Zobrazeno 1 - 10
of 16
pro vyhledávání: '"José do Espírito Santo Junior"'
Autor:
José do Espírito Santo Junior, Josué Lacerda de Souza, Lener Santos da Silva, Cilana Chagas da Silva, Tuanny Arruda do Nascimento, Mara Lúcia Gomes de Souza, Alyne Farias da Cunha, Jacqueline da Silva Batista, José Pereira de Moura Neto, Marcus Vinitius de Farias Guerra, Rajendranath Ramasawmy
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionLeishmaniasis continues to pose a substantial health burden in 97 countries worldwide. The progression and outcome of Leishmania infection are influenced by various factors, including the cytokine milieu, the skin microbiota at the infect
Externí odkaz:
https://doaj.org/article/d40aefb16e124342829061094db7b5ee
Autor:
Héctor David Graterol Sequera, Josué Lacerda de Souza, José do Espírito Santo Junior, Lener Santos da Silva, Suzana Kanawati Pinheiro, Herllon Karllos Athaydes Kerr, Mara Lúcia Gomes de Souza, Marcus Vinitius de Farias Guerra, Tirza Gabrielle Ramos de Mesquita, Rajendranath Ramasawmy
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 6, p e0011416 (2023)
Nucleotide-binding oligomerization domain, leucine-rich repeat-containing protein family (NLR) are intracellular pathogen recognition receptors mediating innate immunity, releasing proinflammatory cytokines IL-1β and IL-18, and promoting pyroptotic
Externí odkaz:
https://doaj.org/article/1b722904eee64bfc9feb753907eddcf2
Autor:
Tirza Gabrielle Ramos de Mesquita, José do Espírito Santo Junior, Josué Lacerda de Souza, Lener Santos da Silva, Tuanny Arruda do Nascimento, Mara Lúcia Gomes de Souza, Marcus Vinitius de Farias Guerra, Rajendranath Ramasawmy
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
Leishmaniases, a group of vector-borne diseases, are caused by the protozoan intracellular parasite Leishmania (L.) and are transmitted by the phlebotomine sandflies. A wide range of clinical manifestations in L- infection is observed. The clinical o
Externí odkaz:
https://doaj.org/article/b070758debab46c1af3279e1d2207771
Autor:
Tirza Gabrielle Ramos de Mesquita, José do Espírito Santo Junior, Luan Diego Oliveira da Silva, George Allan Villarouco Silva, Felipe Jules de Araújo, Suzana Kanawati Pinheiro, Herllon Karllos Athaydes Kerr, Lener Santos da Silva, Luciane Macedo de Souza, Samir Assad de Almeida, Krys Layane Guimarães Duarte Queiroz, Josué Lacerda de Souza, Cilana Chagas da Silva, Héctor David Graterol Sequera, Mara Lúcia Gomes de Souza, Anderson Nogueira Barbosa, Gemilson Soares Pontes, Marcus Vinitius de Farias Guerra, Rajendranath Ramasawmy
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The immunopathology associated with Leishmaniasis is a consequence of inflammation. Upon infection with Leishmania, the type of host-immune response is determinant for the clinical manifestations that can lead to either self-healing or chronic diseas
Externí odkaz:
https://doaj.org/article/118631cf6fba4aaea63ed666c7b1e8dd
Autor:
Tirza Gabrielle Ramos de Mesquita, José do Espírito Santo Junior, Thais Carneiro de Lacerda, Krys Layane Guimarães Duarte Queiroz, Cláudio Marcello da Silveira Júnior, José Pereira de Moura Neto, Lissianne Augusta Matos Gomes, Mara Lúcia Gomes de Souza, Marcus Vinitius de Farias Guerra, Rajendranath Ramasawmy
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009795 (2021)
Leishmania are intracellular protozoan parasites that cause a wide spectrum of clinical manifestations in genetically susceptible individuals with an insufficient or balanced Th1 immune response to eliminate the parasite. MiRNAs play important regula
Externí odkaz:
https://doaj.org/article/04dded1909ba430584690d690bcb8879
Autor:
Rajendranath Ramasawmy, José do Espírito Santo Junior, Thais Carneiro de Lacerda, Krys Layane Guimarães Duarte Queiroz, Tirza Gabrielle Ramos de Mesquita, Cláudio Marcello da Silveira Júnior, Mara Lúcia Gomes de Souza, Marcus Vinitius de Farias Guerra, Lissianne Augusta Matos Gomes, José Pereira de Moura Neto
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009795 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009795 (2021)
Leishmania are intracellular protozoan parasites that cause a wide spectrum of clinical manifestations in genetically susceptible individuals with an insufficient or balanced Th1 immune response to eliminate the parasite. MiRNAs play important regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123edc9a7eec8c100f18d25320a1d0a2
http://europepmc.org/articles/PMC8483412
http://europepmc.org/articles/PMC8483412
Autor:
Anette Chrusciak Talhari, José do Espírito Santo Junior, George Allan Villarouco da Silva, Felipe Gomes Naveca, Sinésio Talhari, Rajendranath Ramasawmy, Tirza Gabrielle Ramos de Mesquita, Mara Lúcia Gomes de Souza, Victor Costa de Souza
Publikováno v:
Clinical Infectious Diseases. 71:274-281
Background Interferon-γ (IFN-γ) plays an important role in the control of Leishmania infection. Blockade of IFN-γ signaling in mice increases lesion size and parasite load. In endemic areas of Leishmaniasis, only a fraction of the population devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485bab15d1c0250e20a760229e2cd127
https://doi.org/10.1093/cid/ciz810
https://doi.org/10.1093/cid/ciz810
Autor:
Felipe Jules de Araújo Santos, Tirza Gabrielle Ramos de Mesquita, Rajendranath Ramasawmy, José do Espírito Santo Junior, Moacir Couto de Andrade Júnior, Sinésio Talhari, Mara Lúcia Gomes de Souza, Lener Santos da Silva
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220572 (2019)
PLoS ONE
Repositório Institucional do INPA
Instituto Nacional de Pesquisas da Amazônia (INPA)
instacron:INPA
PLoS ONE
Repositório Institucional do INPA
Instituto Nacional de Pesquisas da Amazônia (INPA)
instacron:INPA
Leishmaniasis is a disease caused by intracellular protozoan parasites of the genus Leishmania. In endemic areas, only a portion of exposed subjects develops cutaneous leishmaniasis (CL), suggesting that the genetic inheritance of the host plays a vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679b67017f7d8db9bc269d8be52f6a01
https://doaj.org/article/102f5205f2da4164bd943fc35d114e5f
https://doaj.org/article/102f5205f2da4164bd943fc35d114e5f
Autor:
Mara Lúcia Gomes de Souza, Diogo Matos dos Santos, Krys Layane Guimarães Duarte Queiroz, Rajendranath Ramasawmy, Cláudio Marcello da Silveira Júnior, Cilana Chagas da Silva, Marcus Vinitius de Farias Guerra, Thais Carneiro de Lacerda, Lener Santos da Silva, Luan Diego Oliveira da Silva, José do Espírito Santo Junior, Héctor David Graterol Sequera, Felipe Jules de Araújo, Melissa Tamayo Hermida, Tirza Gabrielle Ramos de Mesquita, Josué Lacerda de Souza
Publikováno v:
Pathogens
Pathogens, Vol 10, Iss 498, p 498 (2021)
Volume 10
Issue 4
Pathogens, Vol 10, Iss 498, p 498 (2021)
Volume 10
Issue 4
Background: Leishmaniasis is an infectious disease caused by Leishmania parasites. A Th1 immune response is necessary in the acute phase to control the pathogen. The triggering receptor expressed on myeloid cells (TREM)-1 is a potent amplifier of inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4208c222634ae5aee4046c9678c4cb
https://doi.org/10.3390/pathogens10040498
https://doi.org/10.3390/pathogens10040498
Autor:
Mara Lúcia Gomes de Souza, Karolina da Costa Sabino, Tirza Gabrielle Ramos de Mesquita, Helia Valeria de Souza Encarnação, George Allan Villarouco da Silva, Rajendranath Ramasawmy, Salim Assad de Almeida, José do Espírito Santo Junior, Isaac de Aguiar Neres, Sinésio Talhari
Publikováno v:
Cytokine. 123
Nod-like Receptor Protein3 (NLRP3) inflammasome in macrophages infected with Leishmania sp. enhances the secretion of IL-1β. Excess IL-1β production is linked to disease severity in patients with cutaneous leishmaniasis (CL) caused by L. mexicana.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0de8380068a3b6140f8695223702b7
https://pubmed.ncbi.nlm.nih.gov/31357078
https://pubmed.ncbi.nlm.nih.gov/31357078