Zobrazeno 1 - 10
of 111
pro vyhledávání: '"José-Jesús Fernández"'
Autor:
Eva Martin-Solana, Laura Casado-Zueras, Teobaldo E. Torres, Gerardo F. Goya, Maria-Rosario Fernandez-Fernandez, Jose-Jesus Fernandez
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by an expanded CAG repeat in the coding sequence of huntingtin protein. Initially, it predominantly affects medium-sized spiny neurons (MSSNs) of the corpus striat
Externí odkaz:
https://doaj.org/article/ce50578ff06d4d418cb296592d3d2c64
Autor:
Ginés Ávila‐Pérez, María Teresa Rejas, Francisco Javier Chichón, Milagros Guerra, José Jesús Fernández, Dolores Rodríguez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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Plus-stranded RNA viruses replicate in the cytosol of infected cells, in membrane-bound replication complexes. We previously identified double membrane vesicles (DMVs) in the cytoplasm of cells infected with Berne virus (BEV), the prototype member of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7deb18ea4ad2b43e13584e610cc9c489
http://hdl.handle.net/10261/279578
http://hdl.handle.net/10261/279578
Autor:
Isabel Fernández de Castro, Paula F. Zamora, Laura Ooms, José Jesús Fernández, Caroline M.-H. Lai, Bernardo A. Mainou, Terence S. Dermody, Cristina Risco
Publikováno v:
mBio, Vol 6, Iss 1 (2015)
Externí odkaz:
https://doaj.org/article/38db1451653c4333b20dd4b5c4c92f0e
Autor:
Isabel Fernández de Castro, Paula F. Zamora, Laura Ooms, José Jesús Fernández, Caroline M.-H. Lai, Bernardo A. Mainou, Terence S. Dermody, Cristina Risco
Publikováno v:
mBio, Vol 5, Iss 1 (2014)
ABSTRACT Most viruses that replicate in the cytoplasm of host cells form neo-organelles that serve as sites of viral genome replication and particle assembly. These highly specialized structures concentrate viral replication proteins and nucleic acid
Externí odkaz:
https://doaj.org/article/952e8d58d4b44885b7992df855b66cd1
Autor:
Eva Martin-Solana, Irene Diaz-Lopez, Yamina Mohamedi, Ivan Ventoso, Jose-Jesus Fernandez, Maria Rosario Fernandez-Fernandez
Publikováno v:
Neurobiology of Disease, Vol 195, Iss , Pp 106488- (2024)
Given their highly polarized morphology and functional singularity, neurons require precise spatial and temporal control of protein synthesis. Alterations in protein translation have been implicated in the development and progression of a wide range
Externí odkaz:
https://doaj.org/article/1c6a58c940e74cd48db0cbbcab08e5a8
Publikováno v:
Bio Protoc
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Mammalian orthoreoviruses (reoviruses) are nonenveloped, double-stranded RNA viruses that replicate and assemble in cytoplasmic membranous organelles called viral inclusions (VIs). To define the cellular compartments involved in nonlytic reovirus egr
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48261 (2012)
Tomography allows elucidation of the three-dimensional structure of an object from a set of projection images. In life sciences, electron microscope tomography is providing invaluable information about the cell structure at a resolution of a few nano
Externí odkaz:
https://doaj.org/article/b4dd33737c3c48f1933a9216d8cf6876
Autor:
Gerardo F. Goya, Maria-Rosario Fernandez-Fernandez, José-Jesús Fernández, Teobaldo E. Torres, Eva Martin-Solana
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
[Summary]: We have developed a software tool to improve the image quality in focused ion beam–scanning electron microscopy (FIB–SEM) stacks: PolishEM. Based on a Gaussian blur model, it automatically estimates and compensates for the blur affecti
Publikováno v:
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recently, it has been shown that the resolution in cryo-tomography could be improved by considering the sample motion in tilt-series alignment and reconstruction, where a set of quadratic polynomials were used to model this motion. One requirement of