Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Jos de Man"'
Autor:
Elisa Zanini, Nicole Forster-Gross, Felix Bachmann, Adrian Brüngger, Paul McSheehy, Karine Litherland, Karin Burger, Anna C. Groner, Mila Roceri, Luc Bury, Martin Stieger, Nicole Willemsen-Seegers, Jos de Man, Diep Vu-Pham, Helma W. E. van Riel, Guido J. R. Zaman, Rogier C. Buijsman, Laurenz Kellenberger, Heidi A. Lane
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundThreonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1) are common essential kinases that collaborate in activating the spindle assembly checkpoint (SAC) at the kinetochore, ensuring appropriate chromosome alignment and segregation pr
Externí odkaz:
https://doaj.org/article/cf9a84a3e06f4b3a99f2975a86de17db
Autor:
Horstmanshoff, H.F.J.
Publikováno v:
Gewina, Tijdschrift voor de geschiedenis der Geneeskunde, Natuurwetenschappen en Techniek, 15, 269-270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9008e5a706dced8f5e648e5443450c97
https://hdl.handle.net/1887/8863
https://hdl.handle.net/1887/8863
Autor:
Yvonne Grobben, Jos de Man, Antoon M. van Doornmalen, Michelle Muller, Nicole Willemsen-Seegers, Diep Vu-Pham, Winfried R. Mulder, Martine B. W. Prinsen, Joeri de Wit, Jan Gerard Sterrenburg, Freek van Cauter, Judith E. den Ouden, Anne M. van Altena, Leon F. Massuger, Joost C. M. Uitdehaag, Rogier C. Buijsman, Guido J. R. Zaman
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Indoleamine 2,3-dioxygenase (IDO1) is a key regulator of immune suppression by catalyzing the oxidation of L-tryptophan. IDO1 expression has been related to poor prognosis in several cancers and to resistance to checkpoint immunotherapies. We describ
Externí odkaz:
https://doaj.org/article/67d223be9e3a4daabf3fe18bdc0d30fd
Autor:
Yvonne Grobben, Joost C.M. Uitdehaag, Nicole Willemsen-Seegers, Werner W.A. Tabak, Jos de Man, Rogier C. Buijsman, Guido J.R. Zaman
Publikováno v:
Journal of Structural Biology: X, Vol 4, Iss , Pp 100014- (2020)
Arginase-1 is a manganese-dependent metalloenzyme that catalyzes the hydrolysis of L-arginine into L-ornithine and urea. Arginase-1 is abundantly expressed by tumor-infiltrating myeloid cells that promote tumor immunosuppression, which is relieved by
Externí odkaz:
https://doaj.org/article/69e071817d594ce39d3c3d4b2449e42f
Autor:
Joost C.M. Uitdehaag, Rogier C. Buijsman, Jos de Man, Martine B.W. Prinsen, Marion A.A. Libouban, Jeroen A.D.M. de Roos, Guido J.R. Zaman
Reanalyis of cell panel profilings of TTK inhibitors from literature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee9c9e0a9d15abcd6212654549af3cb
https://doi.org/10.1158/1535-7163.22507921.v1
https://doi.org/10.1158/1535-7163.22507921.v1
Autor:
Joost C.M. Uitdehaag, Rogier C. Buijsman, Jos de Man, Martine B.W. Prinsen, Marion A.A. Libouban, Jeroen A.D.M. de Roos, Guido J.R. Zaman
The spindle assembly checkpoint kinase TTK (Mps1) is a key regulator of chromosome segregation and is the subject of novel targeted therapy approaches by small-molecule inhibitors. Although the first TTK inhibitors have entered phase I dose escalatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45622369852106526e9379507da3c52a
https://doi.org/10.1158/1535-7163.c.6538819.v1
https://doi.org/10.1158/1535-7163.c.6538819.v1
Autor:
Guido J.R. Zaman, Rogier C. Buijsman, Jos de Man, Suzanne J.C. van Gerwen, Masaaki Sawa, Jeffrey Kooijman, Antoon M. van Doornmalen, Jelle Dylus, Judith R.F. de Vetter, Nicole Willemsen-Seegers, Martine B.W. Prinsen, Jeroen A.D.M. de Roos, Joost C.M. Uitdehaag
All IC50 values, reproducibility, other metrics, all correlations, ibrutinib biochemical IC50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83fe20e97c1e7c1a26b483c3f894380
https://doi.org/10.1158/1535-7163.22508719.v1
https://doi.org/10.1158/1535-7163.22508719.v1
Autor:
Guido J.R. Zaman, Rogier C. Buijsman, Suzanne J.C. van Gerwen, Jos de Man, Masaaki Sawa, Yusuke Kawase, Nicole Willemsen-Seegers, Jelle Dylus, Martine B.W. Prinsen, Jeroen A.D.M. de Roos, Jeffrey J. Kooijman, Joost C.M. Uitdehaag
Cell panel data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ec790414e94d2b2e88ac724d611ddf
https://doi.org/10.1158/1535-7163.22509141.v1
https://doi.org/10.1158/1535-7163.22509141.v1
Autor:
Guido J.R. Zaman, Rogier C. Buijsman, Suzanne J.C. van Gerwen, Jos de Man, Masaaki Sawa, Yusuke Kawase, Nicole Willemsen-Seegers, Jelle Dylus, Martine B.W. Prinsen, Jeroen A.D.M. de Roos, Jeffrey J. Kooijman, Joost C.M. Uitdehaag
Workflow for filtering cell line genomic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e663e953eb74c74f0846e43dea226e0
https://doi.org/10.1158/1535-7163.22509168.v1
https://doi.org/10.1158/1535-7163.22509168.v1
Autor:
Guido J.R. Zaman, Rogier C. Buijsman, Jos de Man, Suzanne J.C. van Gerwen, Masaaki Sawa, Jeffrey Kooijman, Antoon M. van Doornmalen, Jelle Dylus, Judith R.F. de Vetter, Nicole Willemsen-Seegers, Martine B.W. Prinsen, Jeroen A.D.M. de Roos, Joost C.M. Uitdehaag
Additional reproducibility data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003d19146fa08a6b23d7da87da7e39b2
https://doi.org/10.1158/1535-7163.22508731.v1
https://doi.org/10.1158/1535-7163.22508731.v1