Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jose' N Onuchic"'
Autor:
Ola Karmi, Sarah H Holt, Luhua Song, Sagi Tamir, Yuting Luo, Fang Bai, Ammar Adenwalla, Merav Darash-Yahana, Yang-Sung Sohn, Patricia A Jennings, Rajeev K Azad, Jose' N Onuchic, Faruck Morcos, Rachel Nechushtai, Ron Mittler
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175796 (2017)
The NEET proteins mitoNEET (mNT) and nutrient-deprivation autophagy factor-1 (NAF-1) are required for cancer cell proliferation and resistance to oxidative stress. NAF-1 and mNT are also implicated in a number of other human pathologies including dia
Externí odkaz:
https://doaj.org/article/b509885fae5a481cb87866730a617cd9
Autor:
Mohit Kumar Jolly, Marcelo Boareto, Mingyang Lu, Jose’ N Onuchic, Cecilia Clementi, Eshel Ben-Jacob
Publikováno v:
New Journal of Physics, Vol 17, Iss 5, p 055021 (2015)
Notch pathway is an evolutionarily conserved cell–cell communication mechanism governing cell-fate during development and tumor progression. It is activated when Notch receptor of one cell binds to either of its ligand—Delta or Jagged—of anothe
Externí odkaz:
https://doaj.org/article/0a3ffc0241644ff387e9dc9b3c797c0d
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 3, p e1005456 (2017)
One of the most important roles of cells is performing their cellular tasks properly for survival. Cells usually achieve robust functionality, for example, cell-fate decision-making and signal transduction, through multiple layers of regulation invol
Externí odkaz:
https://doaj.org/article/0360172bfda54553bbb0ac02de521949
Proteins are the workhorse of life. They are the building infrastructure of living systems; they are the most efficient molecular machines known, and their enzymatic activity is still unmatched in versatility by any artificial system. Perhaps protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973d69158a6050b6e25805486c5eeacb
https://zenodo.org/record/6778287
https://zenodo.org/record/6778287
Publikováno v:
F1000Research, Vol 5 (2016)
Experimentally derived structural constraints have been crucial to the implementation of computational models of biomolecular dynamics. For example, not only does crystallography provide essential starting points for molecular simulations but also hi
Externí odkaz:
https://doaj.org/article/9f03ac29b4f042c8a74f461946b0ab99
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious, and transmission involves a series of processes that may be targeted by vaccines and therapeutics. During transmission, host cell invasion is controlled by a large-sca
Autor:
Prakash Kulkarni, Vitor B. P. Leite, Susmita Roy, Supriyo Bhattacharyya, Atish Mohanty, Srisairam Achuthan, Divyoj Singh, Rajeswari Appadurai, Govindan Rangarajan, Keith Weninger, John Orban, Anand Srivastava, Mohit Kumar Jolly, Jose N. Onuchic, Vladimir N. Uversky, Ravi Salgia
Publikováno v:
Biophysics Reviews. 3:011306
Intrinsically disordered proteins (IDPs) are proteins that lack rigid 3D structure. Hence, they are often misconceived to present a challenge to Anfinsen's dogma. However, IDPs exist as ensembles that sample a quasi-continuum of rapidly interconverti
Publikováno v:
Biophysical Journal. 121:160a
Autor:
Alexander, Schug, Martin, Weigt, James A, Hoch, Jose N, Onuchic, Terence, Hwa, Hendrik, Szurmant
Publikováno v:
Methods in enzymology. 471
Two-component signal transduction systems enable cells in bacteria, fungi, and plants to react to extracellular stimuli. A sensor histidine kinase (SK) detects such stimuli with its sensor domains and transduces the input signals to a response regula
Autor:
Nancy S, Sung, Jeffrey I, Gordon, George D, Rose, Elizabeth D, Getzoff, Stephen J, Kron, David, Mumford, Jose N, Onuchic, Norbert F, Scherer, DeWitt L, Sumners, Nancy J, Kopell
Publikováno v:
Science (New York, N.Y.). 301(5639)