Zobrazeno 1 - 10
of 41
pro vyhledávání: '"José-Rodrigo Rodríguez"'
Publikováno v:
Frontiers in Neuroanatomy, Vol 12 (2018)
Semithin sections are commonly used to examine large areas of tissue with an optical microscope, in order to locate and trim the regions that will later be studied with the electron microscope. Ideally, the observation of semithin sections would be f
Externí odkaz:
https://doaj.org/article/440047d535714426ad850a83d1570b3e
In response to different stress signals, the c-Jun NH2-terminal kinase (JNK) can trigger cell death. However, JNK also facilitates the survival and cell cycle progression of tumor cells by mechanisms that are poorly defined. Here, we show that schwan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f5cb301be999c1d02b6139681491b6
https://doi.org/10.1158/1541-7786.c.6542665.v1
https://doi.org/10.1158/1541-7786.c.6542665.v1
Supplementary Figures S1-S6 from Mitochondrial c-Jun NH2-Terminal Kinase Prevents the Accumulation of Reactive Oxygen Species and Reduces Necrotic Damage in Neural Tumor Cells that Lack Trophic Support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccf37e05f6a32af4da057bdc41f8129
https://doi.org/10.1158/1541-7786.22520521.v1
https://doi.org/10.1158/1541-7786.22520521.v1
Autor:
Marta Turegano-Lopez, Felix de las Pozas, Andrea Santuy, Jose-Rodrigo Rodriguez, Javier DeFelipe, Angel Merchan-Perez
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract The highly complex structure of the brain requires an approach that can unravel its connectivity. Using volume electron microscopy and a dedicated software we can trace and measure all nerve fibers present within different samples of brain t
Externí odkaz:
https://doaj.org/article/2d3fe19929d54a1db8f07bea9f42451f
Autor:
José-Rodrigo Rodríguez, Angel Merchán-Pérez, Juncal González-Soriano, Javier DeFelipe, Lidia Alonso-Nanclares, Marta Turégano-López
Publikováno v:
Neuromethods ISBN: 9781071615218
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f1ec2a31067e956736f9a5889d3928
https://doi.org/10.1007/978-1-0716-1522-5_20
https://doi.org/10.1007/978-1-0716-1522-5_20
Autor:
Andrea Santuy, Fei Zhu, Seth G. N. Grant, Zhen Qiu, José-Rodrigo Rodríguez, Laura Tomás-Roca, Angel Merchán-Pérez, Javier DeFelipe, Juncal González-Soriano
Publikováno v:
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Santuy, A, Tomás-Roca, L, Rodríguez, J-R, González-Soriano, J, Zhu, F, Qiu, Z, Grant, S G N, DeFelipe, J & Merchan-Perez, A 2020, ' Estimation of the number of synapses in the hippocampus and brain-wide by volume electron microscopy and genetic labeling ', Scientific Reports, vol. 10, no. 1 . https://doi.org/10.1038/s41598-020-70859-5
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Santuy, A, Tomás-Roca, L, Rodríguez, J-R, González-Soriano, J, Zhu, F, Qiu, Z, Grant, S G N, DeFelipe, J & Merchan-Perez, A 2020, ' Estimation of the number of synapses in the hippocampus and brain-wide by volume electron microscopy and genetic labeling ', Scientific Reports, vol. 10, no. 1 . https://doi.org/10.1038/s41598-020-70859-5
Determining the number of synapses that are present in different brain regions is crucial to understand brain connectivity as a whole. Membrane-associated guanylate kinases (MAGUKs) are a family of scaffolding proteins that are expressed in excitator
Autor:
Marta Turégano-López, Andrea Santuy, José-Rodrigo Rodríguez, Lidia Alonso-Nanclares, Angel Merchán-Pérez, Javier DeFelipe
Publikováno v:
Cerebral Cortex (New York, NY)
Cerebral Cortex
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cerebral Cortex
Digital.CSIC. Repositorio Institucional del CSIC
instname
Mitochondria play a key role in energy production and calcium buffering, among many other functions. They provide most of the energy required by neurons, and they are transported along axons and dendrites to the regions of higher energy demands. We h
Publikováno v:
Brain Structure & Function, ISSN 1863-2653, 2018-01, Vol. 223, No. 1
Archivo Digital UPM
Universidad Politécnica de Madrid
Brain Structure & Function
Archivo Digital UPM
Universidad Politécnica de Madrid
Brain Structure & Function
Knowing the proportions of asymmetric (excitatory) and symmetric (inhibitory) synapses in the neuropil is critical for understanding the design of cortical circuits. We used focused ion beam milling and scanning electron microscopy (FIB/SEM) to obtai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e373fc9e0280b4adb6b2514fddc881f
http://oa.upm.es/54648/
http://oa.upm.es/54648/
Autor:
José-Rodrigo Rodríguez, Alberto Ferrús, Sergio Casas-Tintó, Tilman Triphan, Alfonso Martín-Peña, Roland Strauss, Valerie Chevalier, Angel Acebes
Publikováno v:
European Journal of Neuroscience. 39:1586-1601
Cellular ultrastructures for signal integration are unknown in any nervous system. The ellipsoid body (EB) of the Drosophila brain is thought to control locomotion upon integration of various modalities of sensory signals with the animal internal sta
Autor:
Santiago González, José-Rodrigo Rodríguez, Víctor Robles, Pedro Larrañaga, Javier DeFelipe, Concha Bielza, Angel Merchán-Pérez
Publikováno v:
Cerebral Cortex (New York, NY)
Cerebral Cortex, ISSN 1047-3211, 2014, Vol. 24, No. 6
Archivo Digital UPM
Universidad Politécnica de Madrid
Cerebral Cortex, ISSN 1047-3211, 2014, Vol. 24, No. 6
Archivo Digital UPM
Universidad Politécnica de Madrid
In the cerebral cortex, most synapses are found in the neuropil, but relatively little is known about their 3-dimensional organization. Using an automated dual-beam electron microscope that combines focused ion beam milling and scanning electron micr