Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Jose A Lopez-Escamez"'
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background DNA methylation may have a regulatory role in monogenic sensorineural hearing loss and complex, polygenic phenotypic forms of hearing loss, including age-related hearing impairment or Meniere disease. The purpose of this systemati
Externí odkaz:
https://doaj.org/article/a2e95e13bc774570be9fe9eea72e51ac
Autor:
Alberto Bernal-Robledano, Patricia Perez-Carpena, Dimitris Kikidis, Birgit Mazurek, Stefan Schoisswohl, Susanne Staudinger, Berthold Langguth, Winfried Schlee, Jose Antonio Lopez-Escamez
Publikováno v:
Clinical and Experimental Otorhinolaryngology, Vol 17, Iss 1, Pp 15-25 (2024)
Objectives. The study aimed to assess the relationship of tinnitus with hyperacusis with cognitive impairment as indicated by the Montreal Cognitive Assessment (MoCA) tool. Methods. This multicenter cross-sectional study included individuals with chr
Externí odkaz:
https://doaj.org/article/36012c08632a46a0ba9b7a15cacf461b
Autor:
Sonia Cabrera, Elena Sanchez, Teresa Requena, Manuel Martinez-Bueno, Jesus Benitez, Nicolas Perez, Gabriel Trinidad, Andrés Soto-Varela, Sofía Santos-Perez, Eduardo Martin-Sanz, Jesus Fraile, Paz Perez, Marta E Alarcon-Riquelme, Angel Batuecas, Juan M Espinosa-Sanchez, Ismael Aran, Jose A Lopez-Escamez
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112171 (2014)
Meniere's disease is an episodic vestibular syndrome associated with sensorineural hearing loss (SNHL) and tinnitus. Patients with MD have an elevated prevalence of several autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, anky
Externí odkaz:
https://doaj.org/article/c0deab1d2b6749dfb82b25ca3f116888
Autor:
Irene Gazquez, Andres Soto-Varela, Ismael Aran, Sofia Santos, Angel Batuecas, Gabriel Trinidad, Herminio Perez-Garrigues, Carlos Gonzalez-Oller, Lourdes Acosta, Jose A Lopez-Escamez
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26759 (2011)
BackgroundAutoimmunity appears to be associated with the pathophysiology of Meniere's disease (MD), an inner ear disorder characterized by episodes of vertigo associated with hearing loss and tinnitus. However, the prevalence of autoimmune diseases (
Externí odkaz:
https://doaj.org/article/b06a9a6ea68a4d56878deba16445c308
Using coding and non-coding rare variants to target candidate genes in patients with severe tinnitus
Autor:
Alvaro Gallego-Martinez, Alba Escalera-Balsera, Natalia Trpchevska, Paula Robles-Bolivar, Pablo Roman-Naranjo, Lidia Frejo, Patricia Perez-Carpena, Jan Bulla, Silvano Gallus, Barbara Canlon, Christopher R. Cederroth, Jose A. Lopez-Escamez
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Tinnitus is the phantom percept of an internal non-verbal set of noises and tones. It is reported by 15% of the population and it is usually associated with hearing and/or brain disorders. The role of structural variants (SVs) in coding and
Externí odkaz:
https://doaj.org/article/5734f936892f451682d332dfb3663313
Autor:
Alba Escalera-Balsera, Alberto M. Parra-Perez, Alvaro Gallego-Martinez, Lidia Frejo, Juan Martin-Lagos, Victoria Rivero de Jesus, Paz Pérez-Vázquez, Patricia Perez-Carpena, Jose A. Lopez-Escamez
Publikováno v:
Genes, Vol 15, Iss 1, p 22 (2023)
Meniere disease (MD) is a debilitating disorder of the inner ear defined by sensorineural hearing loss (SNHL) associated with episodes of vertigo and tinnitus. Severe tinnitus, which occurs in around 1% of patients, is a multiallelic disorder associa
Externí odkaz:
https://doaj.org/article/d3a2e11eb5724298af3389a6a3140093
Autor:
Pablo Roman‐Naranjo, Alberto M. Parra‐Perez, Alba Escalera‐Balsera, Andres Soto‐Varela, Alvaro Gallego‐Martinez, Ismael Aran, Nicolas Perez‐Fernandez, David Bächinger, Andreas H. Eckhard, Rocio Gonzalez‐Aguado, Lidia Frejo, Jose A. Lopez‐Escamez
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 6, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/ed8231449a64420dac355f364908ecbf
Autor:
Angelo Augusto M. Sumalde, Melissa A. Scholes, Olivia A. Kalmanson, Elizabeth A. Terhune, Lidia Frejo, Cambria I. Wethey, Pablo Roman-Naranjo, Patrick M. Carry, Samuel P. Gubbels, Jose A. Lopez-Escamez, Nancy Hadley-Miller, Regie Lyn P. Santos-Cortez
Publikováno v:
Genes, Vol 14, Iss 4, p 831 (2023)
Vertigo due to vestibular dysfunction is rare in children. The elucidation of its etiology will improve clinical management and the quality of life of patients. Genes for vestibular dysfunction were previously identified in patients with both hearing
Externí odkaz:
https://doaj.org/article/ecde0cae61534709b4a6d72867c6f590
Publikováno v:
Cells, Vol 12, Iss 7, p 988 (2023)
Genetic sensorineural hearing loss and Meniere disease have been associated with rare variations in the coding and non-coding region of the human genome. Most of these variants were classified as likely pathogenic or variants of unknown significance
Externí odkaz:
https://doaj.org/article/406ab6065fa14a9bab31e553d8571217
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 15, p 4597 (2022)
Tinnitus disorder is a bothersome perception of a composite noise or tone in the ears in the absence of an external source, associated with emotional distress, cognitive dysfunction, and/or autonomic arousal [...]
Externí odkaz:
https://doaj.org/article/33746f7364644d2d89ccb20ac8e41f3e