Zobrazeno 1 - 3
of 3
pro vyhledávání: '"José R. González-Escalada"'
Publikováno v:
Neuropharmacology. 42:210-220
Topiramate (TPM) is an antiepileptic with several proposed mechanisms of action including the inhibition of carbonic anhydrase (CA). Since the activity of this enzyme is essential for the generation of GABA(A)-mediated depolarizing responses, which a
Publikováno v:
Brain research bulletin. 83(6)
Levodopa has been shown to produce analgesia in various clinical and experimental settings, but its use for chronic pain treatment has not been established. We have undertaken a study of the antiallodynic actions of levodopa in a rat model of painful
Autor:
José M. Solís, Manuel Ruiz, Nuria Del Olmo, Luz M. Suárez, Francisco Suárez, José R. González-Escalada
Publikováno v:
The European journal of neuroscience. 21(1)
Gabapentin is a drug with anticonvulsant and analgesic properties causing the reduction of neurotransmitter release. We show that one of the mechanisms implicated in this effect of gabapentin is the reduction of the axon excitability measured as an a