Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Josaih C Adaelu"'
Autor:
Bo Qi, Stanley Ng, Richard Chen, Martha L Healy-Fried, Josaih C Adaelu, Rajesh Ambat, Paul Balderes, Julia Lee, Troii Hall, Yun (Kenneth) Kang, Behnam Shanehsaz, William D Holmes, Dale L. Ludwig, Michael Barry, Matthew D Sauffer, Warren R. Emery, Amy Huebner
Publikováno v:
Pharmaceutical Bioprocessing. 3:477-487
6-Chloro- and 6-bromopurines can cross the blood-brain barrier and in situ give rise to substrates of multidrug resistance-associated proteins (MRPs). The electrophilic purines form glutathione conjugates in reactions catalyzed by intracellular gluta