The Multifaceted Pyruvate Metabolism: Role of the Mitochondrial Pyruvate Carrier

Autor: Joséphine Zangari, Francesco Petrelli, Benoît Maillot, Jean-Claude Martinou

Publikováno v: Biomolecules, Vol 10, Iss 7, p 1068 (2020)

Pyruvate, the end product of glycolysis, plays a major role in cell metabolism. Produced in the cytosol, it is oxidized in the mitochondria where it fuels the citric acid cycle and boosts oxidative phosphorylation. Its sole entry point into mitochond

Externí odkaz: https://doaj.org/article/414dc3df84dc4a2da76a608ef0d04198

Separation and determination of cysteine enantiomers in plasma after derivatization with 4-fluoro-7-nitrobenzofurazan

Autor: Sabrina Ferré, Víctor González-Ruiz, Joséphine Zangari, Sergey Girel, Jean-Claude Martinou, Roccaldo Sardella, Serge Rudaz

Publikováno v: Journal of pharmaceutical and biomedical analysis, Vol. 209 (2022) P. 114539

The importance of D-amino acids in mammals associated with enantio-dependent biological functions has been increasingly highlighted. In addition to naturally occurring, D-amino acid supplementation could have a positive biological impact, including c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4db075f44211a343591d2ddd3f881c5
https://archive-ouverte.unige.ch/unige:158029

MiR-223-3p inhibits angiogenesis and promotes resistance to cetuximab in head and neck squamous cell carcinoma

Autor: Alexandre Bozec, Patrick Brest, Marius Ilie, Thierry Juhel, Salomé Lalvée, Paul Hofman, Mathilde Butori-Pepino, Joséphine Zangari, Valérie Vouret-Craviari, Catherine Butori

Publikováno v: Oncotarget
Oncotarget, 2017, 8 (34), ⟨10.18632/oncotarget.19170⟩
Oncotarget, Impact journals, 2017, 8 (34), ⟨10.18632/oncotarget.19170⟩

MicroRNAs (miRs) participate in tumor growth and dissemination by regulating expression of various target genes. MiR-223-3p is suspected of being involved in head and neck squamous cell carcinoma (HNSCC) growth although its precise role has not been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82e285efa8374a4497b3a416f9a5b75
https://doi.org/10.18632/oncotarget.19170

Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

Autor: Joséphine Zangari, Marius Ilie, Florian Rouaud, Laurie Signetti, Mickaël Ohanna, Robin Didier, Barnabé Roméo, Dana Goldoni, Nicolas Nottet, Cathy Staedel, Jocelyn Gal, Bernard Mari, Baharia Mograbi, Paul Hofman, Patrick Brest

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2018, 46 (7), pp.3813-3814. ⟨10.1093/nar/gky213⟩
Nucleic Acids Research, Oxford University Press, 2017, 8 (34), pp.gkw1284. ⟨10.1093/nar/gkw1284⟩
Nucleic Acids Research, 2017, 8 (34), pp.gkw1284. ⟨10.1093/nar/gkw1284⟩

International audience; Extracellular vesicles (EVs) have been shown to play an important role in intercellular communication as carriers of DNA, RNA and proteins. While the intercellular transfer of miRNA through EVs has been extensively studied, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c15320dcdad925b71f69fe24bfe71c
https://hal.archives-ouvertes.fr/hal-02413532

Abstract 3044: Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

Autor: Robin Didier, Patrick Brest, Mickaël Ohanna, Baharia Mograbi, Dana Goldoni, Barnabé Roméo, Nicolas Nottet, Laurie Signetti, Cathy Staedel, Bernard Mari, Marius Ilie, Paul Hofman, Jocelyn Gal, Florian Rouaud, Joséphine Zangari

Publikováno v: Cancer Research. 77:3044-3044

Background: Extracellular vesicles (EVs) have been shown to play an important role in intercellular communication as carriers of DNA, RNA and proteins. While the intercellular transfer of miRNA thorough EVs has been widely studied, the stability of e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb0ba88ec8f30c5a88bd084352ecafa0
https://doi.org/10.1158/1538-7445.am2017-3044