Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jos A. H. Verheugen"'
Autor:
Jos A. H. Verheugen
Publikováno v:
The Journal of Physiology. 508:167-177
1. Human T lymphocytes express both voltage-gated (K(V)) and Ca2+-activated (K(Ca)) potassium channels. The K(Ca) channel is activated by elevations of intracellular Ca2+ ([Ca2+]i) at concentrations attained during physiological Ca2+ signalling. Whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a5d2bf1243bf77e46a46bfabde3959
https://doi.org/10.1111/j.1469-7793.1998.167br.x
https://doi.org/10.1111/j.1469-7793.1998.167br.x
Publikováno v:
The Journal of General Physiology
Voltage-gated n-type K(V) and Ca(2+)-activated K+ [K(Ca)] channels were studied in cell-attached patches of activated human T lymphocytes. The single-channel conductance of the K(V) channel near the resting membrane potential (Vm) was 10 pS with low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82fa5fcaf5eb3b90aa5b624533e03094
https://doi.org/10.1085/jgp.105.6.765
https://doi.org/10.1085/jgp.105.6.765
Publikováno v:
Pflügers Archiv. 426:465-471
Ca(2+)-activated K+ [K(Ca)] channels were studied in excised patches of resting and activated human peripheral blood T lymphocytes. The K(Ca) channel had a single-channel conductance of 50 +/- 6 pS in symmetrical high-K+ solutions in the potential ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b626c70baf036ef14e0607727b1f8883
https://doi.org/10.1007/bf00378523
https://doi.org/10.1007/bf00378523
Publikováno v:
The Journal of physiology. 517
1. The cell-attached configuration of the patch-clamp technique was used to assess resting membrane potential and firing threshold of CA1 pyramidal cells and interneurones of rat hippocampal slices. 2. Resting potential was inferred from the reversal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e8a9a71c2281eb26ed8e8f5bc501fa
https://pubmed.ncbi.nlm.nih.gov/10358119
https://pubmed.ncbi.nlm.nih.gov/10358119
Publikováno v:
Scopus-Elsevier
Neurotransmitters affect the membrane potential (Vm) of target cells by modulating the activity of receptor-linked ion channels. The direction and amplitude of the resulting transmembrane current depend on the resting level ofVmand the gradient acros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16e9b88a7517323507a2c1804a9b588
https://pubmed.ncbi.nlm.nih.gov/10087068
https://pubmed.ncbi.nlm.nih.gov/10087068
Autor:
Jos A. H. Verheugen
Publikováno v:
Signal Transduction — Single Cell Techniques ISBN: 9783642489761
In the cell-attached configuration of the patch-clamp technique (Hamill et al. 1981) currents through ion channels present in the small area under the pipette are measured while the attached cell remains intact and capable of physiological functionin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bae68e2f9fa68e827dabaac5b659ab8
https://doi.org/10.1007/978-3-642-80368-0_14
https://doi.org/10.1007/978-3-642-80368-0_14
Autor:
Henri Korn, Jos A. H. Verheugen
Publikováno v:
The Journal of physiology. 503
1. Changes in the membrane potential (Vm) of human T lymphocytes upon K+ channel block were inferred from alterations in K+ current reversal potential in cell-attached patches. It was found that a high concentration of charybdotoxin (100 nM, CTX), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccdcad36882589c40c6e2198f51aab5e
https://pubmed.ncbi.nlm.nih.gov/9306275
https://pubmed.ncbi.nlm.nih.gov/9306275
Publikováno v:
Cell calcium. 21(1)
T cell receptor (TCR) stimulation, leading to T cell activation and ultimately to cell proliferation and differentiation, evokes elevations of [Ca2+]i with a high variability between individual T lymphocytes. We have used ca2+-imaging of Fura-2 loade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52681fa581d3fcb32db23abd15ac03f
https://pubmed.ncbi.nlm.nih.gov/9056073
https://pubmed.ncbi.nlm.nih.gov/9056073