Zobrazeno 1 - 10
of 16
pro vyhledávání: '"José W, Rodríguez"'
Autor:
Lizabeth Giménez Moreira, José W. Rodríguez, Gabriela Ortiz Soto, Karolyna Rosado, Néstor M. Carballeira, Elsie A. Orellano, Rafael Victorio Carvalho Guido, Adriano D. Andricopulo, David J. Sanabria-Ríos
Publikováno v:
Lipids. 50:1043-1050
The natural fatty acids (5Z)-5-pentacosenoic and (9Z)-9-pentacosenoic acids were synthesized for the first time in eight steps starting from either 4-bromo-1-butanol or 8-bromo-1-butanol and in 20-58% overall yields, while the novel fatty acids 5-pen
Autor:
Christian Velez, Gabriela Ortiz-Soto, David J. Sanabria-Ríos, Beatriz Zayas, Néstor M. Carballeira, Joanne S. Altieri-Rivera, Félix Álvarez-Colón, Eddy Ríos-Olivares, Camille Ríos, Victor Serrano, José W. Rodríguez, R. Gutiérrez, Joshua Rosario, Yaritza Rivera-Torres
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:2174-2180
The first synthesis of C5-curcumin-fatty acid (C5-Curc-FA) conjugates was successfully performed. Through a two-step synthetic route, 10 analogs were synthesized for a structure–activity relationship (SAR) study. It was found that C5-Curc-FA conjug
Autor:
Sophia La Banca de Oliveira, José W. Rodríguez, Vesna A. Eterovic, Cleber A. Trujillo, P.A. Ferchmin, Priscilla D. Negraes, Nawal M. Boukli, Luis A. Cubano, Verónica O Berríos, Telma T. Schwindt, Henning Ulrich, Antonio H. Martins
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Acetylcholinesterase (AChE) inhibition has been described as the main mechanism of organophosphate (OP)-evoked toxicity. OPs represent a human health threat, because chronic exposure to low doses can damage the developing brain, and acute exposure ca
Autor:
Camille Ríos, José W. Rodríguez, Gabriel A. Cintrón, Gamalier Maldonado-Domínguez, Eddy Ríos-Olivares, Idializ Domínguez, Nashbly Montano, Joanne S. Altieri-Rivera, Néstor M. Carballeira, Damarith Díaz, David J. Sanabria-Ríos, Yaritza Rivera-Torres
Publikováno v:
Chemistry and Physics of Lipids. 178:84-91
The first study aimed at determining the structural characteristics needed to prepare antibacterial 2-alkynoic fatty acids (2-AFAs) was accomplished by synthesizing several 2-AFAs and other analogues in 18-76% overall yields. Among all the compounds
Autor:
José W. Rodríguez, Nawal M. Boukli, Luis A. Cubano, Zainulabedin M. Saiyed, Martha Ricaurte, Madhavan Nair, Eddy Ríos Olivares
Publikováno v:
Alcoholism: Clinical and Experimental Research. 34:2081-2088
Background: Dendritic cells (DCs) are responsible for the activation of T cells and B cells. There is accumulating evidence that psychoactive substances such as alcohol can affect immune responses. We hypothesize that this occurs by modulating change
Autor:
Zainulabedin M. Saiyed, Madhavan Nair, Kurapati V. K. Rao, Dakshayani Kadiyala Babu, Alain Diaz, Thangavel Samikkannu, José W. Rodríguez
Publikováno v:
Alcoholism: Clinical and Experimental Research. 33:1731-1738
Alcohol is the most widely abused substance and its chronic consumption causes neurobehavioral disorders. It has been shown that alcohol affects the function of immune cells. Dendritic cells (DC) serve as the first line of defense against infections
Differential Regulation of Indoleamine-2,3-Dioxygenase (IDO) by HIV Type 1 Clade B and C Tat Protein
Autor:
José W. Rodríguez, Madhavan Nair, Zainulabedin M. Saiyed, Dakshayani Kadiyala Babu, Kurapati V. K. Rao, Thangavel Samikkannu, Marina N. Papuashvili
Publikováno v:
AIDS Research and Human Retroviruses. 25:329-335
Previous studies have demonstrated that infection with HIV-1 clades might differentially contribute to the neuropathogenesis of HIV-1-associated dementia (HAD). HIV-1 transactivator regulatory protein (Tat) plays a major role in the process of disrup
Autor:
Manuel Delgado-Vélez, Yarelis Robles, Eddy Ríos-Olivares, José W. Rodríguez, Irmarie Morales, Ana M. Lugo-Chinchilla, Nimaris Bruno, Fernando L. Renaud, Luis Lizardo, Miguel Correa
Publikováno v:
Journal of Neuroimmunology. 196:94-100
We have shown previously that whereas acute exposure of cultured murine peritoneal macrophages inhibits phagocytosis, chronic exposure results in a putative tolerant/dependent state. We now report similar observations using human cultured monocyte-de
Autor:
José W. Rodríguez, Nawal M. Boukli, Luis A. Cubano, Robert L. Hunter, Miguel Otero, Eddy Ríos-Olivares, María C. Ocasio, Madhavan Nair, Nat O. Pagan, Zilka Ríos
Publikováno v:
American Journal of Infectious Diseases. 3:267-275
Partial immune restoration may be obtained with highly active antiretroviral therapy (HAART), but specific anti-HIV-1 immune responses do not appear to improve substantially. We have demonstrated that a soluble factor(s) induced by a mixture of inact
Autor:
José W. Rodríguez, Nawal M. Boukli, Luis A. Cubano, Eddy Ríos-Olivares, Griselle Font, Luis Aguilera Rodríguez, Robert L. Hunter, Miguel Otero, Madhavan Nair
Publikováno v:
American Journal of Infectious Diseases. 3:208-216
CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been