Bacteriophages Combined With Subtherapeutic Doses of Flucloxacillin Act Synergistically Against Staphylococcus aureus Experimental Infective Endocarditis

Autor: Jonathan Save, Yok‐Ai Que, José M. Entenza, Camille Kolenda, Frédéric Laurent, Grégory Resch

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 3 (2022)

Background The potential of phage therapy for the treatment of endovascular Staphylococcus aureus infections remains to be evaluated. Methods and Results The efficacy of a phage cocktail combining Herelleviridae phage vB_SauH_2002 and Podoviriae phag

Externí odkaz: https://doaj.org/article/146a5aae6d9041bfa9523061757f8e6b

Solar photo-Fenton disinfection of 11 antibiotic-resistant bacteria (ARB) and elimination of representative AR genes. Evidence that antibiotic resistance does not imply resistance to oxidative treatment

Autor: José M. Entenza, Truong-Thien Melvin Le, Stefanos Giannakis, Cesar Pulgarin

Publikováno v: Water Research

The emergence of antibiotic resistance represents a major threat to human health. In this work we investigated the elimination of antibiotic resistant bacteria (ARB) by solar light and solar photo-Fenton processes. As such, we have designed an experi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cec4e404fe4261f4b4493dfbb9020cb
https://doi.org/10.1016/j.watres.2018.06.062

In Vitro and In Vivo Effectiveness of an Innovative Silver-Copper Nanoparticle Coating of Catheters To Prevent Methicillin-Resistant Staphylococcus aureus Infection

Autor: Cesar Pulgarin, José M. Entenza, Nancy B. Hopf, Aurélie Berthet, Sami Rtimi, John Kiwi, Alain Bizzini, Philippe Moreillon, Myriam K. S. Ballo

Publikováno v: Antimicrobial Agents and Chemotherapy, vol. 60, no. 9, pp. 5349-5356

In this study, silver/copper (Ag/Cu)-coated catheters were investigated for their efficacy in preventing methicillin-resistant Staphylococcus aureus (MRSA) infection in vitro and in vivo . Ag and Cu were sputtered (67/33% atomic ratio) on polyurethan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88c6540a69cea84f21a08d8b91e9a63
https://doi.org/10.1128/aac.00959-16

Marginal role of von Willebrand factor-binding protein and coagulase in the initiation of endocarditis in rats with catheter-induced aortic vegetations

Autor: Dominique Missiakas, Ruth Heying, Olaf Schneewind, Thomas Vanassche, Yok-Ai Que, Jorien Claes, José M. Entenza, Carmen Menzi, Stefano Mancini, Frank Oechslin, Philippe Moreillon, Tiago Rafael Veloso

Publikováno v: Virulence
Mancini, Stefano; Oechslin, Frank; Menzi, Carmen; Que, Yok Ai; Claes, Jorien; Heying, Ruth; Veloso, Tiago Rafael; Vanassche, Thomas; Missiakas, Dominique; Schneewind, Olaf; Moreillon, Philippe; Entenza, José Manuel (2018). Marginal role of von Willebrand factor-binding protein and coagulase in the initiation of endocarditis in rats with catheter-induced aortic vegetations. Virulence, 9(1), pp. 1615-1624. Taylor & Francis 10.1080/21505594.2018.1528845
Virulence, vol. 9, no. 1, pp. 1615-1624
Virulence, Vol 9, Iss 1, Pp 1615-1624 (2018)

Staphylococcus aureus is the leading cause of infective endocarditis (IE). While the role of S. aureus cell-wall associated protein clumping factor A (ClfA) in promoting IE has been already demonstrated, that of the secreted plasma-clotting factors s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff946c289404e5e02016b98d2e981e9

In Vivo Effect of Flucloxacillin in Experimental Endocarditis Caused by mecC -positive Staphylococcus aureus Showing Temperature-Dependent Susceptibility In Vitro

Autor: Frédéric Laurent, François Vandenesch, Jacques Vouillamoz, Stefano Mancini, Marlyse Giddey, Philippe Moreillon, José M. Entenza, Tiago Rafael Veloso

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2015, 59 (4), pp.2435-2438. ⟨10.1128/AAC.04733-14⟩
Antimicrobial Agents and Chemotherapy, 2015, 59 (4), pp.2435-2438. ⟨10.1128/AAC.04733-14⟩

Methicillin-resistant Staphylococcus aureus (MRSA) carrying the mecC gene ( mecC -MRSA) exhibited at 37°C MICs of oxacillin close to those of methicillin-susceptible S. aureus (MSSA). We investigated whether at this temperature, mecC -MRSA strains r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0db6f5efcde05182cac3f28e026675
https://doi.org/10.1128/aac.04733-14