Uncovering functional signature in neural systems via random matrix theory.

Autor: Assaf Almog, M Renate Buijink, Ori Roethler, Stephan Michel, Johanna H Meijer, Jos H T Rohling, Diego Garlaschelli

Publikováno v: PLoS Computational Biology, Vol 15, Iss 5, p e1006934 (2019)

Neural systems are organized in a modular way, serving multiple functionalities. This multiplicity requires that both positive (e.g. excitatory, phase-coherent) and negative (e.g. inhibitory, phase-opposing) interactions take place across brain modul

Externí odkaz: https://doaj.org/article/778a40aa83364c5591e10d392693fda5

How Old Is Your Brain? Slow-Wave Activity in Non-rapid-eye-movement Sleep as a Marker of Brain Rejuvenation After Long-Term Exercise in Mice

Autor: Maria Panagiotou, Kostas Papagiannopoulos, Jos H. T. Rohling, Johanna H. Meijer, Tom Deboer

Publikováno v: Frontiers in Aging Neuroscience, Vol 10 (2018)

Physical activity is beneficial for health. It has been shown to improve brain functioning and cognition, reduce severity of mood disorders, as well as facilitate healthy sleep and healthy aging. Sleep has been studied in healthy aged mice and absolu

Externí odkaz: https://doaj.org/article/b2dd9d9cbccb4c458a69acf4dc56f8d6

Evidence for Weakened Intercellular Coupling in the Mammalian Circadian Clock under Long Photoperiod.

Autor: M Renate Buijink, Assaf Almog, Charlotte B Wit, Ori Roethler, Anneke H O Olde Engberink, Johanna H Meijer, Diego Garlaschelli, Jos H T Rohling, Stephan Michel

Publikováno v: PLoS ONE, Vol 11, Iss 12, p e0168954 (2016)

For animals living in temperate latitudes, seasonal changes in day length are an important cue for adaptations of their physiology and behavior to the altered environmental conditions. The suprachiasmatic nucleus (SCN) is known as the central circadi

Externí odkaz: https://doaj.org/article/7fa0672d55804906a0d99bf21354f52b

Reduced plasticity in coupling strength in the SCN clock in aging as revealed by Kuramoto modelling

Autor: Anouk W. van Beurden, Stefan Achterhof, Janusz M Meylahn, Jos H. T. Rohling, Johanna H. Meijer

The mammalian circadian clock is located in the suprachiasmatic nucleus (SCN) and consist of a network of coupled neurons, which are entrained to the environmental light-dark cycle. The phase coherence of the neurons is plastic and driven by the leng

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01389b4c9dcb5ab2003ef6d4869c44cb
https://doi.org/10.1101/2021.09.13.460004

Sleep network deterioration as a function of dim-light-at-night exposure duration in a mouse model

Autor: Tom Deboer, Maria Panagiotou, Jos H. T. Rohling

Publikováno v: Clocks & Sleep, 2(3), 308-324. MDPI
Clocks & Sleep; Volume 2; Issue 3; Pages: 308-324
CLOCKS & SLEEP
Clocks & Sleep, Vol 2, Iss 23, Pp 308-324 (2020)
Clocks & Sleep

Artificial light, despite its widespread and valuable use, has been associated with deterioration of health and well-being, including altered circadian timing and sleep disturbances, particularly in nocturnal exposure. Recent findings from our lab re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c705baad920a67218ad7b3545c6f9156
https://hdl.handle.net/1887/3209332