez, Alma B. Peregrino-Uriarte, José G. Soñanez-Organis, Gloria Yepiz-Plascencia, Magally L.E. Hernández-Palomares, L.A. Gámez-Alejo, J.F. Muñoz-Valle
Publikováno v: Fish & Shellfish Immunology. 74:401-409
Lactate dehydrogenase (LDH) is key for anaerobic glycolysis. LDH is induced by the hypoxia inducible factor −1 (HIF-1). HIF-1 induces genes involved in glucose metabolism and regulates cellular oxygen homeostasis. HIF-1 is formed by a regulatory α
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b65aba5a2e166462012551bc03780e
https://doi.org/10.1016/j.fsi.2018.01.011
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