Zobrazeno 1 - 10
of 35
pro vyhledávání: '"José P. Guirao-Abad"'
Autor:
Alejandra Argüelles, Ruth Sánchez-Fresneda, José P. Guirao-Abad, José Antonio Lozano, Francisco Solano, Juan-Carlos Argüelles
Publikováno v:
Journal of Fungi, Vol 9, Iss 4, p 442 (2023)
Fungi have traditionally been considered opportunistic pathogens in primary infections caused by virulent bacteria, protozoan, or viruses. Consequently, antimycotic chemotherapy is clearly less developed in comparison to its bacterial counterpart. Cu
Externí odkaz:
https://doaj.org/article/6ef494f0602e45a3a28e7ba667bec523
Publikováno v:
Current Research in Microbial Sciences, Vol 3, Iss , Pp 100119- (2022)
One of the most potent opportunistic fungal pathogens of humans is Aspergillus fumigatus, an environmental mold that causes a life-threatening pneumonia with a high rate of morbidity and mortality. Despite advances in therapy, issues of drug toxicity
Externí odkaz:
https://doaj.org/article/153fec2477c84a678df67f2e83f970ca
Autor:
José P. Guirao-Abad, Martin Weichert, Ginés Luengo-Gil, Sarah Sze Wah Wong, Vishukumar Aimanianda, Christina Grisham, Nikita Malev, Shivani Reddy, Laura Woollett, David S. Askew
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
The fungal UPR is an adaptive signaling pathway in the ER that buffers fluctuations in ER stress but also serves as a virulence regulatory hub in species of pathogenic fungi that rely on secretory pathway homeostasis for pathogenicity. This study dem
Externí odkaz:
https://doaj.org/article/fa945191fa4942a0a1c0c0808abce8b6
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT The unfolded protein response (UPR) is a signaling network that maintains homeostasis of the endoplasmic reticulum (ER). In the human-pathogenic fungus Aspergillus fumigatus, the UPR is initiated by activation of an endoribonuclease (RNase)
Externí odkaz:
https://doaj.org/article/de64c7c49fec4315af7cd50de0ba93da
Autor:
Rebeca Alonso-Monge, José P. Guirao-Abad, Ruth Sánchez-Fresneda, Jesús Pla, Genoveva Yagüe, Juan Carlos Argüelles
Publikováno v:
Microorganisms, Vol 8, Iss 12, p 1867 (2020)
In fungi, the Mitogen-Activated Protein kinase (MAPK) pathways sense a wide variety of environmental stimuli, leading to cell adaptation and survival. The HOG pathway plays an essential role in the pathobiology of Candida albicans, including the colo
Externí odkaz:
https://doaj.org/article/305602fc7a5a444086d25fd1a14d0075
Autor:
Alejandra Argüelles, Ruth Sánchez-Fresneda, José P. Guirao-Abad, Cristóbal Belda, José Antonio Lozano, Francisco Solano, Juan-Carlos Argüelles
Publikováno v:
Microorganisms, Vol 8, Iss 5, p 749 (2020)
The potential fungicidal action of the natural extracts, carnosic acid (obtained from rosemary) and propolis (from honeybees’ panels) against the highly prevalent yeast Candida albicans, used herein as an archetype of pathogenic fungi, was tested.
Externí odkaz:
https://doaj.org/article/71c6da43ae354b099fa50a3b2d3cce24
Autor:
Ana Morales-Menchén, Federico Navarro-García, José P. Guirao-Abad, Elvira Román, Daniel Prieto, Ioana V. Coman, Jesús Pla, Rebeca Alonso-Monge
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Certain yeasts secrete peptides known as killer toxins or mycocins with a deleterious effect on sensitive yeasts or filamentous fungi, a common phenomenon in environmental species. In a recent work, different Debaryomyces hansenii (Dh) strains isolat
Externí odkaz:
https://doaj.org/article/b6e5338716de47eb88e7e03a4c8fc15b
Autor:
Ruth Sánchez-Fresneda, Vanessa Pujante, Juan-Carlos Argüelles, José P. Guirao-Abad, Genoveva Yagüe
Publikováno v:
Journal of Medical Microbiology. 68:1479-1488
Purpose. Fungal infections have increased in recent decades, with Candida albicans being the fourth most common aetiological agent of nosocomial infections. Disaccharide trehalose has been proposed as a target for the development of new antifungals.
Publikováno v:
Current research in microbial sciences. 3
One of the most potent opportunistic fungal pathogens of humans is
Autor:
Ginés Luengo-Gil, Shivani Reddy, David S. Askew, Laura A. Woollett, Vishukumar Aimanianda, Sarah Sze Wah Wong, José P. Guirao-Abad, Nikita Malev, Christina Grisham, Martin Weichert
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
mBio
mBio, 2021, 12 (5), pp.e0273521. ⟨10.1128/mBio.02735-21⟩
mBio
mBio, 2021, 12 (5), pp.e0273521. ⟨10.1128/mBio.02735-21⟩
International audience; Aspergillus fumigatus is a human-pathogenic mold that extracts nutrients from the environment or from host tissues by secreting hydrolytic enzymes. The ability of A. fumigatus to adjust secretion levels in proportion to demand