Zobrazeno 1 - 10
of 200
pro vyhledávání: '"José Roberto Meyer-Fernandes"'
Autor:
Plinio Marcos Freire dos Santos, Chyntia Carolina Díaz Acosta, Thabatta Leal Silveira Andrezo Rosa, Michelle Harumi Ishiba, André Alves Dias, Antonio Marcos Rodrigues Pereira, Luísa Domingos Gutierres, Melissa Pontes Pereira, Matheus da Silva Rocha, Patrícia Sammarco Rosa, Daniele F. F. Bertoluci, José Roberto Meyer-Fernandes, Fabricio da Mota Ramalho Costa, Maria Angela M. Marques, John T. Belisle, Roberta Olmo Pinheiro, Luciana Silva Rodrigues, Maria Cristina Vidal Pessolani, Marcia Berrêdo-Pinho
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundLeprosy is a chronic infectious disease caused by Mycobacterium leprae, which can lead to a disabling neurodegenerative condition. M. leprae preferentially infects skin macrophages and Schwann cells–glial cells of the peripheral nervous s
Externí odkaz:
https://doaj.org/article/f7ff13b38ef44228826448b683d0162b
Autor:
Samara Santos-Araujo, Fabio Gomes, Luiz Fernando Carvalho-Kelly, José Roberto Meyer-Fernandes, Katia C. Gondim, Isabela Ramos
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Autophagy is a cellular degradation pathway mediated by highly conserved autophagy-related genes (Atgs). In our previous work, we showed that inhibiting autophagy under starvation conditions leads to significant physiological changes in the insect ve
Externí odkaz:
https://doaj.org/article/1c5994f29acf429d9e99093b844a53a6
Publikováno v:
Membranes, Vol 13, Iss 1, p 42 (2022)
In addition to their standard inorganic phosphate (Pi) nutritional function, Pi transporters have additional roles in several cells, including Pi sensing (the so-called transceptor) and a crucial role in Pi metabolism, where they control several phen
Externí odkaz:
https://doaj.org/article/c6ab17aea0524514ad27a9c456a78019
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Belonging to the GDA1/CD39 protein superfamily, nucleoside triphosphate diphosphohydrolases (NTPDases) catalyze the hydrolysis of ATP and ADP to the monophosphate form (AMP) and inorganic phosphate (Pi). Several NTPDase isoforms have been described i
Externí odkaz:
https://doaj.org/article/f1a9010f933743be9cd394b44cf3cddd
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Protozoans of the genus Leishmania are the causative agents of an important neglected tropical disease referred to as leishmaniasis. During their lifecycle, the parasites can colonize the alimentary tract of the sand fly vector and the parasitophorou
Externí odkaz:
https://doaj.org/article/1d0a985e3ada49c5b166e10f7a704204
Autor:
Mariana Afonso, Ana Rita Mestre, Guilherme Silva, Ana Catarina Almeida, Rodrigo A. Cunha, José Roberto Meyer-Fernandes, Teresa Gonçalves, Lisa Rodrigues
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Host innate immunity is fundamental to the resistance against Candida albicans and Candida glabrata infection, two of the most important agents contributing to human fungal infections. Phagocytic cells, such as neutrophils, constitute the first line
Externí odkaz:
https://doaj.org/article/5dcf4b7b8a39484d83925c7bb2aad105
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
In the Leishmania lifecycle, the motile promastigote form is transmitted from the sand fly vector to a mammalian host during a blood meal. Inside vertebrate host macrophages, the parasites can differentiate into the amastigote form and multiply, caus
Externí odkaz:
https://doaj.org/article/f9d61fc3b48e4c158b63d861e0d3e15a
Autor:
Paula Alvarenga Borges, Ingrid Waclawiak, Janaína Lima Georgii, Vanderlei da Silva Fraga-Junior, Janaína Figueiredo Barros, Felipe Simões Lemos, Thaís Russo-Abrahão, Elvira Maria Saraiva, Christina M. Takiya, Robson Coutinho-Silva, Carmen Penido, Claudia Mermelstein, José Roberto Meyer-Fernandes, Fábio B. Canto, Josiane Sabbadini Neves, Paulo A. Melo, Claudio Canetti, Claudia Farias Benjamim
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chronic wounds are a public health problem worldwide, especially those related to diabetes. Besides being an enormous burden to patients, it challenges wound care professionals and causes a great financial cost to health system. Considering the absen
Externí odkaz:
https://doaj.org/article/05ea3e3283e24c8abf88a07d23bfa717
Publikováno v:
Cells, Vol 9, Iss 10, p 2225 (2020)
The ENA ATPases (from exitus natru: the exit of sodium) belonging to the P-type ATPases are structurally very similar to the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA); they exchange Na+ for H+ and, therefore, are also known as Na+-ATPases. ENA
Externí odkaz:
https://doaj.org/article/12494292fe1a4f158290efba9798ce96
Autor:
Thais Russo-Abrahão, Marco Antônio Lacerda-Abreu, Tainá Gomes, Daniela Cosentino-Gomes, Ayra Diandra Carvalho-de-Araújo, Mariana Figueiredo Rodrigues, Ana Carolina Leal de Oliveira, Franklin David Rumjanek, Robson de Queiroz Monteiro, José Roberto Meyer-Fernandes
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191270 (2018)
Recent studies demonstrate that interstitial inorganic phosphate is significantly elevated in the breast cancer microenvironment as compared to normal tissue. In addition it has been shown that breast cancer cells express high levels of the NaPi-IIb
Externí odkaz:
https://doaj.org/article/d5d780c6f9a54ee5800f5444272f2198