Zobrazeno 1 - 10
of 45
pro vyhledávání: '"José Trincão"'
Autor:
Emma V. Beale, Anna J. Warren, José Trincão, James Beilsten-Edmands, Adam D. Crawshaw, Geoff Sutton, David Stuart, Gwyndaf Evans
Publikováno v:
IUCrJ, Vol 7, Iss 3, Pp 500-508 (2020)
Developing methods to determine high-resolution structures from micrometre- or even submicrometre-sized protein crystals has become increasingly important in recent years. This applies to both large protein complexes and membrane proteins, where prot
Externí odkaz:
https://doaj.org/article/97953cece9ad46f69d67226b4d3ea88b
Autor:
David I. Stuart, Gwyndaf Evans, Adam D. Crawshaw, Anna J. Warren, Emma V Beale, James Beilsten-Edmands, Geoff Sutton, José Trincão
Publikováno v:
IUCrJ
IUCrJ, Vol 7, Iss 3, Pp 500-508 (2020)
IUCrJ, Vol 7, Iss 3, Pp 500-508 (2020)
Protein crystals exposed to a scanning electron microscope beam were analysed using X-ray diffraction to assess the impact of electrons on crystal quality. These experiments support the use of a scanning electron microscope as an imaging tool for loc
Autor:
Graham Duller, Andrew Stallwood, Emma V Beale, Gwyndaf Evans, José Trincão, Adam D. Crawshaw, Anna J. Warren
Publikováno v:
Journal of Visualized Experiments
The mounting of microcrystals (
Autor:
Jeremy R. Keown, Adam D. Crawshaw, Jose Trincao, Loïc Carrique, Richard J. Gildea, Sam Horrell, Anna J. Warren, Danny Axford, Robin Owen, Gwyndaf Evans, Annie Bézier, Peter Metcalf, Jonathan M. Grimes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Infectious protein crystals are an essential part of the viral lifecycle for double-stranded DNA Baculoviridae and double-stranded RNA cypoviruses. These viral protein crystals, termed occlusion bodies or polyhedra, are dense protein assembl
Externí odkaz:
https://doaj.org/article/52663ececd974c08bbcf8a519f0e1636
Autor:
Kawal Sawhney, Anna J. Warren, Gwyndaf Evans, David Laundy, José Trincão, Graham Duller, V. P. Dhamgaye
Publikováno v:
AIP Conference Proceedings.
Third generation synchrotron radiation sources offer the possibility of using high demagnification ratio optics to achieve a micro-focused X-ray beam profile of size less than one micrometre size. This is highly advantageous for a variety of experime
Autor:
Teresa A. Figueiredo, Maria João Romão, Micael Silva, Teresa Santos-Silva, Rita G. Sobral, José Trincão, Eurico J. Cabrita, Hermínia de Lencastre, Ana Madalena Ludovice, Francisco Leisico, Diana Vieira
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The authors thank the Oxford Protein Production Facility, Research Complex (Harwell, Didcot, UK) for access to high-throughput facilities and assistance during the experiments; beamline staff at I02 and I04 for assistance during data collection at Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567b5df06b42b316436b605e1eb7b873
http://www.scopus.com/inward/record.url?scp=85044530342&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85044530342&partnerID=8YFLogxK
Autor:
Paul R. Raithby, Lauren E. Hatcher, Sara Fuertes, José Trincão, Michael Towrie, Ian P. Clarke, Charles C. Wilson, Jeppe Christensen, Mark R. Warren, Christopher H. Woodall, Michelle L. Hamilton, David R. Allan
Publikováno v:
Chemistry – A European Journal. 20:3128-3134
At temperatures below 150 K, the photoactivated metastable endo‐nitrito linkage isomer [Ni(Et4dien)(η2‐O,ON)(η1‐ONO)] (Et4dien=N,N,N′,N′‐tetraethyldiethylenetriamine) can be generated with 100 % conversion from the ground state nitro‐
Publikováno v:
Biochemical Society Transactions. 41:1260-1264
To understand the mechanism of biological processes, time-resolved methodologies are required to investigate how functionality is linked to changes in molecular structure. A number of spectroscopic techniques are available that probe local structural
Autor:
Catarina Coelho, Mineko Terao, Silke Leimkühler, Martin Mahro, Alexandra T. P. Carvalho, Maria João Romão, José Trincão, Maria J. Ramos, Enrico Garattini
Publikováno v:
Journal of Biological Chemistry. 287:40690-40702
Aldehyde oxidases (AOXs) are homodimeric proteins belonging to the xanthine oxidase family of molybdenum-containing enzymes. Each 150-kDa monomer contains a FAD redox cofactor, two spectroscopically distinct [2Fe-2S] clusters, and a molybdenum cofact
Autor:
Mineko Terao, Martin Mahro, José Trincão, Maria João Romão, Miguel Saggu, Friedhelm Lendzian, Silke Leimkühler, David Rodrigues, Catarina Coelho, Enrico Garattini, Peter Hildebrandt
Publikováno v:
Drug Metabolism and Disposition. 39:1939-1945
Aldehyde oxidase (AOX) is characterized by a broad substrate specificity, oxidizing aromatic azaheterocycles, such as N(1)-methylnicotinamide and N-methylphthalazinium, or aldehydes, such as benzaldehyde, retinal, and vanillin. In the past decade, AO