Zobrazeno 1 - 10
of 23
pro vyhledávání: '"José Wojnacki"'
Autor:
José Wojnacki, Agustin Leonardo Lujan, Nathalie Brouwers, Carla Aranda-Vallejo, Gonzalo Bigliani, Maria Pena Rodriguez, Ombretta Foresti, Vivek Malhotra
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Agonist-mediated stimulated pathway of mucin and insulin release are biphasic in which rapid fusion of pre-docked granules is followed by slow docking and fusion of granules from the reserve pool. Here, based on a cell-culture system, we sho
Externí odkaz:
https://doaj.org/article/9b2132b2ff3a4a458a28b0f01ddcf96b
Autor:
Francesca Filippini, Sébastien Nola, Ahmed Zahraoui, Kevin Roger, Mansoore Esmaili, Ji Sun, José Wojnacki, Anaïs Vlieghe, Philippe Bun, Stéphanie Blanchon, Jean-Christophe Rain, Jean-Marc Taymans, Marie-Christine Chartier-Harlin, Chiara Guerrera, Thierry Galli
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112221- (2023)
Summary: The neuropeptide VGF was recently proposed as a neurodegeneration biomarker. The Parkinson’s disease-related protein leucine-rich repeat kinase 2 (LRRK2) regulates endolysosomal dynamics, a process that involves SNARE-mediated membrane fus
Externí odkaz:
https://doaj.org/article/c86cc19d59e746bf9eff4fe608506af2
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100713- (2021)
Summary: Autophagy is being involved in an increasing number of cellular pathways. It now appears that autophagy stimulation and inhibition have complex effects in neurons. Here, we present a simple yet powerful protocol to induce autophagy in primar
Externí odkaz:
https://doaj.org/article/7e035b0e786e46009c9c38ba0481d231
Autor:
José Wojnacki, Sébastien Nola, Philippe Bun, Béatrice Cholley, Francesca Filippini, Mary T. Pressé, Joanna Lipecka, Sin Man Lam, Julie N’guyen, Axelle Simon, Amine Ouslimani, Guanghou Shui, Claudio Marcelo Fader, Maria Isabel Colombo, Ida Chiara Guerrera, Thierry Galli
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 109006- (2021)
Externí odkaz:
https://doaj.org/article/25c08b9fe46a44d191289e20e498f994
Autor:
Ritobrata Ghose, Álvaro Aranguren-Ibáñez, Niccolò Arecco, Diego Balboa, Marc Bataller, Sergi Beltran, Hannah Benisty, Angèle Bénard, Edgar Bernardo, Sílvia Carbonell Sala, Eloi Casals, Ludovica Ciampi, Livia Condemi, Alberto Corvó, Marta Cosín-Tomás, Mirabai Cuenca-Ardura, Juan Manuel Duran Serrano, María Isabel Espejo Díaz, Marcos Fernandez Callejo, Antoni Gañez-Zapater, Raquel Garcia-Castellanos, Romina Garrido, Gil Henkin, Toni Hermoso Pulido, Xavier Hernandez-Alias, Jorge Herrero Vicente, Matthew Ingham, Wei Ming Lim, Sílvia Llonch, Elena Marmesat Bertoli, Irene Miguel-Escalada, Ariadna Montero-Blay, Cristina Navarrete Hernández, Maria Victoria Neguembor, Róisín-Ana Ní Chárthaigh, Natalia Pardo-Lorente, Laura Pascual-Reguant, Sílvia Pérez-Lluch, Reyes Perza, Martina Pesaresi, Daniel Picó Amador, Paula Pifarré, Davide Piscia, Marcos Plana-Carmona, Julia Ponomarenko, Leandro Radusky, Ezequiel Rivero, Malgorzata Rogalska, Guillem Torcal Garcia, José Wojnacki
Publikováno v:
F1000Research, Vol 9 (2020)
The COVID-19 pandemic has posed and is continuously posing enormous societal and health challenges worldwide. The research community has mobilized to develop novel projects to find a cure or a vaccine, as well as to contribute to mass testing, which
Externí odkaz:
https://doaj.org/article/a31f23efbb70401e91a65643d3267f89
Autor:
José Wojnacki, Gonzalo Quassollo, Martín D. Bordenave, Nicolás Unsain, Gaby F. Martínez, Alan M. Szalai, Olivier Pertz, Gregg G. Gundersen, Francesca Bartolini, Fernando D. Stefani, Alfredo Cáceres, Mariano Bisbal
RhoA plays a crucial role in neuronal polarization, where its action restraining axon outgrowth has been thoroughly studied. We now report that RhoA has not only inhibitory but also a stimulatory effect on axon development depending on when and where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da46eee82bde32439f91a5e2ea6f6e3f
https://doi.org/10.1101/2023.04.17.537156
https://doi.org/10.1101/2023.04.17.537156
Autor:
Patryk Poliński, Marta Miret Cuesta, Alfonsa Zamora-Moratalla, Federica Mantica, Gerard Cantero-Recasens, Davide Normanno, Luis Iñiguez Rabago, Cruz Morenilla-Palao, Patricia Ordoño, Sophie Bonnal, Raúl Gómez Riera, María Martínez De Lagrán Cabredo, Álvaro Fernández-Blanco, Cristina Rodríguez-Marin, Jon Permanyer, Orsolya Fölsz, Cesar Sierra, Diana Legutko, José Wojnacki, Juan Luis Musoles Lleo, Eloisa Herrera, Mara Dierssen, Manuel Irimia
Actin cytoskeleton dynamics is crucial for neurogenesis and neuronal function. Precise quantitative and qualitative regulation of actin polymerization is achieved by multiple actin-binding proteins, among which formins are particularly versatile. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36c323d7dfd5e612f2958e4c1a1d2072
https://doi.org/10.1101/2023.01.12.523772
https://doi.org/10.1101/2023.01.12.523772
Publikováno v:
STAR Protocols
STAR Protocols, Elsevier, 2021, 2 (3), pp.100713. ⟨10.1016/j.xpro.2021.100713⟩
STAR Protocols, Vol 2, Iss 3, Pp 100713-(2021)
STAR Protocols, Elsevier, 2021, 2 (3), pp.100713. ⟨10.1016/j.xpro.2021.100713⟩
STAR Protocols, Vol 2, Iss 3, Pp 100713-(2021)
Summary Autophagy is being involved in an increasing number of cellular pathways. It now appears that autophagy stimulation and inhibition have complex effects in neurons. Here, we present a simple yet powerful protocol to induce autophagy in primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9ca41f39d861b205c98d07588af97e
https://www.hal.inserm.fr/inserm-03324816
https://www.hal.inserm.fr/inserm-03324816
Autor:
Ahmed Zahraoui, Jean-Christophe Rain, José Wojnacki, Francesca Filippini, Sébastien Nola, Kevin Roger, Chiara Guerrera, Stephanie Blachon, Philippe Bun, Marie-Christine Chartier-Harlin, Thierry Galli, Jean-Marc Taymans
Publikováno v:
SSRN Electronic Journal.
LRRK2 was suggested to regulate endolysosomal dynamics, a process which relies particularly on membrane fusion mediated by SNAREs. Here we investigated the biochemical links between LRRK2 and v-SNAREs and their potential cellular functions. We found
Autor:
José Wojnacki, Cédric Delevoye, Chiara Guerrera, Claudio Marcelo Fader, Amine Ouslimani, Joanna Lipecka, Sébastien Nola, María Isabel Colombo, Thierry Galli, Béatrice Cholley, Philippe Bun, Mary T. Pressé
Publikováno v:
SSRN Electronic Journal.
VAMP7 is involved in autophagy and exocytosis mediating neurite growth, two yet unconnected cellular pathways. Here we show the occurrence of combined VAMP7/ATG9 secretory events. VAMP7/LC3- and VAMP7/ATG9-positive vesicles moved anterogradely along