Long-term exposure to combination antiretroviral therapy and risk of death from specific causes: no evidence for any previously unidentified increased risk due to antiretroviral therapy

Autor: Kowalska, Justyna D., Joanne Reekie, Amanda Mocroft, Peter Reiss, Bruno Ledergerber, Jose Gatell, Arminio Monforte, Antonella D., Andrew Phillips, Lundgren, Jens D., Ole Kirk, EuroSIDA Study Group, Matti Ristola

Publikováno v: AIDS (London, England), 26(3), 315-323. Lippincott Williams and Wilkins
University of Helsinki
AIDS; Vol 26
Kowalska, J D, Reekie, J, Mocroft, A, Reiss, P, Ledergerber, B, Gatell, J, d'Arminio Monforte, A, Phillips, A, Lundgren, J, Kirk, O, EuroSIDA Study Group & Pedersen, C 2012, ' Long-term exposure to combination antiretroviral therapy and risk of death from specific causes : no evidence for any previously unidentified increased risk due to antiretroviral therapy ', AIDS, vol. 26, no. 3, pp. 315-23 . https://doi.org/10.1097/QAD.0b013e32834e8805

Background: Despite the known substantial benefits of combination antiretroviral therapy (cART), cumulative adverse effects could still limit the overall long-term treatment benefit. Therefore we investigated changes in the rate of death with increas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49a41d3200898174608d8ce8225d805
http://hdl.handle.net/11573/610248

Risk of AIDS and death at given HIV-RNA and CD4 cell count, in relation to specific antiretroviral drugs in the regimen

Autor: Christian Holkmann, Olsen, Jose, Gatell, Bruno, Ledergerber, Christine, Katlama, Nina, Friis-Møller, Jonathan, Weber, Andrzéj, Horban, Schlomo, Staszewski, Jens D, Lundgren, Andrew N, Phillips

Publikováno v: AIDS (London, England). 19(3)

It is unknown whether the relationship between the HIV-RNA/CD4 cell count and risk of clinical disease continues to hold true for newer antiretroviral drugs approved without data from clinical endpoint trials.: To determine and compare whether rate r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4d583646a7a98be8676cbdc282c4826b
https://pubmed.ncbi.nlm.nih.gov/15718843

Determination of the Underlying Cause of Death in Three Multicenter International HIV Clinical Trials.

Autor: Alan Lifson, Waldo Belloso, Cate Carey, Richard Davey, Daniel Duprez, Wafaa El-Sadr, Jose Gatell, Daniela Gey, Jennifer Hoy, Eric Krum, Ray Nelson, Daniel Nixon, Nick Paton, Court Pedersen, George Perez, Richard Price, Ronald Prineas, Frank Rhame, James Sampson, John Worley

Publikováno v: HIV Clinical Trials; Vol. 9 Issue 3, p177-185, 9p

The clinical benefits of antiretroviral therapy in severely immunocompromised HIV-1-infected patients with and without complete viral suppression

Autor: Amanda Mocroft, Bannister, Wendy P., Ole Kirk, Kowalska, Justyna D., Peter Reiss, Arminio-Monforte, Antonella D., Jose Gatell, Martin Fisher, Hanna Trocha, Aza Rakhmanova, Lundgren, Jens D., The EuroSIDA Study in EuroCOORD, Matti Ristola

Publikováno v: University of Helsinki
Antiviral therapy, 17(7), 1291-1300. International Medical Press Ltd
Antiviral Therapy; Vol 17

Background The aim of this study was to determine whether there is a protective effect of combination anti-retroviral therapy (cART) on the development of clinical events in patients with ongoing severe immunosuppression. Methods A total of 3,780 pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497e3c87a66e6864596cbc79904590c7
https://researchportal.helsinki.fi/en/publications/5dbfab7c-e1a3-4990-a53d-db6aff3db516