Zobrazeno 1 - 10
of 32
pro vyhledávání: '"José-Manuel Zaldívar"'
Publikováno v:
In Chaos, Solitons and Fractals 2006 28(3):601-615
Autor:
Gabriele Küsters, Frédéric Y. Bois, Harvey J. Clewell, Eva Maria Collnot, Lucian Romeo Farcal, Walter Diembeck, Ursula Gundert-Remy, Emanuela Testai, Kannan Krishnan, Liesbeth Geraets, Klaus Schröder, George Loizou, Iwona Wilk-Zasadna, Camilla Bernasconi, J.G.M. Bessems, José Manuel Zaldívar-Comenges, Sofia B. Leite, Nynke I. Kramer, Sandra Coecke, Olavi Pelkonen
Publikováno v:
Regulatory Toxicology and Pharmacology; Vol 68
Regulatory Toxicology and Pharmacology
Regulatory Toxicology and Pharmacology
Information on toxicokinetics is critical for animal-free human risk assessment. Human external exposure must be translated into human tissue doses and compared with in vitro actual cell exposure associated to effects (in vitro-in vivo comparison). D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6189b3581a49ac10fbaccd39637bd503
https://doi.org/10.1016/j.yrtph.2013.11.008
https://doi.org/10.1016/j.yrtph.2013.11.008
Autor:
José-Manuel Zaldívar-Comenges, Daniel Neagu, Mark T. D. Cronin, Elena Fioravanzo, Chihae Yang, Andrea-Nicole Richarz, Michael R. Berthold
Publikováno v:
International Journal of Toxicology. 32:58-88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d76e127cb0c61c4f1e9b6ef056c4373
https://doi.org/10.1177/1091581812471490
https://doi.org/10.1177/1091581812471490
Autor:
Fabiano Reniero, José Manuel Zaldívar, Matteo Politi, Maurice Whelan, Bibiana Scelfo, Taina Palosaari
Publikováno v:
Toxicology. 299:172-183
Cortical neurons grown on multi electrode array (MEA) chips have been shown to be a valuable alternative method to study electrophysiological properties of the central nervous system and to perform functional toxicological screening. Here we studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92700c88f92abcea70a3ac6ae3b26cb2
https://doi.org/10.1016/j.tox.2012.05.020
https://doi.org/10.1016/j.tox.2012.05.020
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
We analyze the joint effect of contaminants and nutrient loading on population dynamics of marine food chains by means of bifurcation analysis. Contaminant toxicity is assumed to alter mortality of some species with a sigmoidal dose¿response relatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c864f14c86637091c6e478aaf0ff78e
https://doi.org/10.1016/j.mbs.2008.12.002
https://doi.org/10.1016/j.mbs.2008.12.002
Autor:
G. Umlauf, Giovanni Locoro, Alfred de Jager, Robert Loos, Jan Wollgast, Eugen H. Christoph, Georg Hanke, Tania Huber, José-Manuel Zaldívar, Bernd Manfred Gawlik
Publikováno v:
Chemosphere. 71:306-313
C7-C11 perfluorinated carboxylates (PFACs) and perfluorooctansulfonate (PFOS) were analysed in selected stretches of the River Po and its major tributaries. Analyses were performed by solid-phase extraction (SPE) with Oasis HLB cartridges and methano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3475ab3528ab36792d27d24fc8ac67ec
https://doi.org/10.1016/j.chemosphere.2007.09.022
https://doi.org/10.1016/j.chemosphere.2007.09.022
Autor:
Jos G, Bessems, George, Loizou, Kannan, Krishnan, Harvey J, Clewell, Camilla, Bernasconi, Frederic, Bois, Sandra, Coecke, Eva-Maria, Collnot, Walter, Diembeck, Lucian Romeo, Farcal, Liesbeth, Geraets, Ursula, Gundert-Remy, Nynke, Kramer, Gabriele, Küsters, Sofia B, Leite, Olavi R, Pelkonen, Klaus, Schröder, Emanuela, Testai, Iwona, Wilk-Zasadna, José-Manuel, Zaldívar-Comenges
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 68(1)
Information on toxicokinetics is critical for animal-free human risk assessment. Human external exposure must be translated into human tissue doses and compared with in vitro actual cell exposure associated to effects (in vitro-in vivo comparison). D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1e9dd227b572883ece17818fa459f61
https://pubmed.ncbi.nlm.nih.gov/24287156
https://pubmed.ncbi.nlm.nih.gov/24287156
We have developed an integrated model that couples a fate model with a cell growth model and a toxic effect model to analyze the dynamics of cell populations when subject to a toxicant in cell-based assays experiments. The model has been used to anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8d5313e9d9b8519893ca98a01ccb074
https://doi.org/10.1016/b978-0-444-59396-2.00004-3
https://doi.org/10.1016/b978-0-444-59396-2.00004-3
Publikováno v:
Expert opinion on drug metabolismtoxicology. 6(7)
The methods and tools of computational toxicology form an essential and integrating pillar in the new paradigm of predictive toxicology, which seeks to develop more efficient and effective means of assessing chemical toxicity, while also reducing ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1a26832b0648fb474365f147a26db4
https://pubmed.ncbi.nlm.nih.gov/20443752
https://pubmed.ncbi.nlm.nih.gov/20443752