Výsledky vyhledávání - "Jose A Pérez-Simón"

Akademický článek

An Active Isodicentric X Chromosome in a Case of Refractory Anaemia with Ring Sideroblasts Associated with Marked Thrombocytosis

Autor: Rosario M. Morales Camacho, Javier Sanchez, Irene Marcos Luque, Ricardo Bernal, Jose F Falantes, Jose A Pérez-Simón

Publikováno v: Case Reports in Genetics, Vol 2014 (2014)

Refractory anaemia with ring sideroblasts and marked thrombocytosis (RARS-T) is a provisional entity in the World Health Organization (WHO) classification. It displays features characteristic of both myelodysplastic syndrome and myeloproliferative ne

Externí odkaz: https://doaj.org/article/ef367eeb794440209ce5ba07f03e7417

Zobrazit plný text záznamu

Akademický článek

ECP versus ruxolitinib in steroid-refractory acute GVHD – a retrospective study by the EBMT transplant complications working party

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionExtracorporal Photophoresis (ECP) is in clinical use for steroid-refractory and steroid-dependent acute GVHD (SR-aGVHD). Based on recent Phase-III study results, ruxolitinib has become the new standard of care for SR-aGVHD. Our aim was to

Externí odkaz: https://doaj.org/article/c87c15a038f44831ac8aefe6cd59a145

Zobrazit plný text záznamu

Akademický článek

LAG3 genotype of the donor and clinical outcome after allogeneic transplantation from HLA-identical sibling donors

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionThe association of polymorphisms in molecules involved in the immune response (checkpoint inhibitors) with the clinical outcome after allogeneic transplantation (alloHSCT) has been described. Lymphocyte Activation 3 (LAG3) is a surface pr

Externí odkaz: https://doaj.org/article/edd64b6599aa4fae83967b5ff39bce1c

Zobrazit plný text záznamu

Akademický článek

Current Status of CAR-T Cell Therapy in Multiple Myeloma

Autor: Juan Luis Reguera-Ortega, Estefanía García-Guerrero, Jose Antonio Pérez-Simón

Publikováno v: Hemato, Vol 2, Iss 4, Pp 660-671 (2021)

Current data on CAR-T cell-based therapy is really promising in multiple myeloma, especially in terms of response. In heavily pretreated patients, who have already received proteasome inhibitors, immunomodulatory drugs and monoclonal antibodies, curr

Externí odkaz: https://doaj.org/article/d265ed9f333140bd87ceb70041da0f8b

Zobrazit plný text záznamu

Akademický článek

All-trans retinoic acid works synergistically with the γ-secretase inhibitor crenigacestat to augment BCMA on multiple myeloma and the efficacy of BCMA-CAR T cells

Autor: Estefanía García-Guerrero, Luis G. Rodríguez-Lobato, Belén Sierro-Martínez, Sophia Danhof, Stephan Bates, Silke Frenz, Larissa Haertle, Ralph Götz, Markus Sauer, Leo Rasche, K. Martin Kortüm, Jose A. Pérez-Simón, Hermann Einsele, Michael Hudecek, Sabrina R. Prommersberger

Publikováno v: Haematologica, Vol 108, Iss 2 (2022)

B-cell maturation antigen (BCMA) is the lead antigen for chimeric antigen receptor (CAR) T-cell therapy in multiple myeloma (MM). A challenge is inter- and intra-patient heterogeneity in BCMA expression on MM cells and BCMA downmodulation under thera

Externí odkaz: https://doaj.org/article/c5afb352d346406386ae305b8e18e44f

Zobrazit plný text záznamu

SF3B1, RUNX1 and TP53 Mutations Significantly Impact the Outcome of Patients With Lower-Risk Myelodysplastic Syndrome

Autor: Jose F, Falantes, Francisco J, Márquez-Malaver, Estrella, Carrillo, Marta García, Culebras, Rosario, Morales, Concepción, Prats, Maria T, Vargas, Teresa, Caballero, Eduardo, Rodríguez-Arbolí, Ildefonso, Espigado, Jose Antonio, Pérez-Simón

Publikováno v: Clinical Lymphoma Myeloma and Leukemia. 22:e1059-e1066

[Introduction] Prognosis of patients with myelodysplastic syndrome (MDS), particularly the group with lower-risk disease (LR-MDS) is very heterogeneous. Several studies have described the prognostic value of recurrent somatic mutations in MDS includi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f61141dd9143ca59e143b4f79ad090
https://doi.org/10.1016/j.clml.2022.08.012

Zobrazit plný text záznamu

Akademický článek

Selection of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients Through the Identification of T-Cells Capable to Establish Stable Interactions With the Leukemic Cells: 'Doublet Technology'

Autor: Estefanía García-Guerrero, Luís I. Sánchez-Abarca, Esther Domingo, Teresa L. Ramos, Jose A. Bejarano-García, Jose A. Gonzalez-Campos, Teresa Caballero-Velázquez, Jose A. Pérez-Simón

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

The relevance of the immune system in cancer has long been studied. Autologous adoptive T cell therapies, based on the use of tumor infiltrating lymphocytes (TILs), have made great progress in recent years for the treatment of solid tumors, especiall

Externí odkaz: https://doaj.org/article/b30349e6feb14b70af54c005f9f65a5b

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání