Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Jos M. J. Lamers"'
Autor:
Folkert J. Ten Cate, Michelle Michels, Sabine J. van Dijk, Saskia Schlossarek, Saul Winegrad, Jolanda van der Velden, Dennis Dooijes, Jos M. J. Lamers, Lucie Carrier, Cris dos Remedios, Ger J.M. Stienen
Publikováno v:
van Dijk, S J, Dooijes, D, dos Remedios, C, Michels, M, Lamers, J M J, Winegrad, S, Schlossarek, S, Carrier, L, ten Cate, F J, Stienen, G J M & van der Velden, J 2009, ' Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction ', Circulation, vol. 119, no. 11, pp. 1473-1483 . https://doi.org/10.1161/CIRCULATIONAHA.108.838672
Circulation, 119(11), 1473-1483. Lippincott Williams & Wilkins
Circulation, 119(11), 1473-1483. Lippincott Williams and Wilkins
Circulation, 119(11), 1473-1483. Lippincott Williams & Wilkins
Circulation, 119(11), 1473-1483. Lippincott Williams and Wilkins
Background— Mutations in the MYBPC3 gene, encoding cardiac myosin-binding protein C (cMyBP-C), are a frequent cause of familial hypertrophic cardiomyopathy. In the present study, we investigated whether protein composition and function of the sarco
Autor:
Rien van Haperen, Dirk J. Duncker, Jos M. J. Lamers, Nicky M. Boontje, Jolanda van der Velden, Monique C. de Waard, Rini de Crom, Dick H. W. Dekkers, Diederik W. D. Kuster
Publikováno v:
American Journal of Physiology. Heart and Circulatory Physiology, 296(5), H1513-H1523. American Physiological Society
American Journal of Physiology-Heart and Circulatory Physiology, 296(5), H1513-H1523. American Physiological Society
de Waard, M, van der Velden, J, Boontje, N, Dekkers, D, van Haperen, R, Kuster, D W D, Lamers, J M J, de Crom, R & Duncker, D J 2009, ' Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction ', American Journal of Physiology. Heart and Circulatory Physiology, vol. 296, no. 5, pp. H1513-H1523 . https://doi.org/10.1152/ajpheart.00485.2008
American Journal of Physiology-Heart and Circulatory Physiology, 296(5), H1513-H1523. American Physiological Society
de Waard, M, van der Velden, J, Boontje, N, Dekkers, D, van Haperen, R, Kuster, D W D, Lamers, J M J, de Crom, R & Duncker, D J 2009, ' Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction ', American Journal of Physiology. Heart and Circulatory Physiology, vol. 296, no. 5, pp. H1513-H1523 . https://doi.org/10.1152/ajpheart.00485.2008
de Waard MC, van der Velden J, Boontje NM, Dekkers DH, van Haperen R, Kuster DW, Lamers JM, de Crom R, Duncker DJ. Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction. Am J Physiol
Autor:
Lori A. Walker, Lucie Carrier, Daphne Merkus, Ger J.M. Stienen, Giulia Mearini, Amanda M. G. Versteilen, Judith Krysiak, Nicky M. Boontje, Wolfgang A. Linke, Jos M. J. Lamers, Vincent J. de Beer, Dirk J. Duncker, Ali El-Armouche, Jolanda van der Velden
Publikováno v:
Duncker, D J, Boontje, N, Merkus, D, Versteilen, A M G, Krysiak, J, Mearini, G, El-Armouche, A, de Beer, V J, Lamers, J M J, Carrier, L, Walker, L A, Linke, W A, Stienen, G J M & van der Velden, J 2009, ' Prevention of myofilament dysfunction by beta-blocker therapy in postinfarct remodeling ', Circulation. Heart failure, vol. 2, no. 3, pp. 233-242 . https://doi.org/10.1161/CIRCHEARTFAILURE.108.806125
Circulation. Heart failure, 2(3), 233-242. Lippincott Williams and Wilkins
Circulation-Heart Failure, 2(3), 233-242. Lippincott Williams & Wilkins
Circulation. Heart failure, 2(3), 233-242. Lippincott Williams and Wilkins
Circulation-Heart Failure, 2(3), 233-242. Lippincott Williams & Wilkins
Background— Myofilament contractility of individual cardiomyocytes is depressed in remote noninfarcted myocardium and contributes to global left ventricular pump dysfunction after myocardial infarction (MI). Here, we investigated whether β-blocker
Autor:
Vincent J. de Beer, Daniël A. Pijnappels, Jos M. J. Lamers, Dick H. W. Dekkers, Oana Sorop, Dirk J. Duncker, Frans Boomsma, Daphne Merkus
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology, 294(5), H2069-H2077. American Physiological Society
Several studies have indicated an interaction between the renin-angiotensin (ANG II) system and endothelin (ET) in the regulation of vascular tone. Previously, we have shown that both ET and ANG II exert a vasoconstrictor influence on the coronary re
Autor:
K. Luijk, Karel Bezstarosti, Jeroen Demmers, Nilanjana Maulik, Dick H. W. Dekkers, Jos M. J. Lamers, Dipak K. Das, Adrie J.M. Verhoeven, Erikjan Rijkers, Narasimman Gurusamy
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, 12(5A), 1677-1689. Wiley-Blackwell Publishing Ltd
Journal of Cellular and Molecular Medicine, 12(5A), 1677-1689. Wiley-Blackwell Publishing Ltd
A recent study showed cardioprotective effects of resveratrol on the diabetic heart. The present study sought to compare the protein profiles of the normal versus diabetic hearts after resveratrol treatment using differential proteomic analysis. Rats
Autor:
Daphne Merkus, Ger J.M. Stienen, Jolanda van der Velden, Dirk J. Duncker, R. Zaremba, Nazha Hamdani, Cris dos Remedios, Jos M. J. Lamers, Walter Paulus
Publikováno v:
Proteomics-Clinical Applications, 1(10), 1285-1290. Wiley-VCH Verlag
Zaremba, R, Merkus, D, Hamdani, N, Lamers, J M J, Paulus, W J, dos Remedios, C, Duncker, D J, Stienen, G J M & van der Velden, J 2007, ' Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies ', Proteomics-Clinical Applications, vol. 1, no. 10, pp. 1285-1290 . https://doi.org/10.1002/prca.200600891
Zaremba, R, Merkus, D, Hamdani, N, Lamers, J M J, Paulus, W J, dos Remedios, C, Duncker, D J, Stienen, G J M & van der Velden, J 2007, ' Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies ', Proteomics-Clinical Applications, vol. 1, no. 10, pp. 1285-1290 . https://doi.org/10.1002/prca.200600891
Phosphorylation of cardiac myofilament proteins represents one of the main post-translational mechanisms that regulate cardiac pump function. Human studies are often limited by the amount of available tissue as biopsies taken during cardiac catheteri
Autor:
Ewout J. van den Bos, Olivier C. Manintveld, Jos M. J. Lamers, Pieter D. Verdouw, Dirk J. Duncker, Dick H. W. Dekkers, Maaike te Lintel Hekkert, Grietje M. Suurenbroek
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology, 292, 2563-2565. American Physiological Society
Postconditioning (POC) is known as the phenomenon whereby brief intermittent ischemia applied at the onset of reperfusion following index ischemia limits myocardial infarct size. Whereas there is evidence that the algorithm of the POC stimulus is an
Autor:
Rini de Crom, Liesbeth Biesmans, Jos M. J. Lamers, Kees Schoonderwoerd, Ger J.M. Stienen, Karin R. Sipido, Dick H. W. Dekkers, Virginie Bito, Nicky M. Boontje, Jolanda van der Velden, Monique C. de Waard, Hans Schuurbiers, Dirk J. Duncker, Semir Ozdemir
Publikováno v:
De Waard, M C, Van Der Velden, J, Bito, V, Ozdemir, S, Biesmans, L, Boontje, N M, Dekkers, D H W, Schoonderwoerd, K, Schuurbiers, H C H, De Crom, R, Stienen, G J M, Sipido, K R, Lamers, J M J & Duncker, D J 2007, ' Early exercise training normalizes myofilament function and attenuates left ventricular pump dysfunction in mice with a large myocardial infarction ', Circulation Research, vol. 100, no. 7, pp. 1079-1088 . https://doi.org/10.1161/01.RES.0000262655.16373.37
Circulation Research, 100(7), 1079-1088. Lippincott Williams & Wilkins
Circulation Research, 100(7), 1079-1088. Lippincott Williams and Wilkins
Circulation Research, 100(7), 1079-1088. Lippincott Williams & Wilkins
Circulation Research, 100(7), 1079-1088. Lippincott Williams and Wilkins
The extent and mechanism of the cardiac benefit of early exercise training following myocardial infarction (MI) is incompletely understood, but may involve blunting of abnormalities in Ca 2+ -handling and myofilament function. Consequently, we invest
Autor:
S. Loschen, Heinz-Peter Schultheiss, Isaac Sipo, Jos M. J. Lamers, Volker A. Erdmann, Dick H. W. Dekkers, Stefan Weger, Sandra Pinkert, Roland Vetter, Martin Paul, Henry Fechner, Jens Kurreck, Lennart Suckau, Wolfgang Poller, J. Rekittke, Xiaomin Wang
Publikováno v:
Gene Therapy. 14:211-218
Impaired function of the phospholamban (PLB)-regulated sarcoplasmic reticulum Ca(2+) pump (SERCA2a) contributes to cardiac dysfunction in heart failure (HF). PLB downregulation may increase SERCA2a activity and improve cardiac function. Small interfe
Publikováno v:
Journal of Cellular and Molecular Medicine. 10:896-907
Recent studies demonstrated that resveratrol, a grape-derived polyphenolic phytoalexin, provides pharmacological preconditioning of the heart through a NO-dependent mechanism. To further explore the molecular mechanisms involved in resveratrol-mediat