Upregulation of HOX genes promotes cell migration and proliferation in head and neck squamous cell carcinoma

Autor: Cibele Cardoso, Josane de Freitas Sousa, Felipe Freitas-Castro, Graziela de Moura Aguiar, Natália Volgarine Scaraboto, Sarah C. Simões, Anelisa Ramão, Jessica Rodrigues Plaça, Wilson A. Silva

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

BACKGROUND: Expression dysregulation of HOX homeobox genes has been observed in several cancers, including head and neck squamous cell carcinoma (HNSC). Although characterization of HOX gene roles in HNSC development has been reported, there is still

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a7a9aa2715e114a20efc73c02b17f8
https://pubmed.ncbi.nlm.nih.gov/34633333

Whole transcriptome analysis reveals correlation of long noncoding RNA ZEB1-AS1 with invasive profile in melanoma

Autor: I. I. Barros, Wilson A. Silva, Jessica Rodrigues Plaça, Enilza Maria Espreáfico, Carlos Alberto Oliveira de Biagi, Greice Andreotti de Molfetta, Luiza Ferreira de Araújo, Kamila Chagas Peronni, Ádamo Davi Diógenes Siena, Josane de Freitas Sousa

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports

Melanoma is the deadliest form of skin cancer, and little is known about the impact of deregulated expression of long noncoding RNAs (lncRNAs) in the progression of this cancer. In this study, we explored RNA-Seq data to search for lncRNAs associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0d12f7eb268344437ce0f4d59c9c76
http://link.springer.com/article/10.1038/s41598-019-47363-6

von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration

Autor: Kerstin Johnson, A.N. Aggouras, Josane de Freitas Sousa, Aline Cutrim Dragalzew, Michael Levin, Igor Schneider, Jessica L. Whited, Nicholas D. Leigh, Garrett S. Dunlap, Brian J. Haas, Duygu Payzin‐Dogru, S. Sessa

Publikováno v: Evolution & Development; (2020)
Evol Dev

Regenerative ability varies tremendously across species. A common feature of regeneration of appendages such as limbs, fins, antlers, and tails is the formation of a blastema--a transient structure that houses a pool of progenitor cells that regenera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f2c20a0cf07e751dd36024e88eadae
https://lup.lub.lu.se/record/8379571e-b21e-40c9-afec-523eed247dce

Figure S1. Statistics of the lungfish reference transcriptome and similarity among RNA-seq libraries.;Figure S2. Gene ontology enrichment analysis of genes upregulated in the lungfish 14 dpa tail blastema as compared to uninjured tail. ;Figure S3. In situ hybridization of sense-control probes for select genes upregulated in the 14 dpa lungfish tail blastema relative to uninjured tail tissue. from Salamander-like tail regeneration in the West African lungfish

Autor: Verissimo, Kellen Matos, Perez, Louise Neiva, Dragalzew, Aline Cutrim, Gayani Senevirathne, Darnet, Sylvain, Wainna Renata Barroso Mendes, Neves, Ciro Ariel Dos Santos, Santos, Erika Monteiro Dos, Moraes, Cassia Nazare De Sousa, Elewa, Ahmed, Shubin, Neil, Fröbisch, Nadia Belinda, Josane De Freitas Sousa, Schneider, Igor

(a) Statistics or the lungfish reference transcriptome. (b) BUSCO assessment of transcriptome completeness. (c) Principal component analysis (PCA) of uninjured and 14 dpa lungfish tail libraries. (d) Spearman correlation matrix of uninjured and 14 dp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115337f116353870a1333b44e87976bb

The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags

Autor: Helena, Brentani, Otávia L, Caballero, Anamaria A, Camargo, Aline M, da Silva, Wilson Araújo, da Silva, Emmanuel, Dias Neto, Marco, Grivet, Arthur, Gruber, Pedro Edson Moreira, Guimaraes, Winston, Hide, Christian, Iseli, C Victor, Jongeneel, Janet, Kelso, Maria Aparecida, Nagai, Elida Paula Benquique, Ojopi, Elisson C, Osorio, Eduardo M R, Reis, Gregory J, Riggins, Andrew John George, Simpson, Sandro, de Souza, Brian J, Stevenson, Robert L, Strausberg, Eloiza H, Tajara, Sergio, Verjovski-Almeida, Marcio Luis, Acencio, Mário Henrique, Bengtson, Fabiana, Bettoni, Walter F, Bodmer, Marcelo R S, Briones, Luiz Paulo, Camargo, Webster, Cavenee, Janete M, Cerutti, Luis Eduardo, Coelho Andrade, Paulo César, Costa dos Santos, Maria Cristina, Ramos Costa, Israel Tojal, da Silva, Marcos Roberto H, Estécio, Karine, Sa Ferreira, Frank B, Furnari, Milton, Faria, Pedro A F, Galante, Gustavo S, Guimaraes, Adriano Jesus, Holanda, Edna Teruko, Kimura, Maarten R, Leerkes, Xin, Lu, Rui M B, Maciel, Elizabeth A L, Martins, Katlin Brauer, Massirer, Analy S A, Melo, Carlos Alberto, Mestriner, Elisabete Cristina, Miracca, Leandro Lorenco, Miranda, Francisco G, Nobrega, Paulo S, Oliveira, Apua C M, Paquola, José Rodrigo C, Pandolfi, Maria Ines de Moura, Campos Pardini, Fabio, Passetti, John, Quackenbush, Beatriz, Schnabel, Mari Cleide, Sogayar, Jorge E, Souza, Sandro R, Valentini, Andre C, Zaiats, Elisabete Jorge, Amaral, Liliane A T, Arnaldi, Amelia Goes, de Araújo, Simone Aparecida, de Bessa, David C, Bicknell, Maria Eugenia, Ribeiro de Camaro, Dirce Maria, Carraro, Helaine, Carrer, Alex F, Carvalho, Christian, Colin, Fernando, Costa, Cyntia, Curcio, Ismael Dale Cotrim, Guerreiro da Silva, Neusa, Pereira da Silva, Márcia, Dellamano, Hamza, El-Dorry, Enilza Maria, Espreafico, Ari José, Scattone Ferreira, Cristiane, Ayres Ferreira, Maria Angela H Z, Fortes, Angelita Habr, Gama, Daniel, Giannella-Neto, Maria Lúcia C C, Giannella, Ricardo R, Giorgi, Gustavo Henrique, Goldman, Maria Helena S, Goldman, Christine, Hackel, Paulo Lee, Ho, Elza Myiuki, Kimura, Luiz Paulo, Kowalski, Jose E, Krieger, Luciana C C, Leite, Ademar, Lopes, Ana Mercedes S C, Luna, Alan, Mackay, Suely Kazue Nagahashi, Mari, Adriana Aparecida, Marques, Waleska K, Martins, André, Montagnini, Mario, Mourão Neto, Ana Lucia T O, Nascimento, A Munro, Neville, Marina P, Nobrega, Mike J, O'Hare, Audrey Yumi, Otsuka, Anna Izabel, Ruas de Melo, Maria Luisa, Paco-Larson, Gonçalo, Guimarães Pereira, Joao Bosco, Pesquero, Juliana Gilbert, Pessoa, Paula, Rahal, Claudia Aparecida, Rainho, Vanderlei, Rodrigues, Silvia Regina, Rogatto, Camila Malta, Romano, Janaina Gusmao, Romeiro, Benedito Mauro, Rossi, Monica, Rusticci, Renata, Guerra de Sá, Simone Cristina, Sant' Anna, Miriam L, Sarmazo, Teresa Cristina de Lima E, Silva, Fernando Augusto, Soares, Maria de Fátima, Sonati, Josane, de Freitas Sousa, Diana, Queiroz, Valéria, Valente, André Luiz, Vettore, Fabiola Elizabeth, Villanova, Marco Antonio, Zago, Heloisa, Zalcberg

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 100(23)

Whereas genome sequencing defines the genetic potential of an organism, transcript sequencing defines the utilization of this potential and links the genome with most areas of biology. To exploit the information within the human genome in the fight a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7e46ed91748cacbfe8d981929696a8
https://pubmed.ncbi.nlm.nih.gov/14593198