Zobrazeno 1 - 10
of 14
pro vyhledávání: '"José Sánchez-Collado"'
Publikováno v:
Cells, Vol 10, Iss 6, p 1308 (2021)
The interplay between the Ca2+-sensitive adenylyl cyclase 8 (AC8) and Orai1 channels plays an important role both in the activation of the cAMP/PKA signaling and the modulation of Orai1-dependent Ca2+ signals. AC8 interacts with a N-terminal region t
Externí odkaz:
https://doaj.org/article/49060e8b57fa4169b4cbfb27c4bab832
Autor:
Isaac Jardín, José J. López, Raquel Diez, José Sánchez-Collado, Carlos Cantonero, Letizia Albarrán, Geoffrey E. Woodard, Pedro C. Redondo, Ginés M. Salido, Tarik Smani, Juan A. Rosado
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
According to the International Association for the Study of Pain (IASP) pain is characterized as an “unpleasant sensory and emotional experience associated with actual or potential tissue damage”. The TRP super-family, compressing up to 28 isofor
Externí odkaz:
https://doaj.org/article/4d32a674e4e14723a9a41d5307330727
Autor:
Alejandro Berna-Erro, Jose Sanchez-Collado, Joel Nieto-Felipe, Alvaro Macias-Diaz, Pedro C. Redondo, Tarik Smani, Jose J. Lopez, Isaac Jardin, Juan A. Rosado
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1284 (2023)
The STIM family of proteins plays a crucial role in a plethora of cellular functions through the regulation of store-operated Ca2+ entry (SOCE) and, thus, intracellular calcium homeostasis. The two members of the mammalian STIM family, STIM1 and STIM
Externí odkaz:
https://doaj.org/article/d338353c87b3474ea2249b251936eedf
Autor:
Jose Sanchez-Collado, Jose J. Lopez, Carlos Cantonero, Isaac Jardin, Sergio Regodón, Pedro C. Redondo, Juan Gordillo, Tarik Smani, Gines M. Salido, Juan A. Rosado
Publikováno v:
Cancers, Vol 15, Iss 4, p 1290 (2023)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/749705edc92044db97bfe22198a5a67c
Autor:
Jose Sanchez-Collado, Joel Nieto-Felipe, Isaac Jardin, Rajesh Bhardwaj, Alejandro Berna-Erro, Gines M. Salido, Tarik Smani, Matthias A Hediger, Jose J. Lopez, Juan A. Rosado
Publikováno v:
Cancers, Vol 15, Iss 1, p 203 (2022)
N-linked glycosylation is a post-translational modification that affects protein function, structure, and interaction with other proteins. The store-operated Ca2+ entry (SOCE) core proteins, Orai1 and STIM1, exhibit N-glycosylation consensus motifs.
Externí odkaz:
https://doaj.org/article/f12cbab8bf1a4b5d8573f82a3e64835e
Autor:
Isaac Jardin, Alejandro Berna-Erro, Joel Nieto-Felipe, Alvaro Macias, Jose Sanchez-Collado, Jose J. Lopez, Gines M. Salido, Juan A. Rosado
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14568 (2022)
Orai1, the first identified member of the Orai protein family, is ubiquitously expressed in the animal kingdom. Orai1 was initially characterized as the channel responsible for the store-operated calcium entry (SOCE), a major mechanism that allows cy
Externí odkaz:
https://doaj.org/article/0531e30ecf4b449ab52b29d8f83e26e4
Autor:
Ericka Martínez-Martínez, Víctor Hugo Sánchez-Vázquez, Daniel León-Aparicio, Jose Sanchez-Collado, Martín-Leonardo Gallegos-Gómez, Juan A. Rosado, Juan M. Arias, Agustin Guerrero-Hernández
Publikováno v:
Cells, Vol 11, Iss 13, p 2037 (2022)
The overexpression of the Orai1 channel inhibits SOCE when using the Ca2+ readdition protocol. However, we found that HeLa cells overexpressing the Orai1 channel displayed enhanced Ca2+ entry and a limited ER depletion in response to the combination
Externí odkaz:
https://doaj.org/article/761cc246c8154200a156a3c6f0ea3bac
Autor:
Isaac Jardin, Jose J. Lopez, Jose Sanchez-Collado, Luis J. Gomez, Gines M. Salido, Juan A. Rosado
Publikováno v:
Cells, Vol 11, Iss 8, p 1332 (2022)
Tumors are composed by a heterogeneous population of cells. Among them, a sub-population of cells, termed cancer stem cells, exhibit stemness features, such as self-renewal capabilities, disposition to differentiate to a more proliferative state, and
Externí odkaz:
https://doaj.org/article/f2c9317313f44cafb31587a129282674
Autor:
Letizia Albarran, Jose J. Lopez, Isaac Jardin, Jose Sanchez-Collado, Alejandro Berna-Erro, Tarik Smani, Pedro J. Camello, Gines M. Salido, Juan A. Rosado
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 3, Pp 1164-1178 (2018)
Background/Aims: STIM1 and Orai1 are the key components of store-operated Ca2+ entry (SOCE). Among the proteins involved in the regulation of SOCE, SARAF prevents spontaneous activation of SOCE and modulates STIM1 function. Methods: Cytosolic Ca2+ mo
Externí odkaz:
https://doaj.org/article/c2edcae6cd0440558839ef9c7d643b67
Autor:
Jose Sanchez-Collado, Jose J. Lopez, Carlos Cantonero, Isaac Jardin, Sergio Regodón, Pedro C. Redondo, Juan Gordillo, Tarik Smani, Gines M. Salido, Juan A. Rosado
Publikováno v:
Cancers, Vol 14, Iss 1, p 114 (2021)
Breast cancer is a heterogeneous disease from the histological and molecular expression point of view, and this heterogeneity determines cancer aggressiveness. Store-operated Ca2+ entry (SOCE), a major mechanism for Ca2+ entry in non-excitable cells,
Externí odkaz:
https://doaj.org/article/85fa4035ff7e43b49f9d84694f1e81f5