Zobrazeno 1 - 10
of 140
pro vyhledávání: '"José R. Penadés"'
Autor:
Lingchen He, Laura Miguel-Romero, Jonasz B. Patkowski, Nasser Alqurainy, Eduardo P. C. Rocha, Tiago R. D. Costa, Alfred Fillol-Salom, José R. Penadés
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Many bacterial immune systems recognize phage structural components to activate antiviral responses, without inhibiting the function of the phage component. These systems can be encoded in specific chromosomal loci, known as defense islands,
Externí odkaz:
https://doaj.org/article/b98ef47ae13041da90e6cd058eed4d51
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Bacteriophages (phages) are the most abundant biological entities on Earth, exerting a significant influence on the dissemination of bacterial virulence, pathogenicity, and antimicrobial resistance. Temperate phages integrate into the bacter
Externí odkaz:
https://doaj.org/article/5d7ebedb67804fe5ac524a0911845bdb
Autor:
Sergio Arredondo-Alonso, George Blundell-Hunter, Zuyi Fu, Rebecca A. Gladstone, Alfred Fillol-Salom, Jessica Loraine, Elaine Cloutman-Green, Pål J. Johnsen, Ørjan Samuelsen, Anna K. Pöntinen, François Cléon, Susana Chavez-Bueno, Miguel A. De la Cruz, Miguel A. Ares, Manivanh Vongsouvath, Agnieszka Chmielarczyk, Carolyne Horner, Nigel Klein, Alan McNally, Joice N. Reis, José R. Penadés, Nicholas R. Thomson, Jukka Corander, Peter W. Taylor, Alex J. McCarthy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Escherichia coli is a leading cause of invasive bacterial infections in humans. Capsule polysaccharide has an important role in bacterial pathogenesis, and the K1 capsule has been firmly established as one of the most potent capsule types in
Externí odkaz:
https://doaj.org/article/e6fa52774e4f424f982560f7102a17a7
Publikováno v:
Advanced Science, Vol 10, Iss 24, Pp n/a-n/a (2023)
Abstract Phage‐inducible chromosomal islands (PICIs) are a family of phage satellites that hijack phage components to facilitate their mobility and spread. Recently, these genetic constructs are repurposed as antibacterial drones, enabling a new to
Externí odkaz:
https://doaj.org/article/3efc2380140d48e8b9e769ac00405bf1
Autor:
Francisca Gallego del Sol, Nuria Quiles-Puchalt, Aisling Brady, José R. Penadés, Alberto Marina
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The arbitrium system is a peptide-based communication system to coordinate the lysis-lysogenic cycle of phages infecting bacteria. Here Gallego del Sol et al. provide the crystal structure of Aim-receptor of Katmira phage infecting B. subtilis in apo
Externí odkaz:
https://doaj.org/article/9aebc82476f64d2384281500718eb6b6
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Stl, the master repressor of the Staphylococcus aureus pathogenicity islands (SaPIs), targets phage-encoded proteins to derepress and synchronize the SaPI and the helper phage life cycles. To activate their cycle, some SaPI Stls target both
Externí odkaz:
https://doaj.org/article/60c9cda5c2a44f358c3cb9422d2d1a47
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Phage-inducible chromosomal islands (PICIs) are a group of mobile genetic elements that hijack the replication and assembly machinery of helper bacteriophages. Here the authors describe a mechanism by which a group of PICIs from Staphylococcus aureus
Externí odkaz:
https://doaj.org/article/da55d0792fca4a61898243c4aebc8006
Autor:
Suzanne Humphrey, Alfred Fillol-Salom, Nuria Quiles-Puchalt, Rodrigo Ibarra-Chávez, Andreas F. Haag, John Chen, José R. Penadés
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
It is commonly thought that horizontal transfer of most bacterial chromosomal genes is limited, in comparison with the frequent transfer of mobile genetic elements. Humphrey et al. show that, actually, phage-mediated lateral transduction of core chro
Externí odkaz:
https://doaj.org/article/ff9c8f8cf68d45bebb954b3a88c38374
Autor:
Alfred Fillol-Salom, Rodrigo Bacigalupe, Suzanne Humphrey, Yin Ning Chiang, John Chen, José R. Penadés
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
During the transition from lysogeny (a stable association between a phage and its bacterial host) to the lytic cycle, prophage excision can be followed or preceded by DNA replication and packaging. Here, the authors show that prophage excision is del
Externí odkaz:
https://doaj.org/article/6959862482bf4a9bbc899bd86e3da205
Autor:
Suzanne Humphrey, Álvaro San Millán, Macarena Toll-Riera, John Connolly, Alejandra Flor-Duro, John Chen, Carles Ubeda, R. Craig MacLean, José R. Penadés
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Many plasmids can be transferred between bacterial cells via conjugation; however, the mechanisms underlying the transfer of non-conjugative plasmids are less clear. Here, Humphrey et al. show that staphylococcal phages and a family of pathogenicity
Externí odkaz:
https://doaj.org/article/223838baccfd4b7e90e35bc7462be767