Zobrazeno 1 - 10 of 13 pro vyhledávání: '"José Pedrazzoli Júnior"'
1
Akademický článek
Determination of nimodipine in plasma by HPLC-MS/MS and pharmacokinetic application
Autor: Demétrius Fernandes do Nascimento, Manoel Odorico de Moraes, Fernando Antônio Frota Bezerra, Andréa Vieira Pontes, Célia Regina Amaral Uchoa, Renata Amaral de Moraes, Ismenia Osório Leite, Gilmara Silva de Melo Santana, Ana Paula Macedo Santana, Ana Lourdes Almeida e Silva Leite, José Pedrazzoli Júnior, Maria Elisabete Amaral de Moraes
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 46, Iss 4, Pp 665-677 (2010)
To develop and validate a rapid, specific and highly sensitive method to quantify nimodipine in human plasma using dibucaine as the internal standard (IS). The analyte and IS were extracted from plasma samples by liquid-liquid extraction using hexane
Externí odkaz: https://doaj.org/article/3c20306264dd4c59852359314af9e599
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2
Biodisponibilidade Relativa/Bioequivalência entre duas formulações orais de rivaroxabana (20mg) em participantes brasileiros saudáveis, em condições de jejum e alimentação: Relative Bioavailability/Bioequivalence between two oral formulations of rivaroxaban (20 mg) in healthy Brazilian subjects, under fasting and fed conditions
Autor: Juliana Loschi, Luciana Montes Rezende, Rodolfo Rodrigo Pereira Santos, Silvana Aparecida Calafatti Carandina, José Jorge Gabbai, Giulia Minuti, Abrão Abuhab, José Pedrazzoli Júnior
Publikováno v: Brazilian Journal of Health Review; Vol. 5 No. 5 (2022); 17332-17346
Brazilian Journal of Health Review; v. 5 n. 5 (2022); 17332-17346
Brazilian Journal of Health Review
Federação das Indústrias do Estado do Paraná (FIEP)
instacron:BJRH
O estudo teve como objetivo avaliar a bioequivalência entre dois comprimidos revestidos de rivaroxabana em participantes brasileiros saudáveis após administração em dose única em condições de jejum e alimentação. Dois estudos foram conduzid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0bed42fa0b2051a83b2fb753838a0f
https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/51716
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3
Preclinical Evaluation of Ropivacaine in 2 Liposomal Modified Systems
Autor: Cíntia Maria Saia Cereda, Eneida de Paula, Carolina C. Rennó, José Pedrazzoli Júnior, Juliana Zampoli Boava Papini, Elizabeth Ferreira Martinez, Giovana Radomille Tofoli, Victor Angelo Martins Montalli, Silvana Aparecida Calafatti
Publikováno v: Obstetric Anesthesia Digest. 40:48-49
BACKGROUND Our research group has recently developed liposomes with ionic gradient and in a combined manner as donor and acceptor vesicles containing ropivacaine (RVC; at 2% or 0.75%). Looking for applications of such novel formulations for postopera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a6e6fccb9c5eff3ffc030953c85501
https://doi.org/10.1097/01.aoa.0000652968.54529.71
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5
Pharmacokinetics and Pharmacodynamics Evaluation of Tramadol in Thermoreversible Gels
Autor: Juliana Zampoli Boava Papini, Cíntia Maria Saia Cereda, José Pedrazzoli Júnior, Daniele Ribeiro de Araujo, Silvana Aparecida Calafatti, Giovana Radomille Tofoli
Publikováno v: BioMed Research International, Vol 2017 (2017)
BioMed Research International
We evaluated pharmacokinetics (PK) and pharmacodynamics (PD) induced by new formulations of tramadol (TR) in thermoreversible gels. The poloxamer- (PL-) tramadol systems were prepared by direct dispersion of the drug in solutions with PL 407 and PL 1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df54b35004c7b5df95011e49225a258
https://doaj.org/article/88cb53c3628f45a88b3f458beb461c2a
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6
Pharmacokinetic study of liposome-encapsulated and plain mepivacaine formulations injected intra-orally in volunteers
Autor: Francisco Carlos Groppo, Silvana Aparecida Calafatti, Eneida de Paula, F.A.P. Barros, José Pedrazzoli Júnior, Daniele Ribeiro de Araujo, Giovana Radomille Tofoli, Daiane Quaglio, Cíntia Maria Saia Cereda, Michelle Franz-Montan
Publikováno v: Journal of Pharmacy and Pharmacology. 64:397-403
Objectives The pharmacokinetics of commercial and liposome-encapsulated mepivacaine (MVC) injected intra-orally in healthy volunteers was studied. Methods In this double blind, randomized cross-over study, 15 volunteers received, at four different se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83501ee71b88930b1f5327adc1d6d6e5
https://doi.org/10.1111/j.2042-7158.2011.01425.x
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7
Determination of nimodipine in plasma by HPLC-MS/MS and pharmacokinetic application
Autor: Manoel Odorico de Moraes, Gilmara Silva de Melo Santana, Demétrius Fernandes do Nascimento, José Pedrazzoli Júnior, Ana Paula M. Santana, Célia Regina Amaral Uchoa, Fernando Antônio Frota Bezerra, Andréa Vieira Pontes, Maria Elisabete Amaral de Moraes, Ana Lourdes Almeida e Silva Leite, Ismenia Osório Leite, Renata Amaral de Moraes
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Volume: 46, Issue: 4, Pages: 665-677, Published: DEC 2010
Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC
Brazilian Journal of Pharmaceutical Sciences; Vol. 46 No. 4 (2010); 665-677
Brazilian Journal of Pharmaceutical Sciences; Vol. 46 Núm. 4 (2010); 665-677
Brazilian Journal of Pharmaceutical Sciences; v. 46 n. 4 (2010); 665-677
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 46, Iss 4, Pp 665-677 (2010)
To develop and validate a rapid, specific and highly sensitive method to quantify nimodipine in human plasma using dibucaine as the internal standard (IS). The analyte and IS were extracted from plasma samples by liquid-liquid extraction using hexane
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b15aef18917aff8b738444a7659e526
https://doi.org/10.1590/s1984-82502010000400008
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9
Expression of Toll-like receptors in enterocromaffin-like cells and their function in histamine release
Autor: Rafael Martins de Oliveira, Lúcio Fábio Caldas Ferraz, José Pedrazzoli Júnior, Marcelo Lima Ribeiro, Carolina Bernardi Stefani, Angélica Aparecida Antoniellis Silveira, Alessandra Gambero
Publikováno v: Digestive diseases and sciences. 57(9)
Enterocromaffin-like cells (ECL) are specialized endocrine gastric cells able to release histamine, which in turn controls gastric acid production by parietal cells. Helicobacter pylori infection and other conditions signal in the gastrointestinal tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3debd60d2c9edbb32f6559fb302dbb8d
https://pubmed.ncbi.nlm.nih.gov/22618577
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10
Pharmacokinetic and local toxicity studies of liposome-encapsulated and plain mepivacaine solutions in rats
Autor: F.A.P. Barros, Maria Cristina Volpato, Rui Barbosa de Brito Junior, Cíntia Maria Saia Cereda, Giovana Radomille Tofoli, Daniele Ribeiro de Araujo, Francisco Carlos Groppo, José Ranali, José Pedrazzoli Júnior, Eduardo C. Meurer, Eneida de Paula
Publikováno v: Drug delivery. 17(2)
The pharmacokinetics and the local toxicity of commercial and liposome-encapsulated mepivacaine formulations injected intra-orally in rats were studied. Animals were divided in groups (n = 4-6) and treated with 0.1 mL of the formulations: 2% mepivaca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ac09a6b4a2481c02c16451eed82d8d
https://pubmed.ncbi.nlm.nih.gov/20070242
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