Bile Cast Nephropathy: A Pathologic Finding with Manifold Causes Displayed in an Adult with Alcoholic Steatohepatitis and in a Child with Wilson’s Disease

Autor: Jose Torrealba, Nathan T. Sweed, Daniel Burguete, Allen R. Hendricks

Publikováno v: Case Reports in Nephrology and Dialysis, Vol 8, Iss 3, Pp 207-215 (2018)

Bile cast nephropathy (BCN) is seen in patients who have acute kidney injury and severe hyperbilirubinemia due to a wide range of hepatobiliary system diseases. Findings seen by renal biopsy include acute tubular injury with necrotic and sloughed epi

Externí odkaz: https://doaj.org/article/7308c811819b4b37a1a293eec9601837

Data from An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors

Autor: James Brugarolas, Somasekar Seshagiri, Steffen Durinck, Zora Modrusan, Eric Stawiski, Jingxuan He, Wenbin Guo, Xin Luo, Jose Torrealba, Alexander Filatenkov, Mingyi Chen, Zhiqun Xie, Christina Stevens, Oreoluwa Onabolu, Danni Luo, Xinlei Wang, Min S. Kim, Allison Joyce, Tiffani McKenzie, Yi-Feng Gu, Qurratulain Yousuf, Leonard D. Goldstein, He Zhang, Jason J. Luke, Ivan Pedrosa, Ze Zhang, Raquibul Hannan, Bijay S. Jaiswal, Payal Kapur, Rong Lu, Tao Wang

By leveraging tumorgraft (patient-derived xenograft) RNA-sequencing data, we developed an empirical approach, DisHet, to dissect the tumor microenvironment (eTME). We found that 65% of previously defined immune signature genes are not abundantly expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b18ebe78bf41d90220e8e435388a2
https://doi.org/10.1158/2159-8290.c.6546844

Supplementary File from An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors

Autor: James Brugarolas, Somasekar Seshagiri, Steffen Durinck, Zora Modrusan, Eric Stawiski, Jingxuan He, Wenbin Guo, Xin Luo, Jose Torrealba, Alexander Filatenkov, Mingyi Chen, Zhiqun Xie, Christina Stevens, Oreoluwa Onabolu, Danni Luo, Xinlei Wang, Min S. Kim, Allison Joyce, Tiffani McKenzie, Yi-Feng Gu, Qurratulain Yousuf, Leonard D. Goldstein, He Zhang, Jason J. Luke, Ivan Pedrosa, Ze Zhang, Raquibul Hannan, Bijay S. Jaiswal, Payal Kapur, Rong Lu, Tao Wang

The full technical details of DisHet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2e0a2d9909382bbf1aa83d172164ad
https://doi.org/10.1158/2159-8290.22532824.v1

Supplementary Table 3 from An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors

Autor: James Brugarolas, Somasekar Seshagiri, Steffen Durinck, Zora Modrusan, Eric Stawiski, Jingxuan He, Wenbin Guo, Xin Luo, Jose Torrealba, Alexander Filatenkov, Mingyi Chen, Zhiqun Xie, Christina Stevens, Oreoluwa Onabolu, Danni Luo, Xinlei Wang, Min S. Kim, Allison Joyce, Tiffani McKenzie, Yi-Feng Gu, Qurratulain Yousuf, Leonard D. Goldstein, He Zhang, Jason J. Luke, Ivan Pedrosa, Ze Zhang, Raquibul Hannan, Bijay S. Jaiswal, Payal Kapur, Rong Lu, Tao Wang

Gene ontology analysis shows enriched GO terms of the 904 eTME genes (20x cutoff) (first sheet), the 778 and the 610 eTME genes (20x cutoff) that are not captured by the Immunome alone and Immunome+ESTIMATE+Winslow gene signatures (second and third s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa48808ba34476d63c1a55fc31d147e
https://doi.org/10.1158/2159-8290.22532815

Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular-pathologic correlation

Autor: Rajasree Menon, Andrew S. Bomback, Blue B. Lake, Christy Stutzke, Stephanie M. Grewenow, Steven Menez, Vivette D. D’Agati, Sanjay Jain, Richard Knight, Stewart H. Lecker, Isaac Stillman, Steve Bogen, Laurence H. Beck, Sushrut Waikar, Gearoid M. McMahon, Astrid Weins, Mia R. Colona, Nir Hacohen, Paul J. Hoover, Mark Aulisio, William S. Bush, Dana C. Crawford, John O'toole, Emilio Poggio, John Sedor, Leslie Cooperman, Stacey Jolly, Leal Herlitz, Jane Nguyen, Agustin Gonzalez-Vicente, Ellen Palmer, Dianna Sendrey, Carissa Vinovskis, Petter M. Bjornstad, Paul Appelbaum, Jonathan M. Barasch, Vivette D. D'Agati, Krzysztof Kiryluk, Karla Mehl, Pietro A. Canetta, Ning Shang, Olivia Balderes, Satoru Kudose, Shweta Bansal, Theodore Alexandrov, Helmut Rennke, Tarek M. El-Achkar, Yinghua Cheng, Pierre C. Dagher, Michael T. Eadon, Kenneth W. Dunn, Katherine J. Kelly, Timothy A. Sutton, Daria Barwinska, Michael J. Ferkowicz, Seth Winfree, Sharon Bledsoe, Marcelino Rivera, James C. Williams, Ricardo Melo Ferreira, Chirag R. Parikh, Celia P. Corona-Villalobos, Avi Rosenberg, Sylvia E. Rosas, Neil Roy, Mark Williams, Evren U. Azeloglu, Cijang He, Ravi Iyengar, Jens Hansen, Yuguang Xiong, Brad Rovin, Samir Parikh, John P. Shapiro, Christopher R. Anderton, Ljiljana Pasa-Tolic, Dusan Velickovic, Jessica Lukowski, George Oliver, Joseph Ardayfio, Jack Bebiak, Keith Brown, Catherine E. Campbell, John Saul, Anna Shpigel, Robert Koewler, Taneisha Campbell, Lynda Hayashi, Nichole Jefferson, Glenda V. Roberts, Roy Pinkeney, Olga Troyanskaya, Rachel Sealfon, Katherine R. Tuttle, Yury Goltsev, Kun Zhang, Zoltan G. Laszik, Garry Nolan, Patrick Boada, Minnie Sarwal, Tara Sigdel, Paul J. Lee, Rita R. Alloway, E. Steve Woodle, Heather Ascani, Ulysses G.J. Balis, Jeffrey B. Hodgin, Matthias Kretzler, Chrysta Lienczewski, Laura H. Mariani, Becky Steck, Yougqun He, Edgar Otto, Jennifer Schaub, Victoria M. Blanc, Sean Eddy, Ninive C. Conser, Jinghui Luo, Paul M. Palevsky, Matthew Rosengart, John A. Kellum, Daniel E. Hall, Parmjeet Randhawa, Mitchell Tublin, Raghavan Murugan, Michele M. Elder, James Winters, Charles E. Alpers, Kristina N. Blank, Jonas Carson, Ian H. De Boer, Ashveena L. Dighe, Jonathan Himmelfarb, Sean D. Mooney, Stuart Shankland, Kayleen Williams, Christopher Park, Frederick Dowd, Robyn L. McClelland, Stephen Daniel, Andrew N. Hoofnagle, Adam Wilcox, Kumar Sharma, Manjeri Venkatachalam, Guanshi Zhang, Annapurna Pamreddy, Hongping Ye, Richard Montellano, Robert D. Toto, Miguel Vazquez, Simon C. Lee, R. Tyler Miller, Orson W. Moe, Jose Torrealba, Nancy Wang, Asra Kermani, Kamalanathan Sambandam, Harold Park, S. Susan Hedayati, Christopher Y. Lu, Anitha Vijayan, Joseph P. Gaut, Dennis Moledina, Francis P. Wilson, Ugochukwu Ugwuowo, Tanima Arora

Publikováno v: Kidney Int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd51674caba4cf76b6db4f600991ecc1
https://doi.org/10.1016/j.kint.2022.03.011