Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jose A. Caparrós-Martín"'
Autor:
Jose A. Caparrós-Martín, Montserrat Saladie, S. Patricia Agudelo-Romero, F. Jerry Reen, Robert S. Ware, Peter D. Sly, Stephen M. Stick, Fergal O’Gara, on behalf of the COMBAT study group
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Background Cystic Fibrosis (CF) is a genetic condition characterized by neutrophilic inflammation and recurrent infection of the airways. How these processes are initiated and perpetuated in CF remains largely unknown. We have demonstrated a
Externí odkaz:
https://doaj.org/article/f172504a9a14488dad4153716e4e7c63
Autor:
Jose A. Caparrós-Martín, Patrice Maher, Natalie C. Ward, Montserrat Saladié, Patricia Agudelo-Romero, Stephen M. Stick, Dick C. Chan, Gerald F. Watts, Fergal O’Gara
Publikováno v:
Microorganisms, Vol 12, Iss 1, p 170 (2024)
Background. Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of global mortality, often associated with high blood levels of LDL cholesterol (LDL-c). Medications like statins and PCSK9 inhibitors, are used to manage LDL-c levels and
Externí odkaz:
https://doaj.org/article/cba51428b3f844d6ad21a21e02f0623e
Autor:
Adilah F. Ahmad, Jose A. Caparrós-Martín, Silvia Lee, Fergal O’Gara, Bu B. Yeap, Daniel J. Green, Mohammed Ballal, Natalie C. Ward, Girish Dwivedi
Publikováno v:
Microorganisms, Vol 11, Iss 5, p 1126 (2023)
The gut microbiome plays a significant role in regulating the host’s ability to store fat, which impacts the development of obesity. This observational cohort study recruited obese adult men and women scheduled to undergo sleeve gastrectomy and fol
Externí odkaz:
https://doaj.org/article/9ab846d6046a4cc0b7b6154357a7ce92
Systems Biology and Bile Acid Signalling in Microbiome-Host Interactions in the Cystic Fibrosis Lung
Autor:
David F. Woods, Stephanie Flynn, Jose A. Caparrós-Martín, Stephen M. Stick, F. Jerry Reen, Fergal O’Gara
Publikováno v:
Antibiotics, Vol 10, Iss 7, p 766 (2021)
The study of the respiratory microbiota has revealed that the lungs of healthy and diseased individuals harbour distinct microbial communities. Imbalances in these communities can contribute to the pathogenesis of lung disease. How these imbalances o
Externí odkaz:
https://doaj.org/article/4bc7955c5d1f41f59a050f47a828178e
Autor:
Jose A. Caparrós-Martín, Ricky R. Lareu, Joshua P. Ramsay, Jörg Peplies, F. Jerry Reen, Henrietta A. Headlam, Natalie C. Ward, Kevin D. Croft, Philip Newsholme, Jeffery D. Hughes, Fergal O’Gara
Publikováno v:
Microbiome, Vol 5, Iss 1, Pp 1-15 (2017)
Abstract Background Statins are a class of therapeutics used to regulate serum cholesterol and reduce the risk of heart disease. Although statins are highly effective in removing cholesterol from the blood, their consumption has been linked to potent
Externí odkaz:
https://doaj.org/article/fcc779b332e645babe743ff404a25475
Autor:
Stephanie Flynn, F. Jerry Reen, Jose A. Caparrós-Martín, David F. Woods, Jörg Peplies, Sarath C. Ranganathan, Stephen M. Stick, Fergal O'Gara
Publikováno v:
Microorganisms, Vol 8, Iss 11, p 1741 (2020)
Cystic fibrosis (CF) is a congenital disorder resulting in a multisystemic impairment in ion homeostasis. The subsequent alteration of electrochemical gradients severely compromises the function of the airway epithelia. These functional changes are a
Externí odkaz:
https://doaj.org/article/536164bcd4f144959b5ddee9439ea505
Autor:
Jose A. Caparrós-Martín, Stephanie Flynn, F. Jerry Reen, David F. Woods, Patricia Agudelo-Romero, Sarath C. Ranganathan, Stephen M. Stick, Fergal O’Gara
Publikováno v:
Diagnostics, Vol 10, Iss 5, p 282 (2020)
Background: Cystic fibrosis (CF) is a hereditary disorder in which persistent unresolved inflammation and recurrent airway infections play major roles in the initiation and progression of the disease. Little is known about triggering factors modulati
Externí odkaz:
https://doaj.org/article/97684a8e108f4820ad6cb7664001ff27
Autor:
Elizabeth Kicic-Starcevich, David G. Hancock, Thomas Iosifidis, Patricia Agudelo-Romero, Jose A. Caparros-Martin, Yuliya V. Karpievitch, Desiree Silva, Lidija Turkovic, Peter N. Le Souef, Anthony Bosco, David J. Martino, Anthony Kicic, Susan L. Prescott, Stephen M. Stick
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
IntroductionRecurrent wheezing disorders including asthma are complex and heterogeneous diseases that affect up to 30% of all children, contributing to a major burden on children, their families, and global healthcare systems. It is now recognized th
Externí odkaz:
https://doaj.org/article/63c7867954a64ed681c2a2469b6882d0
Autor:
Montserrat Saladié, Jose Antonio Caparrós-Martín, Patricia Agudelo-Romero, Peter A. B. Wark, Stephen M. Stick, Fergal O’Gara
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology, Vol 11 (2020)
In recent years the study of the commensal microbiota is driving a remarkable paradigm shift in our understanding of human physiology. However, intrinsic technical difficulties associated with investigating the Microbiomics of some body niches are ha
Autor:
Talya Conradie, Jose A. Caparros-Martin, Siobhon Egan, Anthony Kicic, Sulev Koks, Stephen M. Stick, Patricia Agudelo-Romero
Publikováno v:
Viruses, Vol 16, Iss 6, p 953 (2024)
Background: Respiratory viruses significantly impact global morbidity and mortality, causing more disease in humans than any other infectious agent. Beyond pathogens, various viruses and bacteria colonize the respiratory tract without causing disease
Externí odkaz:
https://doaj.org/article/cd92e2ad91b54ac1b2da298bdd492052